Free for academic non-profit institutions. Other users need a Commercial license
N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. This gene encodes the protein responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor. [provided by RefSeq, Jul 2008] See more...
Aliases for NNMT Gene
External Ids for NNMT Gene
- HGNC: 7861
- NCBI Entrez Gene: 4837
- Ensembl: ENSG00000166741
- OMIM®: 600008
- UniProtKB/Swiss-Prot: P40261
Previous GeneCards Identifiers for NNMT Gene
- GC11P116520
- GC11P115640
- GC11P114162
- GC11P113666
- GC11P113633
- GC11P110095
Summaries for NNMT Gene
-
N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. This gene encodes the protein responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor. [provided by RefSeq, Jul 2008]
GeneCards Summary for NNMT Gene
NNMT (Nicotinamide N-Methyltransferase) is a Protein Coding gene. Diseases associated with NNMT include Pellagra and Phototoxic Dermatitis. Among its related pathways are Viral mRNA Translation and NAD metabolism. Gene Ontology (GO) annotations related to this gene include methyltransferase activity and nicotinamide N-methyltransferase activity. An important paralog of this gene is INMT.
UniProtKB/Swiss-Prot Summary for NNMT Gene
-
Catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions. This activity is important for biotransformation of many drugs and xenobiotic compounds.
Additional gene information for NNMT Gene
- HGNC (7861)
- NCBI Entrez Gene (4837)
- Ensembl (ENSG00000166741)
- OMIM® (600008)
- UniProtKB/Swiss-Prot (P40261)
- Open Targets Platform(ENSG00000166741)
- Search for NNMT at DataMed
- Search for NNMT at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for NNMT Gene
Genomics for NNMT Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for NNMT Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around NNMT on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for NNMT
- Top Transcription factor binding sites by QIAGEN in the NNMT gene promoter:
-
- Brachyury
- FOXC1
- GATA-1
- GATA-2
- GATA-3
- HNF-3beta
- SEF-1 (1)
- STAT6
Genomic Locations for NNMT Gene
Latest Assembly
- chr11:114,257,787-114,313,536
- (GRCh38/hg38)
- Size:
- 55,750 bases
- Orientation:
- Plus strand
Previous Assembly
- chr11:114,128,528-114,184,258
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 55,731 bases
- Orientation:
- Plus strand
- chr11:114,128,509-114,184,007
- (GRCh37/hg19 by Ensembl)
- Size:
- 55,499 bases
- Orientation:
- Plus strand
Genomic View for NNMT Gene
Genes around NNMT on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q23.2 by HGNC
- 11q23.2 by Entrez Gene
- 11q23.2 by Ensembl
NNMT Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for NNMT Gene
Proteins for NNMT Gene
-
Protein details for NNMT Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P40261-NNMT_HUMAN
- Recommended name:
- Nicotinamide N-methyltransferase
- Protein Accession:
- P40261
Protein attributes for NNMT Gene
- Size:
- 264 amino acids
- Molecular mass:
- 29574 Da
- Quaternary structure:
-
- Monomer.
Protein Expression for NNMT Gene
Post-translational modifications for NNMT Gene
Other Protein References for NNMT Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- LifeSpan BioSciences NNMT Monoclonal Antibody (LS-B12938) and NNMT Monoclonal Antibody (LS-B12974)
- Novus Biologicals Antibodies for NNMT
-
Abcam antibodies for NNMT
- Invitrogen Antibodies for NNMT (AFLGC-NNMT)
-
Boster Bio Antibodies for NNMT
-
Custom Antibody ServicesProSci Antibodies for NNMT
- nicotinamide N-methyltransferase [15-330]
- nicotinamide N-methyltransferase [18-221]
- nicotinamide N-methyltransferase [22-396]
- nicotinamide N-methyltransferase [43-628]
- nicotinamide N-methyltransferase [43-640]
- nicotinamide N-methyltransferase [29-728]
- Nicotinamide N-methyltransferase [55-106]
- Nicotinamide N-methyltransferase [57-263]
-
Santa Cruz Biotechnology (SCBT) Antibodies for NNMT
Protein products for research
- Search Origene for MassSpec and Protein Over-expression Lysates for NNMT
- Origene Custom Protein Services for NNMT
- ProSpec Recombinant Proteins for NNMT
-
Abcam proteins for NNMT
Assay products for research
- antibodies-online: Show 20 available NNMT Elisa Kits ranked by validation data
- Compare Top NNMT Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for NNMT Gene
Domains & Families for NNMT Gene
Gene Families for NNMT Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Enzymes
- FDA approved drug targets
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for NNMT Gene
- InterPro:
- Blocks:
-
- Methyltransferase, NNMT/PNMT/TEMT family
- ProtoNet:
Suggested Antigen Peptide Sequences for NNMT Gene
- GenScript: Design optimal peptide antigens:
-
- Nicotinamide N-methyltransferase (NNMT_HUMAN)
- Nicotinamide N-methyltransferase, isoform CRA_a (Q6FH49_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P40261UniProtKB/Swiss-Prot:
NNMT_HUMAN :- Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.
