External Ids for NID2 Gene
Previous GeneCards Identifiers for NID2 Gene
This gene encodes a member of the nidogen family of basement membrane proteins. This protein is a cell-adhesion protein that binds collagens I and IV and laminin and may be involved in maintaining the structure of the basement membrane.[provided by RefSeq, Jun 2010]
GeneCards Summary for NID2 Gene
NID2 (Nidogen 2) is a Protein Coding gene. Diseases associated with NID2 include Clivus Chordoma. Among its related pathways are Degradation of the extracellular matrix and MET promotes cell motility. Gene Ontology (GO) annotations related to this gene include calcium ion binding and collagen binding. An important paralog of this gene is NID1.
UniProtKB/Swiss-Prot Summary for NID2 Gene
Cell adhesion glycoprotein which is widely distributed in basement membranes. Binds to collagens I and IV, to perlecan and to laminin 1. Does not bind fibulins. It probably has a role in cell-extracellular matrix interactions.