Aliases for NMT2 Gene
External Ids for NMT2 Gene
Previous GeneCards Identifiers for NMT2 Gene
This gene encodes one of two N-myristoyltransferase proteins. N-terminal myristoylation is a lipid modification that is involved in regulating the function and localization of signaling proteins. The encoded protein catalyzes the addition of a myristoyl group to the N-terminal glycine residue of many signaling proteins, including the human immunodeficiency virus type 1 (HIV-1) proteins, Gag and Nef. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
GeneCards Summary for NMT2 Gene
NMT2 (N-Myristoyltransferase 2) is a Protein Coding gene. Diseases associated with NMT2 include Human Immunodeficiency Virus Type 1. Among its related pathways are Signaling by GPCR and Metabolism of fat-soluble vitamins. Gene Ontology (GO) annotations related to this gene include glycylpeptide N-tetradecanoyltransferase activity. An important paralog of this gene is NMT1.
UniProtKB/Swiss-Prot Summary for NMT2 Gene
Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins.