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The ninjurin protein is upregulated after nerve injury both in dorsal root ganglion neurons and in Schwann cells (Araki and Milbrandt, 1996 [PubMed 8780658]). It demonstrates properties of a homophilic adhesion molecule and promotes neurite outgrowth from primary cultured dorsal root ganglion neurons.[supplied by OMIM, Aug 2009] See more...
Aliases for NINJ1 Gene
Aliases for NINJ1 Gene
External Ids for NINJ1 Gene
- HGNC: 7824
- NCBI Entrez Gene: 4814
- Ensembl: ENSG00000131669
- OMIM®: 602062
- UniProtKB/Swiss-Prot: Q92982
Previous GeneCards Identifiers for NINJ1 Gene
- GC09M086710
- GC09M087611
- GC09M089182
- GC09M091225
- GC09M092963
- GC09M094923
- GC09M095883
- GC09M065560
Summaries for NINJ1 Gene
-
The ninjurin protein is upregulated after nerve injury both in dorsal root ganglion neurons and in Schwann cells (Araki and Milbrandt, 1996 [PubMed 8780658]). It demonstrates properties of a homophilic adhesion molecule and promotes neurite outgrowth from primary cultured dorsal root ganglion neurons.[supplied by OMIM, Aug 2009]
GeneCards Summary for NINJ1 Gene
NINJ1 (Ninjurin 1) is a Protein Coding gene. Diseases associated with NINJ1 include Hereditary Sensory Neuropathy and Waardenburg Syndrome, Type 4C. An important paralog of this gene is NINJ2.
UniProtKB/Swiss-Prot Summary for NINJ1 Gene
-
Homophilic cell adhesion molecule that promotes axonal growth. May play a role in nerve regeneration and in the formation and function of other tissues. Cell adhesion requires divalent cations.
Additional gene information for NINJ1 Gene
- HGNC (7824)
- NCBI Entrez Gene (4814)
- Ensembl (ENSG00000131669)
- OMIM® (602062)
- UniProtKB/Swiss-Prot (Q92982)
- Open Targets Platform(ENSG00000131669)
- Monarch Initiative
- Search for NINJ1 at DataMed
- Search for NINJ1 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for NINJ1 Gene
Genomics for NINJ1 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for NINJ1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around NINJ1 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for NINJ1
- Top Transcription factor binding sites by QIAGEN in the NINJ1 gene promoter:
-
- AML1a
- ATF6
- Bach2
- E47
- FOXO4
- GATA-3
- NF-kappaB1
- p53
- Pax-5
Genomic Locations for NINJ1 Gene
Latest Assembly
- chr9:93,121,496-93,134,304
- (GRCh38/hg38)
- Size:
- 12,809 bases
- Orientation:
- Minus strand
Previous Assembly
- chr9:95,883,778-95,896,533
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 12,756 bases
- Orientation:
- Minus strand
- chr9:95,883,771-95,896,570
- (GRCh37/hg19 by Ensembl)
- Size:
- 12,800 bases
- Orientation:
- Minus strand
Genomic View for NINJ1 Gene
Genes around NINJ1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 9q22.31 by HGNC
- 9q22.31 by Entrez Gene
- 9q22.31 by Ensembl
NINJ1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for NINJ1 Gene
Proteins for NINJ1 Gene
-
Protein details for NINJ1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q92982-NINJ1_HUMAN
- Recommended name:
- Ninjurin-1
- Protein Accession:
- Q92982
- Q6GU89
- Q8WUV5
- Q9BT07
Protein attributes for NINJ1 Gene
- Size:
- 152 amino acids
- Molecular mass:
- 16345 Da
- Quaternary structure:
- No Data Available
Protein Expression for NINJ1 Gene
Post-translational modifications for NINJ1 Gene
Other Protein References for NINJ1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- LifeSpan BioSciences NINJ1 / Ninjurin Antibody (LS-B12103) and NINJ1 / Ninjurin Antibody (LS-B12620)
- Novus Biologicals Antibodies for NINJ1
-
Abcam antibodies for NINJ1
- Invitrogen Antibodies for NINJ1 (AFLGC-Ninj1)
-
Boster Bio Antibodies for NINJ1
-
Custom Antibody ServicesProSci Antibodies for NINJ1
-
Santa Cruz Biotechnology (SCBT) Antibodies for NINJ1
Protein products for research
-
OriGene Purified Proteins for NINJ1
- Search Origene for MassSpec and Protein Over-expression Lysates for NINJ1
- Origene Custom Protein Services for NINJ1
- Sino Biological Recombinant Proteins for NINJ1
- Sino Biological Cell Lysates for NINJ1
- antibodies-online: Show 6 available NINJ1 Proteins ranked by validation data
- Compare Top NINJ1 Proteins
-
Quality Products:
-
Abcam proteins for NINJ1
Assay products for research
- RayBiotech Custom Human Ninjurin-1 ELISA
- antibodies-online: Show 15 available NINJ1 Elisa Kits ranked by validation data
- Compare Top NINJ1 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for NINJ1 Gene
Domains & Families for NINJ1 Gene
Gene Families for NINJ1 Gene
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
Suggested Antigen Peptide Sequences for NINJ1 Gene
- GenScript: Design optimal peptide antigens:
-
- Nerve injury-induced protein 1 (NINJ1_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q92982- Family:
-
- Belongs to the ninjurin family.
Function for NINJ1 Gene
Molecular function for NINJ1 Gene
- UniProtKB/Swiss-Prot Function:
- Homophilic cell adhesion molecule that promotes axonal growth. May play a role in nerve regeneration and in the formation and function of other tissues. Cell adhesion requires divalent cations.
- UniProtKB/Swiss-Prot Induction:
- By nerve injury both in dorsal root ganglion neurons and in Schwann cells.
- GENATLAS Biochemistry:
- mouse ninjurin homolog,nerve injury induced protein,cell surface molecule,promoting axonal growth
Phenotypes From GWAS Catalog for NINJ1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 25416956 |
Phenotypes for NINJ1 Gene
- MGI mutant phenotypes for NINJ1:
- inferred from 3 alleles
- GenomeRNAi human phenotypes for NINJ1:
-
- Increased vaccinia virus (VACV) infection
- no effect
- Decreased viability
- Decreased NF-kappaB reporter expression
- Increased shRNA abundance (Z-score > 2)
- Decreased shRNA abundance (Z-score < -2)
- Negative genetic interaction between PTTG1-/- and PTTG1+/+
- Synthetic lethal with vaccinia virus (VACV) infection
- Increased caspase activity
Animal Models for NINJ1 Gene
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for NINJ1 - Starting at $85 >
- * NINJ1 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for NINJ1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for NINJ1
-
Santa Cruz Biotechnology (SCBT) CRISPR for NINJ1
miRNA for NINJ1 Gene
- miRTarBase miRNAs that target NINJ1
-
- hsa-miR-107 (MIRT026972)
- hsa-miR-3658 (MIRT441755)
- hsa-miR-3653-3p (MIRT441756)
- hsa-miR-6499-3p (MIRT441757)
- hsa-miR-3613-3p (MIRT441758)
- hsa-miR-5700 (MIRT441759)
- hsa-miR-6507-5p (MIRT441760)
- hsa-miR-6807-5p (MIRT515931)
- hsa-miR-7151-3p (MIRT515932)
- hsa-miR-5095 (MIRT515933)
- hsa-miR-550a-5p (MIRT515934)
- hsa-miR-550a-3-5p (MIRT515935)
- hsa-miR-1271-3p (MIRT515936)
- hsa-miR-6759-3p (MIRT515937)
- hsa-miR-6504-3p (MIRT515938)
- hsa-miR-4438 (MIRT515940)
- hsa-miR-335-3p (MIRT639333)
- hsa-miR-452-3p (MIRT639334)
- hsa-miR-627-3p (MIRT639335)
- hsa-miR-4704-3p (MIRT639336)
- hsa-miR-587 (MIRT645423)
- hsa-miR-3671 (MIRT645424)
- hsa-miR-6884-3p (MIRT645425)
- hsa-miR-5094 (MIRT645426)
- hsa-miR-3529-3p (MIRT645427)
- hsa-miR-1298-5p (MIRT709778)
- hsa-miR-7154-5p (MIRT709779)
- hsa-miR-433-3p (MIRT709780)
- hsa-miR-6853-3p (MIRT709781)
- hsa-miR-5701 (MIRT709782)
- hsa-miR-4417 (MIRT709783)
- hsa-miR-1206 (MIRT709784)
