Aliases for NOP56 Gene
External Ids for NOP56 Gene
Previous HGNC Symbols for NOP56 Gene
Previous GeneCards Identifiers for NOP56 Gene
Nop56p is a yeast nucleolar protein that is part of a complex with the nucleolar proteins Nop58p and fibrillarin. Nop56p is required for assembly of the 60S ribosomal subunit and is involved in pre-rRNA processing. The protein encoded by this gene is similar in sequence to Nop56p and is also found in the nucleolus. Expansion of a GGCCTG repeat from 3-8 copies to 1500-2500 copies in an intron of this gene results in spinocerebellar ataxia 36. Multiple transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of most of them has not been determined. [provided by RefSeq, Jul 2016]
GeneCards Summary for NOP56 Gene
NOP56 (NOP56 Ribonucleoprotein) is a Protein Coding gene. Diseases associated with NOP56 include Spinocerebellar Ataxia 36 and Oromandibular Dystonia. Among its related pathways are rRNA processing in the nucleus and cytosol and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include snoRNA binding.
UniProtKB/Swiss-Prot for NOP56 Gene
Involved in the early to middle stages of 60S ribosomal subunit biogenesis. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs.