Aliases for NNT-AS1 Gene

Data sources for NNT-AS1 Gene:

RNA type for NNT-AS1 Gene

lncRNA

Aliases for NNT-AS1 Gene

External Ids for NNT-AS1 Gene

Previous GeneCards Identifiers for NNT-AS1 Gene

  • GC05M043572
  • GC05M043603
  • GC05M043634

Summaries for NNT-AS1 Gene

GeneCards Summary for NNT-AS1 Gene

NNT-AS1 (NNT Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with NNT-AS1 include Cervical Cancer and Osteogenic Sarcoma.

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for NNT-AS1 Gene

Genomics for NNT-AS1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for NNT-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH05J043601 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas 264.7 +1.0 1032 3.8 IKZF1 MYC ZNF592 POLR2A ZIC2 ZBTB10 YY1 MXD4 SMAD5 BHLHE40 NNT-AS1 NNT TMEM267 RPL29P12 ZNF131 EEF1A1P19 CCL28 FGF10
GH05J043553 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 12.2 +47.9 47854 4.6 IKZF1 MYC ZNF600 ZNF580 ZNF592 POLR2A BRCA1 NFIC ZBTB10 NONO PAIP1 RF00017-4151 NNT ENSG00000248240 C5orf34 EEF1A1P19 NNT-AS1 RPL29P12 ENSG00000249492 FGF10-AS1
GH05J043631 Enhancer 1 Ensembl ENCODE dbSUPER 23.9 -27.4 -27375 0.9 ZNF654 MYC YY1 REST TRIM22 CTCF MAX SIN3A RAD21 RFX5 NNT-AS1 NNT HSALNG0041524 MK280144-549 FGF10
GH05J043635 Enhancer 0.8 Ensembl ENCODE dbSUPER 25.1 -31.2 -31200 2.7 SP1 CEBPB HLF RXRA CEBPG NNT-AS1 NNT HSALNG0041524 MK280144-549 FGF10
GH05J043771 Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 12.3 -169.0 -169046 3.2 JUND ZNF592 NFIC CEBPB MAX ARNT EP300 RFX5 TAL1 ELF1 HSALNG0041529 TMEM267 ZNF131 NNT-AS1 ENSG00000249492 PAIP1 FGF10-AS1 NNT piR-56883-140 FGF10
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around NNT-AS1 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for NNT-AS1 Gene

Latest Assembly
chr5:43,571,320-43,603,954
(GRCh38/hg38)
Size:
32,635 bases
Orientation:
Minus strand

Previous Assembly
chr5:43,573,287-43,603,332
(GRCh37/hg19 by Entrez Gene)
Size:
30,046 bases
Orientation:
Minus strand

chr5:43,571,696-43,603,332
(GRCh37/hg19 by Ensembl)
Size:
31,637 bases
Orientation:
Minus strand

Genomic View for NNT-AS1 Gene

Genes around NNT-AS1 on UCSC Golden Path with GeneCards custom track
NNT-AS1 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
NNT-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NNT-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NNT-AS1 Gene

Proteins for NNT-AS1 Gene

Post-translational modifications for NNT-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for NNT-AS1 Gene

Domains & Families for NNT-AS1 Gene

Gene Families for NNT-AS1 Gene

genes like me logo Genes that share domains with NNT-AS1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for NNT-AS1 Gene

Function for NNT-AS1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NNT-AS1 Gene

Localization for NNT-AS1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for NNT-AS1 gene
Compartment Confidence
cytoskeleton 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for NNT-AS1 Gene

Pathways & Interactions for NNT-AS1 Gene

PathCards logo

SuperPathways for NNT-AS1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for NNT-AS1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for NNT-AS1 Gene

Drugs & Compounds for NNT-AS1 Gene

No Compound Related Data Available

Transcripts for NNT-AS1 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for NNT-AS1 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS0000443205_9606 lncRNA 581 4

