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NKAIN1 is a member of a family of mammalian proteins with similarity to Drosophila Nkain and interacts with the beta subunit of Na,K-ATPase (ATP1B1; MIM 182330) (Gorokhova et al., 2007 [PubMed 17606467]).[supplied by OMIM, Jun 2009]
NKAIN1 (Sodium/Potassium Transporting ATPase Interacting 1) is a Protein Coding gene. An important paralog of this gene is NKAIN2.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0051117 | ATPase binding | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005886 | plasma membrane | IEA | -- |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0002028 | regulation of sodium ion transport | IBA | 21873635 |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | NKAIN1 33 32 |
|
OneToOne | |
cow (Bos Taurus) |
Mammalia | NKAIN1 33 32 |
|
OneToOne | |
dog (Canis familiaris) |
Mammalia | NKAIN1 33 32 |
|
OneToOne | |
oppossum (Monodelphis domestica) |
Mammalia | NKAIN1 33 |
|
OneToOne | |
mouse (Mus musculus) |
Mammalia | Nkain1 17 33 32 |
|
||
rat (Rattus norvegicus) |
Mammalia | Nkain1 32 |
|
||
platypus (Ornithorhynchus anatinus) |
Mammalia | NKAIN1 33 |
|
OneToOne | |
chicken (Gallus gallus) |
Aves | NKAIN1 33 32 |
|
OneToOne | |
tropical clawed frog (Silurana tropicalis) |
Amphibia | nkain1 32 |
|
||
African clawed frog (Xenopus laevis) |
Amphibia | Xl.24215 32 |
|
||
zebrafish (Danio rerio) |
Actinopterygii | nkain1 33 32 |
|
OneToOne | |
zgc65908 32 |
|
||||
fruit fly (Drosophila melanogaster) |
Insecta | NKAIN 33 |
|
OneToMany | |
sea squirt (Ciona savignyi) |
Ascidiacea | CSA.3479 33 |
|
OneToMany |
SNP ID | Clin | Chr 01 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1000064271 | -- | 31,205,045(-) | A/G/T | intron_variant | |
rs1000112137 | -- | 31,241,200(-) | C/T | upstream_transcript_variant | |
rs1000140596 | -- | 31,219,900(-) | G/A | intron_variant | |
rs1000262796 | -- | 31,200,089(-) | G/A | intron_variant | |
rs1000303693 | -- | 31,222,623(-) | C/T | intron_variant |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv21860 | CNV | loss | 19812545 |
esv2758930 | CNV | loss | 17122850 |
nsv1075384 | CNV | deletion | 25765185 |
nsv1126190 | CNV | deletion | 24896259 |
nsv1145331 | CNV | deletion | 24896259 |
nsv160707 | CNV | deletion | 16902084 |
nsv508711 | CNV | deletion | 20534489 |
No disorders were found for NKAIN1 Gene.