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NIBAN2 (Niban Apoptosis Regulator 2) is a Protein Coding gene. Diseases associated with NIBAN2 include Melanoma. Among its related pathways are MAP Kinase Signaling. An important paralog of this gene is NIBAN1.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003713 | transcription coactivator activity | IDA | 17569660 |
GO:0005515 | protein binding | IPI | 19615732 |
GO:0045296 | cadherin binding | HDA | 25468996 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | NOT nucleus | IDA | 21148485 |
GO:0005654 | nucleoplasm | IDA | -- |
GO:0005737 | cytoplasm | IEA,IDA | 14602737 |
GO:0005829 | cytosol | IEA,IDA | 21148485 |
GO:0005886 | plasma membrane | IDA | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | MAP Kinase Signaling |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0007411 | axon guidance | ISS | -- |
GO:0008285 | negative regulation of cell proliferation | IDA | 14602737 |
GO:0016525 | negative regulation of angiogenesis | ISS | -- |
GO:0030154 | cell differentiation | ISS | -- |
GO:0030948 | negative regulation of vascular endothelial growth factor receptor signaling pathway | ISS | -- |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | FAM129B 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | FAM129B 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | FAM129B 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Fam129b 30 31 |
|
OneToOne | |
Niban2 17 |
|
||||
Rat (Rattus norvegicus) |
Mammalia | Fam129b 30 |
|
||
Oppossum (Monodelphis domestica) |
Mammalia | FAM129B 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | FAM129B 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | FAM129B 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | FAM129B 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | fam129b 30 |
|
||
Str.8124 30 |
|
||||
Zebrafish (Danio rerio) |
Actinopterygii | fam129bb 30 31 |
|
OneToMany | |
FAM129B (3 of 3) 31 |
|
OneToMany | |||
fam129ba 31 |
|
OneToMany |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv2739053 | CNV | deletion | 23290073 |
nsv1133741 | CNV | deletion | 24896259 |
nsv1145265 | CNV | deletion | 24896259 |
nsv466569 | CNV | loss | 19166990 |
nsv466570 | CNV | loss | 19166990 |
nsv615368 | CNV | loss | 21841781 |
Disorder | Aliases | PubMed IDs |
---|---|---|
melanoma |
|
|