- Family:
-
- Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.
Function for NNMT Gene
Molecular function for NNMT Gene
- UniProtKB/Swiss-Prot Function:
- Catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions. This activity is important for biotransformation of many drugs and xenobiotic compounds.
- UniProtKB/Swiss-Prot CatalyticActivity:
- Reaction=nicotinamide + S-adenosyl-L-methionine = 1-methylnicotinamide + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:23884, ChEBI:CHEBI:16797, ChEBI:CHEBI:17154, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789; EC=2.1.1.1;.
- GENATLAS Biochemistry:
- nicotinamide N-methyltransferase
Enzyme Numbers (IUBMB) for NNMT Gene
Phenotypes From GWAS Catalog for NNMT Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0008112 | nicotinamide N-methyltransferase activity | TAS | -- |
| GO:0008168 | methyltransferase activity | IEA | -- |
| GO:0008170 | N-methyltransferase activity | IBA | 21873635 |
| GO:0016740 | transferase activity | IEA | -- |
| GO:0030760 | pyridine N-methyltransferase activity | TAS | -- |
Phenotypes for NNMT Gene
- MGI mutant phenotypes for NNMT:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for NNMT:
-
- Increased vaccinia virus (VACV) infection
- Decreased viability
- no effect
- shRNA abundance <= 25%
- Increased number of cells in monopolar arrest with EMD534085 (a Kinesin-5 inhibitor)
- Decreased interferon-beta reporter expression
- Decreased viability with paclitaxel
- Decreased viability in non-small-cell lung cancer (NSCLC) lineage; decreased viability in pancreas lineage
Animal Models for research
-
Taconic Biosciences Mouse Models for NNMT
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for NNMT - Starting at $85 >
- * NNMT CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for NNMT
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for NNMT
-
Santa Cruz Biotechnology (SCBT) CRISPR for NNMT
miRNA for NNMT Gene
- miRTarBase miRNAs that target NNMT
-
- hsa-miR-124-3p (MIRT022959)
- hsa-miR-98-5p (MIRT027710)
- hsa-miR-1304-5p (MIRT689984)
- hsa-miR-6765-5p (MIRT689985)
- hsa-miR-6086 (MIRT689986)
- hsa-miR-377-5p (MIRT689987)
- hsa-miR-4433a-3p (MIRT689988)
- hsa-miR-4459 (MIRT689989)
- hsa-miR-4768-3p (MIRT689990)
- hsa-miR-6500-3p (MIRT689991)
- hsa-miR-3614-5p (MIRT689992)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for NNMT
- Browse OriGene Inhibitory RNA Products For NNMT
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NNMT
Clone products for research
- Applied Biological Materials (abm): Clones for NNMT - Starting at $45 >
- * NNMT as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for NNMT
- Addgene plasmids for NNMT
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for NNMT
Cell Lines for research
-
Horizon Cell Lines for NNMT
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for NNMT Gene
Localization for NNMT Gene
Subcellular locations from UniProtKB/Swiss-Prot for NNMT Gene
- Cytoplasm.
