Aliases for NMUR2 Gene
External Ids for NMUR2 Gene
Previous HGNC Symbols for NMUR2 Gene
Previous GeneCards Identifiers for NMUR2 Gene
This gene encodes a protein from the G-protein coupled receptor 1 family. This protein is a receptor for neuromedin U, which is a neuropeptide that is widely distributed in the gut and central nervous system. This receptor plays an important role in the regulation of food intake and body weight. [provided by RefSeq, Jul 2008]
GeneCards Summary for NMUR2 Gene
NMUR2 (Neuromedin U Receptor 2) is a Protein Coding gene. Diseases associated with NMUR2 include Myasthenic Syndrome, Congenital, 4C, Associated With Acetylcholine Receptor Deficiency and Robinow Syndrome, Autosomal Dominant 2. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and neuropeptide receptor activity. An important paralog of this gene is NMUR1.
UniProtKB/Swiss-Prot Summary for NMUR2 Gene
Receptor for the neuromedin-U and neuromedin-S neuropeptides.
Neuromedin U (NMU) receptors are a group of Gq/11-protein-coupled receptors that are currently divided into two subtypes: NMU1 and NMU2. The two subtypes have distinct tissue distributions: NMU1 is expressed in the periphery, whilst NMU2 is expressed in the CNS.