- hsa-miR-27a-5p (MIRT709786)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for NINJ1
- Browse OriGene Inhibitory RNA Products For NINJ1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NINJ1
Clone products for research
- Applied Biological Materials (abm): Clones for NINJ1 - Starting at $45 >
- * NINJ1 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for NINJ1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for NINJ1
Cell Lines for research
-
Horizon Cell Lines for NINJ1
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for NINJ1 Gene
Localization for NINJ1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for NINJ1 Gene
- Membrane. Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 3 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| nucleus | 1 |
| cytosol | 1 |
| peroxisome | 0 |
| endoplasmic reticulum | 0 |
| golgi apparatus | 0 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for NINJ1 Gene
Pathways & Interactions for NINJ1 Gene
Interacting Proteins for NINJ1 Gene
Selected Interacting proteins:
Q92982-NINJ1_HUMAN
ENSP00000364595
for NINJ1 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for NINJ1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007155 | cell adhesion | TAS,IBA | 21873635 |
| GO:0007399 | nervous system development | TAS | 9261151 |
| GO:0042246 | tissue regeneration | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for NINJ1 Gene
Transcripts for NINJ1 Gene
mRNA/cDNA for NINJ1 Gene
- 1 REFSEQ mRNAs :
- 8 NCBI additional mRNA sequence :
- 5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000375446 1237 nts (view in UCSC)
- ENST00000461162 861 nts (view in UCSC)
- ENST00000470314 834 nts (view in UCSC)
- ENST00000489274 2026 nts (view in UCSC)
- ENST00000490564 488 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for NINJ1 - Starting at $85 >
- * NINJ1 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for NINJ1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for NINJ1
-
Santa Cruz Biotechnology (SCBT) CRISPR for NINJ1
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for NINJ1
- Browse OriGene Inhibitory RNA Products For NINJ1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NINJ1
Clone products for research
- Applied Biological Materials (abm): Clones for NINJ1 - Starting at $45 >
- * NINJ1 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for NINJ1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for NINJ1
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | ^ | 5a | · | 5b | · | 5c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||||
| SP3: | - | - | - | - | |||||||||||||||||||
| SP4: | |||||||||||||||||||||||
| SP5: | - |
Relevant External Links for NINJ1 Gene
- GeneLoc Exon Structure for
- NINJ1
Expression for NINJ1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Bone (Muscoskeletal System)
-
Blood (Hematopoietic System)
- Granulocytes Peripheral Blood
-
Placenta (Extraembryonic Tissues)
-
Spleen (Hematopoietic System)
-
Thyroid (Endocrine System)
-
Kidney (Urinary System)
-
Adrenal Gland (Endocrine System)
mRNA differential expression in normal tissues according to GTEx for NINJ1 Gene
This gene is overexpressed in Whole Blood (x11.6).
This gene is overexpressed in Frontal cortex (8.3), Spinal cord (6.8), Testis (6.6), Monocytes (6.5), and Ovary (6.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for NINJ1 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for NINJ1
SOURCE GeneReport for Unigene cluster for NINJ1 Gene:
Hs.494457mRNA Expression by UniProt/SwissProt for NINJ1 Gene:
Q92982-NINJ1_HUMAN
Tissue specificity:
Widely expressed in both adult and embryonic tissues, primarily those of epithelial origin.
