Aliases for NPBWR2 Gene
External Ids for NPBWR2 Gene
Previous HGNC Symbols for NPBWR2 Gene
Previous GeneCards Identifiers for NPBWR2 Gene
The protein encoded by this gene is an integral membrane protein and G protein-coupled receptor. The encoded protein is similar in sequence to another G protein-coupled receptor (GPR7), and it is structurally similar to opioid and somatostatin receptors. This protein binds neuropeptides B and W. This gene is intronless and is expressed primarily in the frontal cortex of the brain. [provided by RefSeq, Jul 2008]
GeneCards Summary for NPBWR2 Gene
NPBWR2 (Neuropeptides B And W Receptor 2) is a Protein Coding gene. Diseases associated with NPBWR2 include Autosomal Recessive Non-Syndromic Intellectual Disability. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and neuropeptide receptor activity. An important paralog of this gene is NPBWR1.
UniProtKB/Swiss-Prot Summary for NPBWR2 Gene
Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals.