External Ids for NNMT Gene
Previous GeneCards Identifiers for NNMT Gene
N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. This gene encodes the protein responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor. [provided by RefSeq, Jul 2008]
GeneCards Summary for NNMT Gene
NNMT (Nicotinamide N-Methyltransferase) is a Protein Coding gene. Diseases associated with NNMT include Pellagra and Phototoxic Dermatitis. Among its related pathways are Viral mRNA Translation and NAD metabolism. Gene Ontology (GO) annotations related to this gene include methyltransferase activity and nicotinamide N-methyltransferase activity. An important paralog of this gene is INMT.
UniProtKB/Swiss-Prot Summary for NNMT Gene
Catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions. This activity is important for biotransformation of many drugs and xenobiotic compounds.