Aliases for NKTR Gene
External Ids for NKTR Gene
Previous GeneCards Identifiers for NKTR Gene
This gene encodes a membrane-anchored protein with a hydrophobic amino terminal domain and a cyclophilin-like PPIase domain. It is present on the surface of natural killer cells and facilitates their binding to targets. Its expression is regulated by IL2 activation of the cells. [provided by RefSeq, Jul 2008]
GeneCards Summary for NKTR Gene
NKTR (Natural Killer Cell Triggering Receptor) is a Protein Coding gene. Diseases associated with NKTR include Theileriasis and Opioid Abuse. Gene Ontology (GO) annotations related to this gene include peptidyl-prolyl cis-trans isomerase activity and cyclosporin A binding. An important paralog of this gene is PPIG.
UniProtKB/Swiss-Prot Summary for NKTR Gene
PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding (PubMed:20676357). Component of a putative tumor-recognition complex involved in the function of NK cells (PubMed:8421688).