Aliases for NOL6 Gene
External Ids for NOL6 Gene
Previous GeneCards Identifiers for NOL6 Gene
The nucleolus is a dense subnuclear membraneless organelle that assembles around clusters of rRNA genes and functions in ribosome biogenesis. This gene encodes a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. Alternative splicing has been observed at this locus and two splice variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for NOL6 Gene
NOL6 (Nucleolar Protein 6) is a Protein Coding gene. Diseases associated with NOL6 include Autosomal Dominant Non-Syndromic Intellectual Disability 1 and Autosomal Dominant Non-Syndromic Intellectual Disability. Among its related pathways are rRNA processing in the nucleus and cytosol and Ribosome biogenesis in eukaryotes. Gene Ontology (GO) annotations related to this gene include RNA binding.