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This gene encodes a member of the NipSnap family of proteins that may be involved in vesicular transport. A similar protein in mice inhibits the calcium channel TRPV6, and is also localized to the inner mitochondrial membrane where it may play a role in mitochondrial DNA maintenance. A pseudogene of this gene is located on the short arm of chromosome 17. Alternatively spliced t... See more...
Aliases for NIPSNAP1 Gene
Aliases for NIPSNAP1 Gene
External Ids for NIPSNAP1 Gene
- HGNC: 7827
- NCBI Entrez Gene: 8508
- Ensembl: ENSG00000184117
- OMIM®: 603249
- UniProtKB/Swiss-Prot: Q9BPW8
Previous GeneCards Identifiers for NIPSNAP1 Gene
- GC22M026646
- GC22M028275
- GC22M029952
- GC22M012914
Summaries for NIPSNAP1 Gene
-
This gene encodes a member of the NipSnap family of proteins that may be involved in vesicular transport. A similar protein in mice inhibits the calcium channel TRPV6, and is also localized to the inner mitochondrial membrane where it may play a role in mitochondrial DNA maintenance. A pseudogene of this gene is located on the short arm of chromosome 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]
GeneCards Summary for NIPSNAP1 Gene
NIPSNAP1 (Nipsnap Homolog 1) is a Protein Coding gene. Diseases associated with NIPSNAP1 include Phenylketonuria and Fibrous Meningioma. Among its related pathways are Ca, cAMP and Lipid Signaling and Neuroscience. Gene Ontology (GO) annotations related to this gene include neurotransmitter binding. An important paralog of this gene is NIPSNAP2.
Additional gene information for NIPSNAP1 Gene
- HGNC (7827)
- NCBI Entrez Gene (8508)
- Ensembl (ENSG00000184117)
- OMIM® (603249)
- UniProtKB/Swiss-Prot (Q9BPW8)
- Open Targets Platform(ENSG00000184117)
- Monarch Initiative
- Alliance of Genome Resources
- Search for NIPSNAP1 at DataMed
- Search for NIPSNAP1 at HumanCyc
No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for NIPSNAP1 Gene
Genomics for NIPSNAP1 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for NIPSNAP1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around NIPSNAP1 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for NIPSNAP1
- Top Transcription factor binding sites by QIAGEN in the NIPSNAP1 gene promoter:
-
- AP-1
- STAT3
Genomic Locations for NIPSNAP1 Gene
Latest Assembly
- chr22:29,554,808-29,581,327
- (GRCh38/hg38)
- Size:
- 26,520 bases
- Orientation:
- Minus strand
Previous Assembly
- chr22:29,950,797-29,977,102
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 26,306 bases
- Orientation:
- Minus strand
Genomic View for NIPSNAP1 Gene
Genes around NIPSNAP1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 22q12.2 by HGNC
- 22q12.2 by Entrez Gene
- 22q12.2 by Ensembl
NIPSNAP1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for NIPSNAP1 Gene
Proteins for NIPSNAP1 Gene
-
Protein details for NIPSNAP1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9BPW8-NIPS1_HUMAN
- Recommended name:
- Protein NipSnap homolog 1
- Protein Accession:
- Q9BPW8
- B2RAY3
- O43800
Protein attributes for NIPSNAP1 Gene
- Size:
- 284 amino acids
- Molecular mass:
- 33310 Da
- Quaternary structure:
- No Data Available
Protein Expression for NIPSNAP1 Gene
Post-translational modifications for NIPSNAP1 Gene
Other Protein References for NIPSNAP1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- Novus Biologicals Antibodies for NIPSNAP1
-
Abcam antibodies for NIPSNAP1
- Invitrogen Antibodies for NIPSNAP1 (AFLGC-NIPSNAP1)
-
Boster Bio Antibodies for NIPSNAP1
-
Custom Antibody ServicesProSci Antibodies for NIPSNAP1
-
Santa Cruz Biotechnology (SCBT) Antibodies for NIPSNAP1
Protein products for research
-
OriGene Purified Proteins for NIPSNAP1
- Search Origene for MassSpec and Protein Over-expression Lysates for NIPSNAP1
- Origene Custom Protein Services for NIPSNAP1
- Novus Biologicals proteins for NIPSNAP1
- ProSpec Recombinant Proteins for NIPSNAP1
- antibodies-online: Show 6 available NIPSNAP1 Proteins ranked by validation data
- Compare Top NIPSNAP1 Proteins
-
Quality Products:
-
Abcam proteins for NIPSNAP1
Assay products for research
No data available for DME Specific Peptides for NIPSNAP1 Gene
Domains & Families for NIPSNAP1 Gene
Gene Families for NIPSNAP1 Gene
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for NIPSNAP1 Gene
- InterPro:
- Blocks:
-
- NIPSNAP
Suggested Antigen Peptide Sequences for NIPSNAP1 Gene
- GenScript: Design optimal peptide antigens:
-
- Protein NipSnap homolog 1 (NIPS1_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9BPW8- Family:
-
- Belongs to the NipSnap family.
Function for NIPSNAP1 Gene
Molecular function for NIPSNAP1 Gene
- GENATLAS Biochemistry:
- putative peroxisomal protein,involved in vesicular transport,member 1 of a new gene-family,homolog to a hypothetical protein (P34492) from C elegans
Phenotypes From GWAS Catalog for NIPSNAP1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 25126726 |
| GO:0042165 | neurotransmitter binding | IEA | -- |
Phenotypes for NIPSNAP1 Gene
- MGI mutant phenotypes for NIPSNAP1:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for NIPSNAP1:
Animal Models for NIPSNAP1 Gene
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for NIPSNAP1 - Starting at $85 >
- * NIPSNAP1 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for NIPSNAP1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for NIPSNAP1
-
Santa Cruz Biotechnology (SCBT) CRISPR for NIPSNAP1
miRNA for NIPSNAP1 Gene
- miRTarBase miRNAs that target NIPSNAP1
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for NIPSNAP1
- Browse OriGene Inhibitory RNA Products For NIPSNAP1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NIPSNAP1
Clone products for research
- Applied Biological Materials (abm): Clones for NIPSNAP1 - Starting at $45 >
- * NIPSNAP1 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for NIPSNAP1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for NIPSNAP1
Cell Lines for research
-
Horizon Cell Lines for NIPSNAP1
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for NIPSNAP1 Gene
Localization for NIPSNAP1 Gene
| Compartment | Confidence |
|---|---|
| mitochondrion | 5 |
| plasma membrane | 2 |
| extracellular | 1 |
| cytoskeleton | 1 |
| peroxisome | 1 |
| nucleus | 1 |
| endosome | 1 |
| cytosol | 1 |
| lysosome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005739 | mitochondrion | IEA,ISS | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0097060 | synaptic membrane | IEA | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for NIPSNAP1 Gene
Pathways & Interactions for NIPSNAP1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Ca, cAMP and Lipid Signaling | ||
| 2 | Neuroscience | ||
Pathways by source for NIPSNAP1 Gene
2 Cell Signaling Technology pathways for NIPSNAP1 Gene
Interacting Proteins for NIPSNAP1 Gene
Selected Interacting proteins:
Q9BPW8-NIPS1_HUMAN
ENSP00000216121
for NIPSNAP1 Gene via
MINT
STRING
IID
GPS-Prot Interaction Network for NIPSNAP1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0019233 | sensory perception of pain | IEA,IBA | 21873635 |
No data available for SIGNOR curated interactions for NIPSNAP1 Gene
Transcripts for NIPSNAP1 Gene
mRNA/cDNA for NIPSNAP1 Gene
- 2 REFSEQ mRNAs :
- 9 NCBI additional mRNA sequence :
- 6 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000216121 2013 nts (view in UCSC)
- ENST00000415100 661 nts (view in UCSC)
- ENST00000437094 674 nts (view in UCSC)
- ENST00000455496 600 nts (view in UCSC)
- ENST00000494966 441 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for NIPSNAP1 - Starting at $85 >
- * NIPSNAP1 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for NIPSNAP1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for NIPSNAP1
-
Santa Cruz Biotechnology (SCBT) CRISPR for NIPSNAP1
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for NIPSNAP1
- Browse OriGene Inhibitory RNA Products For NIPSNAP1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NIPSNAP1
Clone products for research
- Applied Biological Materials (abm): Clones for NIPSNAP1 - Starting at $45 >
- * NIPSNAP1 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for NIPSNAP1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for NIPSNAP1
Relevant External Links for NIPSNAP1 Gene
- GeneLoc Exon Structure for
- NIPSNAP1
Expression for NIPSNAP1 Gene
mRNA differential expression in normal tissues according to GTEx for NIPSNAP1 Gene
This gene is overexpressed in Liver (x5.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for NIPSNAP1 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for NIPSNAP1
SOURCE GeneReport for Unigene cluster for NIPSNAP1 Gene:
Hs.173878mRNA Expression by UniProt/SwissProt for NIPSNAP1 Gene:
Q9BPW8-NIPS1_HUMAN
Tissue specificity:
Ubiquitous. Highest expression in liver.
Evidence on tissue expression from TISSUES for NIPSNAP1 Gene
- Lung(4.5)
- Liver(4.5)
- Nervous system(4.4)
- Intestine(4.3)
- Eye(3.2)
- Kidney(2.4)
Primer products for research
-
OriGene qPCR primer pairs for NIPSNAP1
-
OriGene qPCR primer pairs and template standards for NIPSNAP1
Gene Expression Assays for research
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for NIPSNAP1 Gene
Orthologs for NIPSNAP1 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | NIPSNAP1 29 30 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | NIPSNAP1 29 30 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | NIPSNAP1 29 30 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Nipsnap1 29 |
|
||
| Mouse (Mus musculus) |
Mammalia | Nipsnap1 29 16 30 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | NIPSNAP1 30 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | mdo-mir-1546 30 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | NIPSNAP1 29 |
|
||
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | nipsnap1 29 |
|
||
| Str.15493 29 |
|
||||
| Zebrafish (Danio rerio) |
Actinopterygii | nipsnap1 29 30 |
|
OneToOne | |
| nipsnap2 29 |
|
||||
| Rainbow Trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.9741 29 |
|
||
| Fruit Fly (Drosophila melanogaster) |
Insecta | Nipsnap 30 31 |
|
OneToMany | |
| Worm (Caenorhabditis elegans) |
Secernentea | K02D10.1a 31 |
|
|
|
| K02D10.1b 31 |
|
|
|||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.6771 30 |
|
OneToMany | |
| Bread mold (Neurospora crassa) |
Ascomycetes | NCU08092 29 |
|
- Species where no ortholog for NIPSNAP1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for NIPSNAP1 Gene
- ENSEMBL:
- Gene Tree for NIPSNAP1 (if available)
- TreeFam:
- Gene Tree for NIPSNAP1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for NIPSNAP1: view image
- Alliance of Genome Resources:
- Additional Orthologs for NIPSNAP1
Paralogs for NIPSNAP1 Gene
Variants for NIPSNAP1 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for NIPSNAP1 Gene
| SNP ID | Clinical significance and condition | Chr 22 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1058646 | -- |
p.Glu245Lys |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2665021 | CNV | deletion | 23128226 |
| esv3647539 | CNV | gain | 21293372 |
| esv3647540 | CNV | loss | 21293372 |
| esv3647541 | CNV | loss | 21293372 |
| nsv1110864 | OTHER | inversion | 24896259 |
| nsv521852 | CNV | loss | 19592680 |
| nsv834172 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
25.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.54;
11.70% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for NIPSNAP1 Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NIPSNAP1 Gene
Disorders for NIPSNAP1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| phenylketonuria |
|
|
| fibrous meningioma |
|
|
Search NIPSNAP1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for NIPSNAP1
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for NIPSNAP1 Gene
Publications for NIPSNAP1 Gene
- Characterization of the human NIPSNAP1 gene from 22q12: a member of a novel gene family. (PMID: 9661659) Seroussi E … Dumanski JP (Gene 1998) 2 3 4 22
- Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson SL … O'Brien SJ (PloS one 2010) 3 40
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding. (PMID: 32457219) Tran DT … Itkin-Ansari P (Diabetes 2020) 3
- A High-Density Human Mitochondrial Proximity Interaction Network. (PMID: 32877691) Antonicka H … Shoubridge EA (Cell metabolism 2020) 3
ExternalLinks
Products for NIPSNAP1 Gene
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for NIPSNAP1
- Search Origene for MassSpec and Protein Over-expression Lysates for NIPSNAP1
- Origene Custom Protein Services for NIPSNAP1
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- OriGene qPCR primer pairs for NIPSNAP1
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- High-throughput Antibody Production Service
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- Epitope Tag Antibodies & Reporter Protein Antibodies