| Compartment | Confidence |
|---|---|
| cytosol | 4 |
| nucleus | 3 |
| extracellular | 2 |
| mitochondrion | 2 |
| plasma membrane | 1 |
| cytoskeleton | 1 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
| lysosome | 1 |
- Cytosol (3)
- Golgi apparatus (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005829 | cytosol | IEA,TAS | -- |
Pathways & Interactions for NNMT Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | NAD metabolism |
NAD metabolism
.53
|
|
| 2 | Cytochrome P450 - arranged by substrate type |
.01
|
|
| 3 | Viral mRNA Translation | ||
| 4 | Metabolism |
.40
|
|
| 5 | Metabolism of water-soluble vitamins and cofactors | ||
Pathways by source for NNMT Gene
2 BioSystems pathways for NNMT Gene
2 KEGG pathways for NNMT Gene
1 GeneGo (Thomson Reuters) pathway for NNMT Gene
- NAD metabolism
Interacting Proteins for NNMT Gene
GPS-Prot Interaction Network for NNMT
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0010243 | response to organonitrogen compound | IEA | -- |
| GO:0031100 | animal organ regeneration | IEA | -- |
| GO:0032259 | methylation | TAS | -- |
| GO:0034356 | NAD biosynthesis via nicotinamide riboside salvage pathway | TAS | -- |
| GO:0042493 | response to drug | IEA | -- |
No data available for SIGNOR curated interactions for NNMT Gene
Drugs & Compounds for NNMT Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| s-adenosylmethionine |
|
485-80-3 | ||||
| 1-Methylnicotinamide |
|
3106-60-3 |
|
|||
| Hydrogen Ion |
|
|
Transcripts for NNMT Gene
mRNA/cDNA for NNMT Gene
- 4 REFSEQ mRNAs :
- 6 NCBI additional mRNA sequence :
- 8 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000299964 2012 nts (view in UCSC)
- ENST00000535185 379 nts (view in UCSC)
- ENST00000535401 1867 nts (view in UCSC)
- ENST00000541090 351 nts (view in UCSC)
- ENST00000541754 716 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for NNMT - Starting at $85 >
- * NNMT CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for NNMT
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for NNMT
-
Santa Cruz Biotechnology (SCBT) CRISPR for NNMT
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for NNMT
- Browse OriGene Inhibitory RNA Products For NNMT
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NNMT
Clone products for research
- Applied Biological Materials (abm): Clones for NNMT - Starting at $45 >
- * NNMT as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for NNMT
- Addgene plasmids for NNMT
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for NNMT
Relevant External Links for NNMT Gene
- GeneLoc Exon Structure for
- NNMT
Expression for NNMT Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Endothelium (Cardiovascular System)
-
Liver (Hepatobiliary System)
- Hepatocytes Liver Lobule
-
Testis (Reproductive System)
- Mature Sertoli Cells Seminiferous Tubules
- Heart (Cardiovascular System)
- Dermis (Integumentary System)
- Fibroblasts
- NULL (Uncategorized)
-
Placenta (Extraembryonic Tissues)
-
Spleen (Hematopoietic System)
-
Gall Bladder (Hepatobiliary System)
-
Lung (Respiratory System)
-
Bone (Muscoskeletal System)
-
Adipose (Muscoskeletal System)
mRNA differential expression in normal tissues according to GTEx for NNMT Gene
This gene is overexpressed in Liver (x13.7).
This gene is overexpressed in Liver (15.2) and Liver, secretome (7.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for NNMT Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for NNMT
SOURCE GeneReport for Unigene cluster for NNMT Gene:
Hs.503911mRNA Expression by UniProt/SwissProt for NNMT Gene:
P40261-NNMT_HUMAN
Tissue specificity:
Predominantly expressed in the liver. A lower expression is seen in the kidney, lung, skeletal muscle, placenta and heart. Not detected in the brain or pancreas.
Evidence on tissue expression from TISSUES for NNMT Gene
- Liver(5)
- Eye(4.3)
- Bone(3.3)
- Lung(3.1)
- Kidney(3)
- Nervous system(2.9)
- Intestine(2.9)
- Muscle(2.5)
- Skin(2.3)
- Heart(2.2)
- Lymph node(2.2)
- Pancreas(2.2)
- Gall bladder(2.1)
Primer products for research
-
OriGene qPCR primer pairs for NNMT
-
OriGene qPCR primer pairs and template standards for NNMT
Gene Expression Assays for research
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for NNMT Gene
Orthologs for NNMT Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | NNMT 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | NNMT 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Nnmt 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Nnmt 30 17 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | NNMT 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | NNMT 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | -- 31 |
|
ManyToMany | |
| Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
ManyToMany | |
| -- 31 |
|
ManyToMany | |||
| -- 31 |
|
ManyToMany | |||
| -- 31 |
|
ManyToMany | |||
| -- 31 |
|
ManyToMany | |||
| -- 31 |
|
ManyToMany | |||
| -- 31 |
|
ManyToMany | |||
| -- 31 |
|
ManyToMany | |||
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | LOC100127789 30 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | MGC69005 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | zgc:64002 31 31 |
|
ManyToMany | |
| Worm (Caenorhabditis elegans) |
Secernentea | anmt-2 31 |
|
ManyToMany | |
| anmt-1 31 |
|
ManyToMany | |||
| anmt-3 31 |
|
ManyToMany |
- Species where no ortholog for NNMT was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for NNMT Gene
- ENSEMBL:
- Gene Tree for NNMT (if available)
- TreeFam:
- Gene Tree for NNMT (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for NNMT: view image
Paralogs for NNMT Gene
(3) SIMAP similar genes for NNMT Gene using alignment to 3 proteins:
- NNMT_HUMAN
- F5H0R4_HUMAN
- Q6FH49_HUMAN
Pseudogenes.org Pseudogenes for NNMT Gene
Variants for NNMT Gene
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3360369 | CNV | duplication | 20981092 |
Residual Variation Intolerance Score:
52.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.86;
17.88% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for NNMT Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- NNMT
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for NNMT Gene
Disorders for NNMT Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| pellagra |
|
|
| phototoxic dermatitis |
|
|
| parkinson disease, late-onset |
|
|
| lung cancer |
|
|
| renal cell carcinoma, nonpapillary |
|
|
Search NNMT in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for NNMT
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for NNMT Gene
Publications for NNMT Gene
- Human nicotinamide N-methyltransferase gene: molecular cloning, structural characterization and chromosomal localization. (PMID: 8575745) Aksoy S … Weinshilboum RM (Genomics 1995) 2 3 4 23
- Polymorphisms in folate-related genes and risk of pediatric acute lymphoblastic leukemia. (PMID: 19020309) de Jonge R … Pieters R (Blood 2009) 3 23 41
- Adipose tissue as a source of nicotinamide N-methyltransferase and homocysteine. (PMID: 18996527) Riederer M … Zechner R (Atherosclerosis 2009) 3 23 26
- High-throughput multiplex single-nucleotide polymorphism (SNP) analysis in genes involved in methionine metabolism. (PMID: 18427977) Giusti B … Abbate R (Biochemical genetics 2008) 3 23 41
- Genetic analysis of 56 polymorphisms in 17 genes involved in methionine metabolism in patients with abdominal aortic aneurysm. (PMID: 18635682) Giusti B … Abbate R (Journal of medical genetics 2008) 3 23 41
ExternalLinks
Products for NNMT Gene
- View all 2 R&D Systems NNMT (Nicotinamide N-Methyltransferase/NNMT) Products
- View all R&D Systems NNMT (Nicotinamide N-Methyltransferase/NNMT) Proteins and Enzymes
- View all R&D Systems NNMT (Nicotinamide N-Methyltransferase/NNMT) Primary Antibodies
- Learn more about R&D Systems custom NNMT antibody, protein, and immunoassay development services
- Custom Antibody ServicesOriGene Antibodies for NNMT
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for NNMT
- Origene Custom Protein Services for NNMT
- Origene shrna, sirna, and RNAi products in human, mouse, rat for NNMT
- Browse OriGene Inhibitory RNA Products For NNMT
- OriGene qPCR primer pairs for NNMT
- OriGene qPCR primer pairs and template standards for NNMT
- OriGene CRISPR knockouts for NNMT
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For NNMT
- Sino Biological Human cDNA Clone for NNMT
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for NNMT
- Novus Biologicals proteins and lysates for NNMT
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for NNMT
- Abcam proteins for NNMT
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- ProSpec Recombinant Proteins for NNMT
- Taconic Biosciences Mouse Models for NNMT
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for NNMT (AFLGC-NNMT)
- VectorBuilder Custom and pre-made DNA vectors for NNMT (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for NNMT (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for NNMT (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for NNMT CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for NNMT
- Addgene plasmids for NNMT
- antibodies-online: Show 51 available NNMT Antibodies ranked by validation data
- Compare Top NNMT Antibodies
- antibodies-online: Show 20 available NNMT Elisa Kits ranked by validation data
- Compare Top NNMT Elisa Kits
- Quality Products:
- antibodies-online: Show 17 available NNMT Proteins ranked by validation data
- Compare Top NNMT Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for NNMT
- Search Santa Cruz Biotechnology (SCBT) for NNMT siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for NNMT
- Custom Antibody ServicesProSci Antibodies for NNMT
- nicotinamide N-methyltransferase [15-330]
- nicotinamide N-methyltransferase [18-221]
- nicotinamide N-methyltransferase [22-396]
- nicotinamide N-methyltransferase [43-628]
- nicotinamide N-methyltransferase [43-640]
- nicotinamide N-methyltransferase [29-728]
- Nicotinamide N-methyltransferase [55-106]
- Nicotinamide N-methyltransferase [57-263]
- Search for NNMT Proteins at ProSci
- Horizon Cell Lines for NNMT
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for NNMT
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for NNMT
- Search GeneCopoeia for miRNA 3'UTR Target clone products for NNMT
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NNMT
- Boster Bio Antibodies for NNMT
- Browse Boster Bio ELISA Kits
Sources for NNMT Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB