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The protein encoded by this gene may modulate the activity and localization of nitric oxide synthase (endothelial and neuronal) and thus nitric oxide production. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2012] See more...
Aliases for NOSIP Gene
Aliases for NOSIP Gene
External Ids for NOSIP Gene
- HGNC: 17946
- Entrez Gene: 51070
- Ensembl: ENSG00000142546
- OMIM: 616759
- UniProtKB: Q9Y314
Previous GeneCards Identifiers for NOSIP Gene
- GC19M050717
- GC19M050427
- GC19M054734
- GC19M054751
- GC19M054752
- GC19M054753
- GC19M050058
- GC19M046436
Summaries for NOSIP Gene
-
The protein encoded by this gene may modulate the activity and localization of nitric oxide synthase (endothelial and neuronal) and thus nitric oxide production. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2012]
GeneCards Summary for NOSIP Gene
NOSIP (Nitric Oxide Synthase Interacting Protein) is a Protein Coding gene. Diseases associated with NOSIP include Polyomavirus-Associated Nephropathy. Among its related pathways are eNOS activation and regulation and Nanog in Mammalian ESC Pluripotency.
UniProtKB/Swiss-Prot Summary for NOSIP Gene
-
E3 ubiquitin-protein ligase that is essential for proper development of the forebrain, the eye, and the face. Catalyzes monoubiquitination of serine/threonine-protein phosphatase 2A (PP2A) catalytic subunit PPP2CA/PPP2CB (By similarity). Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity (PubMed:11149895, PubMed:15548660, PubMed:16135813).
Additional gene information for NOSIP Gene
- HGNC(17946)
- Entrez Gene(51070)
- Ensembl(ENSG00000142546)
- OMIM(616759)
- UniProtKB(Q9Y314)
- Open Targets Platform(ENSG00000142546)
- Search for NOSIP at DataMed
- Search for NOSIP at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for NOSIP Gene
Genomics for NOSIP Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for NOSIP Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around NOSIP on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for NOSIP
- Top Transcription factor binding sites by QIAGEN in the NOSIP gene promoter:
-
- c-Myb
- Egr-2
- Egr-4
- HOXA5
- NF-kappaB
- NF-kappaB1
- p53
- RelA
- STAT5A
- Zic3
Genomic Locations for NOSIP Gene
Genomic Locations for NOSIP Gene
- chr19:49,555,468-49,590,262
- (GRCh38/hg38)
- Size:
- 34,795 bases
- Orientation:
- Minus strand
- chr19:50,058,968-50,093,519
- (GRCh37/hg19)
- Size:
- 34,552 bases
- Orientation:
- Minus strand
Genomic View for NOSIP Gene
Genes around NOSIP on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.33 by HGNC
- 19q13.33 by Entrez Gene
- 19q13.33 by Ensembl
NOSIP Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for NOSIP Gene
Proteins for NOSIP Gene
-
Protein details for NOSIP Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9Y314-NOSIP_HUMAN
- Recommended name:
- Nitric oxide synthase-interacting protein
- Protein Accession:
- Q9Y314
- Q96FD2
Protein attributes for NOSIP Gene
- Size:
- 301 amino acids
- Molecular mass:
- 33172 Da
- Quaternary structure:
-
- Interacts with NOS1 and NOS3 (PubMed:11149895, PubMed:15548660). Interacts with PP2A holoenzyme, containing PPP2CA, PPP2CB, PPP2R1A and PPP2R2A subunits (By similarity).
Protein Expression for NOSIP Gene
Post-translational modifications for NOSIP Gene
Other Protein References for NOSIP Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- LifeSpan BioSciences NOSIP Antibody
- Novus Biologicals Antibodies for NOSIP
-
Abcam antibodies for NOSIP
- Invitrogen Antibodies for NOSIP (AFLGC-NOSIP)
-
Santa Cruz Biotechnology (SCBT) Antibodies for NOSIP
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for NOSIP
- Origene Custom Protein Services for NOSIP
- antibodies-online: Show 10 available NOSIP Proteins ranked by validation data
- Compare Top NOSIP Proteins
-
Quality Products:
-
Signalway Proteins for NOSIP
-
Abcam proteins for NOSIP
Assay Products
- antibodies-online: Show 10 available NOSIP Elisa Kits ranked by validation data
- Compare Top NOSIP Elisa Kits
-
Quality Products:
-
Signalway ELISA kits for NOSIP
No data available for DME Specific Peptides for NOSIP Gene
Domains & Families for NOSIP Gene
Gene Families for NOSIP Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted intracellular proteins
Protein Domains for NOSIP Gene
- InterPro:
- Blocks:
-
- Zn-finger, modified RING
- ProtoNet:
Suggested Antigen Peptide Sequences for NOSIP Gene
- GenScript: Design optimal peptide antigens:
-
- eNOS-interacting protein (NOSIP_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9Y314UniProtKB/Swiss-Prot:
NOSIP_HUMAN :- The U-box-like region is a truncated U-box domain. It is unknown whether it is functional or not.
- Belongs to the NOSIP family.
- Domain:
-
- The U-box-like region is a truncated U-box domain. It is unknown whether it is functional or not.
- Family:
-
- Belongs to the NOSIP family.
Function for NOSIP Gene
Molecular function for NOSIP Gene
- UniProtKB/Swiss-Prot Function:
- E3 ubiquitin-protein ligase that is essential for proper development of the forebrain, the eye, and the face. Catalyzes monoubiquitination of serine/threonine-protein phosphatase 2A (PP2A) catalytic subunit PPP2CA/PPP2CB (By similarity). Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity (PubMed:11149895, PubMed:15548660, PubMed:16135813).
- UniProtKB/Swiss-Prot CatalyticActivity:
- Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.; EC=2.3.2.27;.
Enzyme Numbers (IUBMB) for NOSIP Gene
Phenotypes From GWAS Catalog for NOSIP Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003723 | RNA binding | HDA | 22658674 |
| GO:0004842 | ubiquitin-protein transferase activity | IEA | -- |
| GO:0005515 | protein binding | IPI | 11149895 |
| GO:0016740 | transferase activity | IEA | -- |
| GO:0061630 | ubiquitin protein ligase activity | IEA | -- |
Phenotypes for NOSIP Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for NOSIP - Select products 50% OFF >
- * NOSIP CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for NOSIP
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for NOSIP
-
Santa Cruz Biotechnology (SCBT) CRISPR for NOSIP
miRNA for NOSIP Gene
- miRTarBase miRNAs that target NOSIP
-
- hsa-miR-193b-3p (MIRT016289)
- hsa-miR-124-3p (MIRT022321)
- hsa-miR-218-5p (MIRT440102)
- mmu-miR-665-3p (MIRT586456)
- mmu-miR-706 (MIRT586457)
- mmu-miR-10a-5p (MIRT586458)
- mmu-miR-10b-5p (MIRT586459)
- mmu-miR-339-5p (MIRT586460)
- mmu-miR-1965 (MIRT598008)
- mmu-miR-1946a (MIRT598009)
- mmu-miR-5111-3p (MIRT598010)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for NOSIP
- Browse OriGene Inhibitory RNA Products For NOSIP
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NOSIP
Clone Products
- Applied Biological Materials (abm): Clones for NOSIP - Select products 50% OFF >
- * NOSIP as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for NOSIP
- Addgene plasmids for NOSIP
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for NOSIP
Cell Line Products
-
Horizon Cell Lines for NOSIP
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for NOSIP Gene
Localization for NOSIP Gene
Subcellular locations from UniProtKB/Swiss-Prot for NOSIP Gene
- Cytoplasm. Nucleus. Note=Translocates from nucleus to cytoplasm in the G2 phase of the cell cycle (PubMed:16135813).