Evidence on tissue expression from TISSUES for NINJ1 Gene
- Skin(4.5)
- Lung(4.5)
- Nervous system(2.5)
- Bone marrow(2.5)
- Heart(2.4)
- Spleen(2.2)
- Liver(2.1)
- Intestine(2.1)
- Lymph node(2)
- Muscle(2)
- Adrenal gland(2)
Primer products for research
-
OriGene qPCR primer pairs for NINJ1
-
OriGene qPCR primer pairs and template standards for NINJ1
Gene Expression Assays for research
No data available for Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for NINJ1 Gene
Orthologs for NINJ1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | NINJ1 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | NINJ1 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Ninj1 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Ninj1 30 |
|
||
| Cow (Bos Taurus) |
Mammalia | NINJ1 30 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | NINJ1 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | NINJ1 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | NINJ1 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | NINJ1 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | ninj1 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | LOC100150223 30 |
|
||
| NINJ1 31 |
|
OneToOne | |||
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG14394 31 |
|
ManyToMany | |
| CG11637 31 |
|
ManyToMany | |||
| NijA 31 |
|
ManyToMany |
- Species where no ortholog for NINJ1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for NINJ1 Gene
- ENSEMBL:
- Gene Tree for NINJ1 (if available)
- TreeFam:
- Gene Tree for NINJ1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for NINJ1: view image
Paralogs for NINJ1 Gene
Variants for NINJ1 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for NINJ1 Gene
| SNP ID | Clinical significance and condition | Chr 09 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs2275848 | - |
p.Ala110Asp |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1128505 | CNV | deletion | 24896259 |
| nsv1134927 | CNV | tandem duplication | 24896259 |
| nsv1161884 | CNV | deletion | 26073780 |
| nsv526296 | CNV | loss | 19592680 |
| nsv614879 | CNV | loss | 21841781 |
| nsv824982 | CNV | gain | 20364138 |
Residual Variation Intolerance Score:
67.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.06;
21.60% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for NINJ1 Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NINJ1 Gene
Disorders for NINJ1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| hereditary sensory neuropathy |
|
|
| waardenburg syndrome, type 4c |
|
|
Search NINJ1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for NINJ1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for NINJ1 Gene
Publications for NINJ1 Gene
- Ninjurin, a novel adhesion molecule, is induced by nerve injury and promotes axonal growth. (PMID: 8780658) Araki T … Milbrandt J (Neuron 1996) 2 3 4 23
- The human homologue of the ninjurin gene maps to the candidate region of hereditary sensory neuropathy type I (HSNI). (PMID: 9465296) Chadwick BP … Frischauf AM (Genomics 1998) 3 4 23
- Mechanism of homophilic binding mediated by ninjurin, a novel widely expressed adhesion molecule. (PMID: 9261151) Araki T … Milbrandt J (The Journal of biological chemistry 1997) 3 4 23
- Genetic susceptibility to distinct bladder cancer subphenotypes. (PMID: 19692168) Guey LT … EPICURO/Spanish Bladder Cancer Study investigators (European urology 2010) 3 41
- Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China. (PMID: 19170196) Shen M … Lan Q (Environmental and molecular mutagenesis 2009) 3 41
ExternalLinks
Products for NINJ1 Gene
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- antibodies-online: Show 5 available NINJ1 Antibodies ranked by validation data
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- antibodies-online: Show 6 available NINJ1 Proteins ranked by validation data
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- Quality Products:
- Santa Cruz Biotechnology (SCBT) Antibodies for NINJ1
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- Search for NINJ1 Proteins at ProSci
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- Boster Bio Antibodies for NINJ1
- Browse Boster Bio ELISA Kits
Sources for NINJ1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
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- (111) MeSH
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- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB