Free for academic non-profit institutions. Other users need a Commercial license

Aliases for NPIPB11 Gene

Aliases for NPIPB11 Gene

  • Nuclear Pore Complex Interacting Protein Family Member B11 2 3 5
  • Nuclear Pore Complex-Interacting Protein Family Member B11 3 4
  • Nuclear Pore Complex Interacting Protein Family, Member B11 2
  • Hepatitis B Virus Pre-Pre-S Promoter DNA-Binding Protein 3
  • NPIP-Like Locus 3
  • Pps22-1 Protein 3
  • NPIP 3

External Ids for NPIPB11 Gene

Summaries for NPIPB11 Gene

GeneCards Summary for NPIPB11 Gene

NPIPB11 (Nuclear Pore Complex Interacting Protein Family Member B11) is a Protein Coding gene. An important paralog of this gene is NPIPB4.

Additional gene information for NPIPB11 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NPIPB11 Gene

Genomics for NPIPB11 Gene

GeneHancer (GH) Regulatory Elements for NPIPB11 Gene

Promoters and enhancers for NPIPB11 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J029405 Enhancer 0.7 Ensembl ENCODE 600.7 -0.2 -223 2.6 NFIB SP7 NFIC ZKSCAN1 ZNF18 NPIPB11 GC16P029422
GH16J030063 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 23.1 -661.3 -661270 7.6 HDGF MTA3 SP1 ZNF652 CTCF ELF3 ZFX CBFA2T2 ZNF148 NKRF PIR61223 ALDOA SRCAP NPIPB12 SETD1A YPEL3 NPIPB13 RNF40 SMG1P5 NPIPB11
GH16J030367 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 13.6 -970.2 -970198 17.4 HDGF SP1 CC2D1A ELF3 ZFX MNT ZNF148 NKRF POLR2A MLLT1 MYLPF TBC1D10B SETD1A SRCAP NPIPB12 INO80E SMG1P5 ZNF764 FBRS ZNF747
GH16J028490 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 13.6 +911.7 911743 7.1 SP1 ZNF652 ZFX ELF3 ZKSCAN8 MNT SIX5 CBFA2T2 NKRF CEBPG APOBR ENSG00000261832 CLN3 SULT1A2 ATXN2L ENSG00000261766 SH2B1 ENSG00000260853 SPNS1 NFATC2IP
GH16J029862 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 13.6 -457.2 -457223 2.6 HDGF ZNF652 SP1 ZFX CC2D1A ELF3 CTCF SIX5 ZNF148 NKRF CDIPTOSP CDIPT ENSG00000278713 SRCAP SPNS1 ENSG00000260853 INO80E NFATC2IP PRR14 RNF40
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around NPIPB11 on UCSC Golden Path with GeneCards custom track

Genomic Locations for NPIPB11 Gene

Genomic Locations for NPIPB11 Gene
chr16:29,381,183-29,405,678
(GRCh38/hg38)
Size:
24,496 bases
Orientation:
Minus strand
chr16:29,392,675-29,415,759
(GRCh37/hg19)
Size:
23,085 bases
Orientation:
Minus strand

Genomic View for NPIPB11 Gene

Genes around NPIPB11 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NPIPB11 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NPIPB11 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NPIPB11 Gene

Proteins for NPIPB11 Gene

  • Protein details for NPIPB11 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    E5RHQ5-NPB11_HUMAN
    Recommended name:
    Nuclear pore complex-interacting protein family member B11
    Protein Accession:
    E5RHQ5

    Protein attributes for NPIPB11 Gene

    Size:
    1161 amino acids
    Molecular mass:
    129208 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NPIPB11 Gene

Post-translational modifications for NPIPB11 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for NPIPB11 Gene

No data available for DME Specific Peptides for NPIPB11 Gene

Domains & Families for NPIPB11 Gene

Gene Families for NPIPB11 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for NPIPB11 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

E5RHQ5

UniProtKB/Swiss-Prot:

NPB11_HUMAN :
  • Belongs to the NPIP family.
Family:
  • Belongs to the NPIP family.
genes like me logo Genes that share domains with NPIPB11: view

No data available for Suggested Antigen Peptide Sequences for NPIPB11 Gene

Function for NPIPB11 Gene

Phenotypes From GWAS Catalog for NPIPB11 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NPIPB11 Gene

Localization for NPIPB11 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NPIPB11 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for NPIPB11 gene
Compartment Confidence
nucleus 4

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for NPIPB11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005654 nucleoplasm IDA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with NPIPB11: view

Pathways & Interactions for NPIPB11 Gene

PathCards logo

SuperPathways for NPIPB11 Gene

No Data Available

Interacting Proteins for NPIPB11 Gene

Gene Ontology (GO) - Biological Process for NPIPB11 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for NPIPB11 Gene

Drugs & Compounds for NPIPB11 Gene

No Compound Related Data Available

Transcripts for NPIPB11 Gene

mRNA/cDNA for NPIPB11 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for NPIPB11 Gene

No ASD Table

Relevant External Links for NPIPB11 Gene

GeneLoc Exon Structure for
NPIPB11
ECgene alternative splicing isoforms for
NPIPB11

Expression for NPIPB11 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for NPIPB11 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for NPIPB11 Gene



NURSA nuclear receptor signaling pathways regulating expression of NPIPB11 Gene:

NPIPB11
genes like me logo Genes that share expression patterns with NPIPB11: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NPIPB11 Gene

Orthologs for NPIPB11 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for NPIPB11 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC750787 34
  • 91.38 (n)
-- 35
  • 74 (a)
ManyToMany
-- 35
  • 73 (a)
ManyToMany
Species where no ortholog for NPIPB11 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NPIPB11 Gene

ENSEMBL:
Gene Tree for NPIPB11 (if available)
TreeFam:
Gene Tree for NPIPB11 (if available)

Paralogs for NPIPB11 Gene

(21) SIMAP similar genes for NPIPB11 Gene using alignment to 1 proteins:

  • NPB11_HUMAN

Pseudogenes.org Pseudogenes for NPIPB11 Gene

genes like me logo Genes that share paralogs with NPIPB11: view

Variants for NPIPB11 Gene

Sequence variations from dbSNP and Humsavar for NPIPB11 Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1000106608 -- 29,401,726(-) G/C genic_upstream_transcript_variant, intron_variant
rs1000389092 -- 29,397,162(-) CTCT/CT intron_variant
rs1000672527 -- 29,383,214(-) G/A coding_sequence_variant, genic_downstream_transcript_variant, missense_variant
rs1000844812 -- 29,392,544(-) T/G intron_variant
rs1000875660 -- 29,392,350(-) G/A intron_variant

Variation tolerance for NPIPB11 Gene

Gene Damage Index Score: 3.08; 50.81% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for NPIPB11 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
NPIPB11

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for NPIPB11 Gene

Disorders for NPIPB11 Gene

Additional Disease Information for NPIPB11

No disorders were found for NPIPB11 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NPIPB11 Gene

Publications for NPIPB11 Gene

  1. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J … Pennacchio LA (Nature 2004) 3 4 58

Products for NPIPB11 Gene

Sources for NPIPB11 Gene

Content
Loading form....