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- Novus Biologicals proteins for NIPSNAP1
- Browse Antibodies
- Browse Peptides and Proteins
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- Abcam antibodies for NIPSNAP1
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- Browse Primary Antibodies
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- Browse Monoclonal Antibodies
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- VectorBuilder Custom and pre-made DNA vectors for NIPSNAP1 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for NIPSNAP1 (ie. lentivirus, AAV, adenovirus)
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- VectorBuilder Stable cell line generation for NIPSNAP1
- antibodies-online: Show 3 available NIPSNAP1 Antibodies ranked by validation data
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- antibodies-online: Search results for available NIPSNAP1 related products ranked by validation data
- antibodies-online: Show 6 available NIPSNAP1 Proteins ranked by validation data
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- Quality Products:
- Santa Cruz Biotechnology (SCBT) Antibodies for NIPSNAP1
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- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for NIPSNAP1
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- Boster Bio Antibodies for NIPSNAP1
- Browse Boster Bio ELISA Kits
Sources for NIPSNAP1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Apr-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) ASD
- (27) SAGE
- (28) SOURCE
- (29) HomoloGene
- (30) PanEnsembl
- (31) euGenes
- (32) SGD
- (33) FlyBase
- (34) WormBase
- (35) Pseudogene
- (36) DGV
- (37) dbSNP
- (38) GenAtlas
- (39) HGMD
- (40) GAD
- (41) BGMUT
- (42) HuGE
- (43) Atlas
- (44) GenBank
- (45) HORDE
- (46) HUGE
- (47) IMGT
- (48) Leiden
- (49) miRBase
- (50) DME
- (51) OriGene
- (52) PubMed
- (53) R&D Systems
- (54) Tocris
- (55) Abcam
- (56) Novus Biologicals
- (57) ProSpec
- (58) Sino Biological
- (59) GenScript
- (60) Qiagen
- (61) OCA
- (62) Proteopedia
- (63) MOPED
- (64) neXtProt
- (65) Reactome
- (66) GeneGo (Thomson Reuters)
- (67) DISEASES
- (68) SIMAP
- (69) GenomeRNAi
- (70) LifeMap
- (71) miRTarBase
- (72) MalaCards
- (73) Invitrogen
- (74) BitterDB
- (75) ESI-BIO
- (76) RefSeq
- (77) BioSystems
- (78) MaxQB
- (79) IUPHAR
- (80) BioGPS
- (81) Illumina
- (82) COMPARTMENTS
- (83) HOMER
- (84) PaxDb
- (85) ApexBio
- (86) Addgene
- (87) antibodies-online
- (88) CYP
- (89) NONCODE
- (90) TreeFam
- (91) PathCards
- (92) GeneReviews
- (93) GeneTex
- (94) Taconic Biosciences
- (95) GTEx
- (96) ProteomicsDB
- (97) SCBT
- (98) DGIdb
- (99) ClinicalTrials
- (100) RVIS
- (101) SIGNOR
- (102) diseasecard
- (103) NIH Rare Diseases
- (104) Orphanet
- (105) UMLS
- (106) GTR
- (107) Disease Ontology
- (108) MedlinePlus Genetics
- (109) MeSH
- (110) MedlinePlus
- (111) CDC
- (112) NINDS
- (113) NCBI Bookshelf
- (114) ClinVar
- (115) Gene Damage Index
- (116) HPO
- (117) UDN
- (118) VISTA
- (119) FANTOM5
- (120) ENCODE
- (121) ProSci
- (122) Horizon
- (123) The Signaling Pathways Project (SPP)
- (124) IID
- (125) VectorBuilder
- (126) SNPedia
- (127) BRCA Exchange
- (128) CIViC
- (129) ProteoGenix
- (130) dbSUPER
- (131) TISSUES
- (132) Gene ORGANizer
- (133) abm
- (134) Human Protein Atlas
- (135) GWAS Catalog
- (136) Monarch Initiative
- (137) DataMed
- (138) HumanCyc
- (139) UCNEbase
- (140) EPDnew
- (141) Applied Biosystems
- (142) GlyConnect
- (143) Aminode
- (144) GeneCopoeia
- (145) GPS-Prot
- (146) RNAcentral
- (147) LncRNADisease
- (148) LOVD
- (149) miR2Disease
- (150) DiseaseEnhancer
- (151) Boster Bio
- (152) Biorbyt
- (153) Biocompare
- (154) Mastermind
- (155) CTD^2 Dashboard
- (156) CraniofacialAtlas
- (157) GeneImprint
- (158) Synthego
- (159) ENA
- (160) GtRNAdb
- (161) LncBase
- (162) LncBook
- (163) LNCipedia
- (164) Modomics
- (165) PDBe
- (166) Rfam
- (167) SILVA
- (168) snOPY
- (169) SRPDB
- (170) GENCODE
- (171) TarBase
- (172) Open Targets Platform
- (173) 5SRRNADB
- (174) snoDB
- (175) MirGeneDB
- (176) Alliance of Genome Resources