Ensembl: ENST00000506247 (view in UCSC) ,

LncBook: HSALNT0087296,

LNCipedia: NNT-AS1:1,

NONCODE: NONHSAT101325.2,

URS00002FA790_9606 lncRNA 557 4

Ensembl: ENST00000515466 (view in UCSC) ,

LncBook: HSALNT0087290,

LNCipedia: NNT-AS1:3,

NONCODE: NONHSAT101322.2,

URS000075C8F1_9606 lncRNA 3304 3

RefSeq: NR_073113,

LNCipedia: NNT-AS1:2,

NONCODE: NONHSAT101321.2,

URS000035AC9C_9606 lncRNA 457 3

Ensembl: ENST00000500258 (view in UCSC) ,

LNCipedia: NNT-AS1:7,

NONCODE: NONHSAT101324.2,

URS000017EF87_9606 lncRNA 1948 2

Ensembl: ENST00000606697 (view in UCSC) ,

LNCipedia: NNT-AS1:8,

NNT-AS1 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for NNT-AS1 Gene

6 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for NNT-AS1 Gene

No ASD Table

Relevant External Links for NNT-AS1 Gene

GeneLoc Exon Structure for
NNT-AS1

Expression for NNT-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for NNT-AS1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for NNT-AS1

genes like me logo Genes that share expression patterns with NNT-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NNT-AS1 Gene

Orthologs for NNT-AS1 Gene

Evolution for NNT-AS1 Gene

ENSEMBL:
Gene Tree for NNT-AS1 (if available)
TreeFam:
Gene Tree for NNT-AS1 (if available)
Alliance of Genome Resources:
Additional Orthologs for NNT-AS1

No data available for Orthologs for NNT-AS1 Gene

Paralogs for NNT-AS1 Gene

No data available for Paralogs for NNT-AS1 Gene

Variants for NNT-AS1 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for NNT-AS1 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for NNT-AS1 Gene

Variant ID Type Subtype PubMed ID
esv2671038 CNV deletion 23128226
esv3604904 CNV gain 21293372
esv3604909 CNV loss 21293372
nsv830275 CNV gain 17160897
nsv980640 CNV duplication 23825009

Additional Variant Information for NNT-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
NNT-AS1
Leiden Open Variation Database (LOVD)
NNT-AS1

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for NNT-AS1 Gene

Disorders for NNT-AS1 Gene

MalaCards: The human disease database

(6) MalaCards diseases for NNT-AS1 Gene - From: LNC, COP, and GCD

Disorder Aliases PubMed IDs
cervical cancer
  • cervical cancer, somatic
osteogenic sarcoma
  • osteosarcoma; osrc
ovarian cancer
  • ovarian cancer, somatic
hepatocellular carcinoma
  • hcc
breast cancer
  • breast cancer, familial
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for NNT-AS1

genes like me logo Genes that share disorders with NNT-AS1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for NNT-AS1 Gene

Publications for NNT-AS1 Gene

  1. Upregulated NNT-AS1, a long noncoding RNA, contributes to proliferation and migration of colorectal cancer cells in vitro and in vivo. (PMID: 27966450) Wang Q … Feng G (Oncotarget 2017) 2 3 72
  2. Highly expressed long non-coding RNA NNT-AS1 promotes cell proliferation and invasion through Wnt/β-catenin signaling pathway in cervical cancer. (PMID: 28628975) Hua F … Yang J (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017) 2 3 72
  3. Overexpression of Long Non-Coding RNA NNT-AS1 Correlates with Tumor Progression and Poor Prognosis in Osteosarcoma. (PMID: 29518771) Ye H … Lu H (Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018) 3 72
  4. Long non-coding RNA NNT-AS1 affects progression of breast cancer through miR-142-3p/ZEB1 axis. (PMID: 29710510) Li Y … Zhuang M (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018) 3 72
  5. Long noncoding RNA NNT-AS1 promotes hepatocellular carcinoma progression and metastasis through miR-363/CDK6 axis. (PMID: 29179477) Lu YB … Zhang Q (Oncotarget 2017) 3 72

Products for NNT-AS1 Gene

Sources for NNT-AS1 Gene