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The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of... See more...
Aliases for NFYA Gene
Aliases for NFYA Gene
External Ids for NFYA Gene
- HGNC: 7804
- NCBI Entrez Gene: 4800
- Ensembl: ENSG00000001167
- OMIM®: 189903
- UniProtKB/Swiss-Prot: P23511
Previous GeneCards Identifiers for NFYA Gene
- GC06P041042
- GC06P041087
- GC06P041148
- GC06P041040
- GC06P040758
- GC06P042924
- GC06P043252
- GC06P043410
- GC06P046092
- GC06P041074
- GC06P041309
- GC06P041321
- GC06P041983
- GC06P042629
- GC06P047497
- GC06P049557
Summaries for NFYA Gene
-
The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms. [provided by RefSeq, Jul 2008]
GeneCards Summary for NFYA Gene
NFYA (Nuclear Transcription Factor Y Subunit Alpha) is a Protein Coding gene. Among its related pathways are Unfolded Protein Response (UPR) and Regulation of cholesterol biosynthesis by SREBP (SREBF). Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and transcription regulatory region DNA binding.
UniProtKB/Swiss-Prot Summary for NFYA Gene
-
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors. NF-YA positively regulates the transcription of the core clock component ARNTL/BMAL1.
Additional gene information for NFYA Gene
- HGNC (7804)
- NCBI Entrez Gene (4800)
- Ensembl (ENSG00000001167)
- OMIM® (189903)
- UniProtKB/Swiss-Prot (P23511)
- Open Targets Platform(ENSG00000001167)
- Alliance of Genome Resources
- Search for NFYA at DataMed
- Search for NFYA at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for NFYA Gene
Genomics for NFYA Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for NFYA Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around NFYA on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for NFYA
- Top Transcription factor binding sites by QIAGEN in the NFYA gene promoter:
-
- CUTL1
- GATA-1
- p53
Genomic Locations for NFYA Gene
Latest Assembly
- chr6:41,072,945-41,102,403
- (GRCh38/hg38)
- Size:
- 29,459 bases
- Orientation:
- Plus strand
Previous Assembly
- chr6:41,040,713-41,070,142
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 29,430 bases
- Orientation:
- Plus strand
Genomic View for NFYA Gene
Genes around NFYA on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p21.1 by HGNC
- 6p21.1 by Entrez Gene
- 6p21.1 by Ensembl
NFYA Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for NFYA Gene
Proteins for NFYA Gene
-
Protein details for NFYA Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P23511-NFYA_HUMAN
- Recommended name:
- Nuclear transcription factor Y subunit alpha
- Protein Accession:
- P23511
- Q8IXU0
Protein attributes for NFYA Gene
- Size:
- 347 amino acids
- Molecular mass:
- 36877 Da
- Quaternary structure:
-
- Heterotrimeric transcription factor composed of three components, NF-YA, NF-YB and NF-YC. NF-YB and NF-YC must interact and dimerize for NF-YA association and DNA binding. Interacts with SP1; the interaction is inhibited by glycosylation of SP1. Interacts with ZHX1. Interacts (via N-terminus) with ZHX2 (via homeobox domain). Interacts with ZFX3.
Three dimensional structures from OCA and Proteopedia for NFYA Gene
Protein Expression for NFYA Gene
Post-translational modifications for NFYA Gene
Other Protein References for NFYA Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- LifeSpan BioSciences NFYA Antibody
- G Biosciences Immunotag™ NFYA Antibody
- GeneTex Anti-NFYA antibody
- Novus Biologicals Antibodies for NFYA
-
Abcam antibodies for NFYA
- Invitrogen Antibodies for NFYA (AFLGC-NFYA)
- antibodies-online: Show 42 available NFYA Antibodies ranked by validation data
-
Biorbyt antibodies for NFYA
-
Santa Cruz Biotechnology (SCBT) Antibodies for NFYA
- Sino Biological Antibodies for NFYA
Protein products for research
- Search Origene for MassSpec and Protein Over-expression Lysates for NFYA
- Origene Custom Protein Services for NFYA
-
Abcam proteins for NFYA
Assay products for research
- antibodies-online: Show 3 available NFYA Elisa Kits ranked by validation data
- Compare Top NFYA Elisa Kits
-
Quality Products:
-
Abcam assays for NFYA
No data available for DME Specific Peptides for NFYA Gene
Domains & Families for NFYA Gene
Gene Families for NFYA Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transcription factors
Protein Domains for NFYA Gene
- InterPro:
- Blocks:
-
- CCAAT-binding transcription factor, subunit B
Suggested Antigen Peptide Sequences for NFYA Gene
- GenScript: Design optimal peptide antigens:
-
- Nuclear transcription factor Y subunit A (NFYA_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P23511- Family:
-
- Belongs to the NFYA/HAP2 subunit family.
Function for NFYA Gene
Molecular function for NFYA Gene
- UniProtKB/Swiss-Prot Function:
- Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors. NF-YA positively regulates the transcription of the core clock component ARNTL/BMAL1.
- GENATLAS Biochemistry:
- nuclear transcription factor NF-Y,A subunit,binding the CCAAT and the inverted CCAT box,Y box (ATGG) motifs in a variety of promoters,interacting with P/CAF
Phenotypes From GWAS Catalog for NFYA Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000976 | contributes_to transcription regulatory region sequence-specific DNA binding | IDA | 11256944 |
| GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding | ISS | -- |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | ISA | -- |
| GO:0003677 | DNA binding | IDA | 15243141 |
| GO:0003700 | DNA-binding transcription factor activity | TAS | 1774067 |
Phenotypes for NFYA Gene
- MGI mutant phenotypes for NFYA:
- inferred from 3 alleles
- GenomeRNAi human phenotypes for NFYA:
Animal Models for NFYA Gene
- MGI Knock Outs for NFYA:
-
- Nfya Nfya<tm1.1Mait>
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for NFYA - Starting at $85 >
- * NFYA CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for NFYA
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for NFYA
-
Santa Cruz Biotechnology (SCBT) CRISPR for NFYA
miRNA for NFYA Gene
- miRTarBase miRNAs that target NFYA
-
- mmu-miR-301b-3p (MIRT007988)
- mmu-miR-19b-3p (MIRT012431)
- hsa-miR-140-3p (MIRT021682)
- hsa-miR-7-5p (MIRT025877)
- hsa-miR-192-5p (MIRT026722)
- hsa-miR-221-3p (MIRT046947)
- hsa-miR-203a-3p (MIRT053441)
- hsa-miR-4668-5p (MIRT566629)
- hsa-miR-548aw (MIRT566630)
- hsa-miR-1468-3p (MIRT566631)
- hsa-miR-548x-5p (MIRT566632)
- hsa-miR-548g-5p (MIRT566633)
- hsa-miR-548f-5p (MIRT566634)
- hsa-miR-548aj-5p (MIRT566635)
- hsa-miR-3613-3p (MIRT566636)
- hsa-miR-6835-3p (MIRT566637)
- hsa-miR-4282 (MIRT566638)
- hsa-miR-548e-5p (MIRT566639)
- hsa-miR-4713-5p (MIRT626150)
- hsa-miR-6845-3p (MIRT626151)
- hsa-miR-2116-3p (MIRT626152)
- hsa-miR-532-3p (MIRT626153)
- hsa-miR-150-5p (MIRT626154)
- hsa-miR-645 (MIRT626155)
- hsa-miR-361-3p (MIRT626156)
- hsa-miR-4286 (MIRT626157)
- hsa-miR-4301 (MIRT626158)
- hsa-miR-6777-3p (MIRT626159)
- hsa-miR-4478 (MIRT626160)
- hsa-miR-4419b (MIRT626161)
- hsa-miR-3929 (MIRT626162)
- hsa-miR-552-5p (MIRT701436)
- hsa-miR-1238-3p (MIRT701437)
- hsa-miR-6839-3p (MIRT701438)
- hsa-miR-4507 (MIRT701439)
- hsa-miR-3940-5p (MIRT701440)
- hsa-miR-502-5p (MIRT701441)
- hsa-miR-4326 (MIRT701442)
- hsa-miR-629-5p (MIRT701443)
Transcription Factor Targets for NFYA Gene
Targeted motifs for NFYA Gene
HOMER Transcription Factor Regulatory Elements motif NFYA
- Consensus sequence: AGCCAATCGG Submotif: canonical Cell Type: NA
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for NFYA
- Browse OriGene Inhibitory RNA Products For NFYA
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NFYA
Clone products for research
- Applied Biological Materials (abm): Clones for NFYA - Starting at $45 >
- * NFYA as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
-
- MG204581
- MG223083
- MR204581
- MR204581L3
- MR204581L4
- MR223083
- MR223083L3
- MR223083L4
- RC205981
- RC205981L3
- RC205981L4
- RC213263
- RC213263L1
- RC213263L2
- RC213263L3
- RC213263L4
- RG205981
- RG213263
- RR211726
- RR211726L3
- RR211726L4
- MR204581L3V
- MR204581L4V
- MR223083L3V
- MR223083L4V
- RC205981L3V
- RC205981L4V
- RC213263L1V
- RC213263L2V
- RC213263L3V
- RC213263L4V
- RR211726L3V
- RR211726L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for NFYA
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for NFYA
No data available for Enzyme Numbers (IUBMB) and Human Phenotype Ontology for NFYA Gene
Localization for NFYA Gene
Subcellular locations from UniProtKB/Swiss-Prot for NFYA Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| cytosol | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
- Nucleoplasm (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000785 | chromatin | ISA | -- |
| GO:0005634 | nucleus | TAS,IDA | 15243141 |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0016602 | CCAAT-binding factor complex | IBA,IDA | 15243141 |
| GO:0032993 | protein-DNA complex | IDA | 11256944 |
Pathways & Interactions for NFYA Gene
Pathways by source for NFYA Gene
5 BioSystems pathways for NFYA Gene
3 KEGG pathways for NFYA Gene
1 GeneGo (Thomson Reuters) pathway for NFYA Gene
- Transcription Ligand-dependent activation of the ESR1/SP pathway
Interacting Proteins for NFYA Gene
Selected Interacting proteins:
P23511-NFYA_HUMAN
ENSP00000345702
for NFYA Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for NFYA
SIGNOR curated interactions for NFYA Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006355 | regulation of transcription, DNA-templated | IDA | 15243141 |
| GO:0006357 | regulation of transcription by RNA polymerase II | IBA | 21873635 |
| GO:0006366 | transcription by RNA polymerase II | TAS | 2000400 |
| GO:0045540 | regulation of cholesterol biosynthetic process | TAS | -- |
| GO:0045893 | positive regulation of transcription, DNA-templated | ISS | -- |
Transcripts for NFYA Gene
mRNA/cDNA for NFYA Gene
- 2 REFSEQ mRNAs :
- 12 NCBI additional mRNA sequence :
- 2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000341376 3811 nts (view in UCSC)
- ENST00000353205 1660 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for NFYA - Starting at $85 >
- * NFYA CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for NFYA
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for NFYA
-
Santa Cruz Biotechnology (SCBT) CRISPR for NFYA
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for NFYA
- Browse OriGene Inhibitory RNA Products For NFYA
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NFYA
Clone products for research
- Applied Biological Materials (abm): Clones for NFYA - Starting at $45 >
- * NFYA as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
-
- MG204581
- MG223083
- MR204581
- MR204581L3
- MR204581L4
- MR223083
- MR223083L3
- MR223083L4
- RC205981
- RC205981L3
- RC205981L4
- RC213263
- RC213263L1
- RC213263L2
- RC213263L3
- RC213263L4
- RG205981
- RG213263
- RR211726
- RR211726L3
- RR211726L4
- MR204581L3V
- MR204581L4V
- MR223083L3V
- MR223083L4V
- RC205981L3V
- RC205981L4V
- RC213263L1V
- RC213263L2V
- RC213263L3V
- RC213263L4V
- RR211726L3V
- RR211726L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for NFYA
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for NFYA
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | · | 11c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||||||||||
| SP4: | - | ||||||||||||||||||||||||||||||
| SP5: | - | - | - | - |
Relevant External Links for NFYA Gene
- GeneLoc Exon Structure for
- NFYA
Expression for NFYA Gene
This gene is overexpressed in Pancreas (15.2), CD8 Tcells (8.2), Blymphocyte (7.7), Peripheral blood mononuclear cells (7.4), and Retina (6.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for NFYA Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for NFYA
SOURCE GeneReport for Unigene cluster for NFYA Gene:
Hs.10441Evidence on tissue expression from TISSUES for NFYA Gene
- Liver(4.5)
- Nervous system(3.4)
- Skin(2.2)
- Intestine(2.2)
- Bone marrow(2)
- Blood(2)
Primer products for research
-
OriGene qPCR primer pairs for NFYA
-
OriGene qPCR primer pairs and template standards for NFYA
Gene Expression Assays for research
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for NFYA Gene
Orthologs for NFYA Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | NFYA 29 30 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | NFYA 30 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | NFYA 29 30 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | NFYA 30 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | NFYA 29 30 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Nfya 29 16 30 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Nfya 29 |
