Aliases for NME5 Gene
External Ids for NME5 Gene
Previous GeneCards Identifiers for NME5 Gene
GeneCards Summary for NME5 Gene
NME5 (NME/NM23 Family Member 5) is a Protein Coding gene. Diseases associated with NME5 include Nemaline Myopathy 5 and Primary Ciliary Dyskinesia. Among its related pathways are superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis and purine nucleotides de novo biosynthesis. Gene Ontology (GO) annotations related to this gene include nucleoside diphosphate kinase activity. An important paralog of this gene is NME8.
UniProtKB/Swiss-Prot Summary for NME5 Gene
Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species (By similarity).