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 4 |
| golgi apparatus | 4 |
| plasma membrane | 2 |
| extracellular | 2 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
| peroxisome | 0 |
- Nucleoplasm (4)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | -- |
| GO:0005634 | nucleus | IBA,IDA | 15548660 |
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0005737 | cytoplasm | IEA,IDA | 15548660 |
| GO:0005829 | cytosol | TAS | -- |
Pathways & Interactions for NOSIP Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | eNOS activation and regulation | ||
| 2 | Nanog in Mammalian ESC Pluripotency |
eNOS Signaling
.48
|
|
| 3 | Metabolism |
.40
|
|
Pathways by source for NOSIP Gene
4 Reactome pathways for NOSIP Gene
1 Qiagen pathway for NOSIP Gene
- eNOS Signaling
Interacting Proteins for NOSIP Gene
Selected Interacting proteins:
Q9Y314-NOSIP_HUMAN
ENSP00000470034
for NOSIP Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for NOSIP
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007275 | multicellular organism development | IEA | -- |
| GO:0016567 | protein ubiquitination | IEA | -- |
| GO:0043086 | negative regulation of catalytic activity | IDA | 11149895 |
| GO:0050999 | regulation of nitric-oxide synthase activity | TAS | -- |
| GO:0051001 | negative regulation of nitric-oxide synthase activity | IDA | 11149895 |
No data available for SIGNOR curated interactions for NOSIP Gene
Transcripts for NOSIP Gene
mRNA/cDNA for NOSIP Gene
- 3 REFSEQ mRNAs :
- 12 NCBI additional mRNA sequence :
- 16 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000339093 1000 nts (view in UCSC)
- ENST00000593345 933 nts (view in UCSC)
- ENST00000594932 602 nts (view in UCSC)
- ENST00000596358 1232 nts (view in UCSC)
- ENST00000596477 865 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for NOSIP - Select products 50% OFF >
- * NOSIP CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for NOSIP
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for NOSIP
-
Santa Cruz Biotechnology (SCBT) CRISPR for NOSIP
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for NOSIP
- Browse OriGene Inhibitory RNA Products For NOSIP
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NOSIP
Clone Products
- Applied Biological Materials (abm): Clones for NOSIP - Select products 50% OFF >
- * NOSIP as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for NOSIP
- Addgene plasmids for NOSIP
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for NOSIP
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | |||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||
| SP7: | |||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | - | |||||||||||||||||||||||||||||||||||||
| SP9: | - | ||||||||||||||||||||||||||||||||||||||||
| SP10: | - | - |
Relevant External Links for NOSIP Gene
- GeneLoc Exon Structure for
- NOSIP
Expression for NOSIP Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Hematopoietic System)
- T Helper Cells Peripheral Blood
- T-Cytotoxic Cells Peripheral Blood
-
Testis (Reproductive System)
mRNA differential expression in normal tissues according to GTEx for NOSIP Gene
This gene is overexpressed in Whole Blood (x4.3).
This gene is overexpressed in Breast (43.4) and Lymph node (7.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for NOSIP Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for NOSIP
SOURCE GeneReport for Unigene cluster for NOSIP Gene:
Hs.7236mRNA Expression by UniProt/SwissProt for NOSIP Gene:
Q9Y314-NOSIP_HUMAN
Tissue specificity:
Expressed in heart, brain and lung. Present in endothelial cells (at protein level).
Evidence on tissue expression from TISSUES for NOSIP Gene
- Nervous system(4.7)
- Liver(4.6)
- Lung(3.3)
- Muscle(2.8)
- Heart(2.5)
- Skin(2.4)
- Eye(2.2)
- Blood(2.1)
- Kidney(2.1)
- Intestine(2.1)
Primer Products
-
OriGene qPCR primer pairs for NOSIP
-
OriGene qPCR primer pairs and template standards for NOSIP
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for NOSIP Gene
Orthologs for NOSIP Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | NOSIP 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | NOSIP 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | NOSIP 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Nosip 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Nosip 30 17 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
| -- 31 |
|
OneToMany | |||
| Oppossum (Monodelphis domestica) |
Mammalia | NOSIP 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | NOSIP 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | nosip 30 |
|
||
| MGC75989 30 |
|
||||
| Zebrafish (Danio rerio) |
Actinopterygii | nosip 30 31 |
|
OneToOne | |
| -- 30 |
|
||||
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG6179 30 31 32 |
|
OneToOne | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP005654 30 |
|
||
| Worm (Caenorhabditis elegans) |
Secernentea | R05G6.4 30 31 |
|
OneToOne | |
| Thale Cress (Arabidopsis thaliana) |
eudicotyledons | AT1G61620 30 |
|
||
| Rice (Oryza sativa) |
Liliopsida | Os03g0279900 30 |
|
||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToOne |
- Species where no ortholog for NOSIP was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for NOSIP Gene
- ENSEMBL:
- Gene Tree for NOSIP (if available)
- TreeFam:
- Gene Tree for NOSIP (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for NOSIP: view image
Paralogs for NOSIP Gene
No data available for Paralogs for NOSIP Gene
Variants for NOSIP Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for NOSIP Gene
| SNP ID | Clinical significance and condition | Chr 19 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs17850728 | - | p.Thr168Met |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1160655 | CNV | deletion | 26073780 |
| nsv469715 | CNV | gain+loss | 16826518 |
| nsv828578 | CNV | loss | 20364138 |
| nsv833862 | CNV | loss | 17160897 |
| nsv833863 | CNV | loss | 17160897 |
| nsv833864 | CNV | gain | 17160897 |
| nsv833865 | CNV | gain+loss | 17160897 |
| nsv953600 | CNV | deletion | 24416366 |
| nsv9739 | CNV | gain+loss | 18304495 |
Residual Variation Intolerance Score:
26.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.42;
9.29% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for NOSIP Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- NOSIP
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NOSIP Gene
Disorders for NOSIP Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| polyomavirus-associated nephropathy |
|
|
Search NOSIP in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for NOSIP
No data available for UniProtKB/Swiss-Prot and Genatlas for NOSIP Gene
Publications for NOSIP Gene
- Cell cycle-regulated inactivation of endothelial NO synthase through NOSIP-dependent targeting to the cytoskeleton. (PMID: 16135813) Schleicher M … Oess S (Molecular and cellular biology 2005) 3 4 23
- NOSIP, a novel modulator of endothelial nitric oxide synthase activity. (PMID: 11149895) Dedio J … Müller-Esterl W (FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001) 2 3 4
- Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PMID: 10810093) Lai CH … Lin W (Genome research 2000) 2 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- Nitric oxide synthase (NOS)-interacting protein interacts with neuronal NOS and regulates its distribution and activity. (PMID: 15548660) Dreyer J … Kuner R (The Journal of neuroscience : the official journal of the Society for Neuroscience 2004) 3 4
ExternalLinks
Products for NOSIP Gene
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
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- Origene Custom Protein Services for NOSIP
- Origene shrna, sirna, and RNAi products in human, mouse, rat for NOSIP
- Browse OriGene Inhibitory RNA Products For NOSIP
- OriGene qPCR primer pairs for NOSIP
- OriGene qPCR primer pairs and template standards for NOSIP
- OriGene CRISPR knockouts for NOSIP
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For NOSIP
- Sino Biological Human cDNA Clone for NOSIP
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
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- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for NOSIP
- Novus Biologicals proteins and lysates for NOSIP
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for NOSIP
- Abcam proteins for NOSIP
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for NOSIP (AFLGC-NOSIP)
- VectorBuilder Custom and pre-made DNA vectors for NOSIP (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for NOSIP (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for NOSIP (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for NOSIP CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for NOSIP
- Addgene plasmids for NOSIP
- antibodies-online: Show 20 available NOSIP Antibodies ranked by validation data
- Compare Top NOSIP Antibodies
- antibodies-online: Show 10 available NOSIP Elisa Kits ranked by validation data
- Compare Top NOSIP Elisa Kits
- Quality Products:
- antibodies-online: Show 10 available NOSIP Proteins ranked by validation data
- Compare Top NOSIP Proteins
- Quality Products:
- Santa Cruz Biotechnology (SCBT) Antibodies for NOSIP
- Search Santa Cruz Biotechnology (SCBT) for NOSIP siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for NOSIP
- Horizon Cell Lines for NOSIP
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for NOSIP
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for NOSIP
- Search GeneCopoeia for miRNA 3'UTR Target clone products for NOSIP
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NOSIP
Sources for NOSIP Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
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