Aliases for NOVA1 Gene
External Ids for NOVA1 Gene
Previous GeneCards Identifiers for NOVA1 Gene
This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
GeneCards Summary for NOVA1 Gene
NOVA1 (NOVA Alternative Splicing Regulator 1) is a Protein Coding gene. Diseases associated with NOVA1 include Partial Fetal Alcohol Syndrome and Low-Grade Astrocytoma. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and RNA binding. An important paralog of this gene is NOVA2.
UniProtKB/Swiss-Prot Summary for NOVA1 Gene
May regulate RNA splicing or metabolism in a specific subset of developing neurons.