Aliases for NGF-AS1 Gene

Data sources for NGF-AS1 Gene:

Subcategory (RNA class) for NGF-AS1 Gene

lncRNA

Aliases for NGF-AS1 Gene

External Ids for NGF-AS1 Gene

Previous GeneCards Identifiers for NGF-AS1 Gene

  • GC01P115287

Summaries for NGF-AS1 Gene

GeneCards Summary for NGF-AS1 Gene

NGF-AS1 (NGF Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with NGF-AS1 include Neuropathy, Hereditary Sensory And Autonomic, Type V and Charcot-Marie-Tooth Disease.

Additional gene information for NGF-AS1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for NGF-AS1 Gene

Genomics for NGF-AS1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for NGF-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J115282 Promoter/Enhancer 1.3 EPDnew Ensembl ENCODE dbSUPER 256.6 +54.5 54458 2.8 RXRA JUND RAD21 SP1 DACH1 NR2F2 NGF-AS1 ENSG00000285698 piR-45035-012 NGF TSPAN2
GH01J115227 Enhancer 0.7 Ensembl ENCODE dbSUPER 250.7 -0.9 -901 2.4 CEBPB FOS NGF-AS1 NGF HSALNG0006266 lnc-TSHB-2 TSPAN2
GH01J115230 Enhancer 0.2 Ensembl 250.7 +1.2 1221 1 NGF-AS1 NGF HSALNG0006268 lnc-TSHB-2 TSPAN2
GH01J115188 Enhancer 1.3 FANTOM5 Ensembl ENCODE dbSUPER 10.6 -39.0 -38980 3.4 CEBPB MAX EP300 RFX5 SMC3 STAT3 BCL6 TBP RAD21 JUND NGF NGF-AS1 SIKE1 lnc-TSHB-2 HSALNG0006266 TSPAN2
GH01J115425 Enhancer 1.1 FANTOM5 Ensembl ENCODE 10.5 +199.9 199921 7.6 CEBPA BRCA1 CEBPB CUX1 MAX MAFF EP300 CTBP1 RFX5 STAT3 NGF SIKE1 TRIM33 NGF-AS1 ATP1A1-AS1 HSALNG0006273 RF00994-048 VANGL1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around NGF-AS1 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for NGF-AS1 Gene

Latest Assembly
chr1:115,229,280-115,373,054
(GRCh38/hg38)
Size:
143,775 bases
Orientation:
Plus strand

Previous Assembly
chr1:115,825,655-115,910,693
(GRCh37/hg19 by Entrez Gene)
Size:
85,039 bases
Orientation:
Plus strand

chr1:115,825,655-115,910,693
(GRCh37/hg19 by Ensembl)
Size:
85,039 bases
Orientation:
Plus strand

Genomic View for NGF-AS1 Gene

Genes around NGF-AS1 on UCSC Golden Path with GeneCards custom track
NGF-AS1 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
NGF-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NGF-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NGF-AS1 Gene

Proteins for NGF-AS1 Gene

Post-translational modifications for NGF-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for NGF-AS1 Gene

Domains & Families for NGF-AS1 Gene

Gene Families for NGF-AS1 Gene

genes like me logo Genes that share domains with NGF-AS1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for NGF-AS1 Gene

Function for NGF-AS1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NGF-AS1 Gene

Localization for NGF-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for NGF-AS1 Gene

Pathways & Interactions for NGF-AS1 Gene

PathCards logo

SuperPathways for NGF-AS1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for NGF-AS1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for NGF-AS1 Gene

Drugs & Compounds for NGF-AS1 Gene

No Compound Related Data Available

Transcripts for NGF-AS1 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for NGF-AS1 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS0000049FC4_9606 lncRNA 2610 3

RefSeq: NR_157569,

Ensembl: ENST00000425449 (view in UCSC) ,

LNCipedia: NGF-AS1:8,

URS00008B27EE_9606 lncRNA 2801 3

LncBook: HSALNT0013112,

LNCipedia: NGF-AS1:9,

NONCODE: NONHSAT005387.2,

URS00009B38BE_9606 lncRNA 2610 2

LncBook: HSALNT0013113,

NONCODE: NONHSAT149634.1,

URS0001BEDC76_9606 lncRNA 7910 1

LncBook: HSALNT0013105,

URS0001BD4097_9606 lncRNA 7646 1

LncBook: HSALNT0013111,

NGF-AS1 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for NGF-AS1 Gene

No ASD Table

Relevant External Links for NGF-AS1 Gene

GeneLoc Exon Structure for
NGF-AS1

No data available for mRNA/cDNA for NGF-AS1 Gene

Expression for NGF-AS1 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NGF-AS1 Gene

Orthologs for NGF-AS1 Gene

Evolution for NGF-AS1 Gene

ENSEMBL:
Gene Tree for NGF-AS1 (if available)
TreeFam:
Gene Tree for NGF-AS1 (if available)

No data available for Orthologs for NGF-AS1 Gene

Paralogs for NGF-AS1 Gene

No data available for Paralogs for NGF-AS1 Gene

Variants for NGF-AS1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for NGF-AS1 Gene

SNP ID Clinical significance and condition Chr 01 pos Variation AA Info Type
834309 Uncertain Significance: Congenital sensory neuropathy with selective loss of small myelinated fibers 115,286,234(+) C/G
NM_002506.3(NGF):c.562G>C (p.Gly188Arg)
MISSENSE
835507 Uncertain Significance: Congenital sensory neuropathy with selective loss of small myelinated fibers 115,286,478(+) C/G
NM_002506.3(NGF):c.318G>C (p.Glu106Asp)
MISSENSE
837334 Uncertain Significance: Congenital sensory neuropathy with selective loss of small myelinated fibers 115,286,164(+) A/G
NM_002506.3(NGF):c.632T>C (p.Leu211Pro)
MISSENSE
841314 Uncertain Significance: Congenital sensory neuropathy with selective loss of small myelinated fibers 115,286,558(+) G/A
NM_002506.3(NGF):c.238C>T (p.Arg80Trp)
MISSENSE
848301 Uncertain Significance: Congenital sensory neuropathy with selective loss of small myelinated fibers 115,286,612(+) G/A
NM_002506.3(NGF):c.184C>T (p.Arg62Cys)
MISSENSE

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for NGF-AS1 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Additional Variant Information for NGF-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
NGF-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for NGF-AS1 Gene

Disorders for NGF-AS1 Gene

MalaCards: The human disease database

(2) MalaCards diseases for NGF-AS1 Gene - From: CVR and GCD

Disorder Aliases PubMed IDs
neuropathy, hereditary sensory and autonomic, type v
  • hsan5
charcot-marie-tooth disease
  • cmt - charcot-marie-tooth disease
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for NGF-AS1

genes like me logo Genes that share disorders with NGF-AS1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for NGF-AS1 Gene

Publications for NGF-AS1 Gene

  1. Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs. (PMID: 29855537) Hirata T … Osuga Y (Scientific reports 2018) 2 3
  2. A novel NGF mutation clarifies the molecular mechanism and extends the phenotypic spectrum of the HSAN5 neuropathy. (PMID: 20978020) Carvalho OP … Woods CG (Journal of medical genetics 2011) 74
  3. A mutation in the nerve growth factor beta gene (NGFB) causes loss of pain perception. (PMID: 14976160) Einarsdottir E … Holmberg M (Human molecular genetics 2004) 74

Products for NGF-AS1 Gene

Sources for NGF-AS1 Gene