|
||
| Chicken (Gallus gallus) |
Aves | NFYA 29 30 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | NFYA 30 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | nfya 29 |
|
||
| MGC76011 29 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.418 29 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | nfya 29 30 |
|
OneToMany | |
| nfyal 29 30 |
|
OneToMany | |||
| Fruit Fly (Drosophila melanogaster) |
Insecta | Nf-YA 30 |
|
OneToOne | |
| Worm (Caenorhabditis elegans) |
Secernentea | nfya-2 30 |
|
OneToMany | |
| nfya-1 30 |
|
OneToMany | |||
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | HAP2 30 32 |
|
OneToOne | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 30 |
|
OneToOne |
- Species where no ortholog for NFYA was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for NFYA Gene
- ENSEMBL:
- Gene Tree for NFYA (if available)
- TreeFam:
- Gene Tree for NFYA (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for NFYA: view image
- Alliance of Genome Resources:
- Additional Orthologs for NFYA
Paralogs for NFYA Gene
No data available for Paralogs for NFYA Gene
Variants for NFYA Gene
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1117437 | CNV | tandem duplication | 24896259 |
| nsv602970 | CNV | gain | 21841781 |
Residual Variation Intolerance Score:
23.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.65;
13.92% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for NFYA Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for NFYA Gene
Disorders for NFYA Gene
Additional Disease Information for NFYA
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No disorders were found for NFYA Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NFYA Gene
Publications for NFYA Gene
- O-GlcNAcylation of Sp1 interrupts Sp1 interaction with NF-Y. (PMID: 19302979) Lim K … Chang HI (Biochemical and biophysical research communications 2009) 3 4 22
- Analysis of zinc-fingers and homeoboxes (ZHX)-1-interacting proteins: molecular cloning and characterization of a member of the ZHX family, ZHX3. (PMID: 12659632) Yamada K … Miyamoto K (The Biochemical journal 2003) 3 4 22
- Sequence-specific transcription factor NF-Y displays histone-like DNA binding and H2B-like ubiquitination. (PMID: 23332751) Nardini M … Mantovani R (Cell 2013) 3 4
- Gain of function of mutant p53: the mutant p53/NF-Y protein complex reveals an aberrant transcriptional mechanism of cell cycle regulation. (PMID: 16959611) Di Agostino S … Piaggio G (Cancer cell 2006) 3 22
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
ExternalLinks
Products for NFYA Gene
- Custom Antibody Services
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- Search Origene for MassSpec and Protein Over-expression Lysates for NFYA
- Origene Custom Protein Services for NFYA
- Origene shrna, sirna, and RNAi products in human, mouse, rat for NFYA
- Browse OriGene Inhibitory RNA Products For NFYA
- OriGene qPCR primer pairs for NFYA
- OriGene qPCR primer pairs and template standards for NFYA
- OriGene CRISPR knockouts for NFYA
- MG204581
- MG223083
- MR204581
- MR204581L3
- MR204581L4
- MR223083
- MR223083L3
- MR223083L4
- RC205981
- RC205981L3
- RC205981L4
- RC213263
- RC213263L1
- RC213263L2
- RC213263L3
- RC213263L4
- RG205981
- RG213263
- RR211726
- RR211726L3
- RR211726L4
- MR204581L3V
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- RC205981L3V
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- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For NFYA
- Sino Biological Human cDNA Clone for NFYA
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- Sino Biological Antibodies for NFYA
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- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for NFYA
- Novus Biologicals proteins and lysates for NFYA
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- Abcam antibodies for NFYA
- Abcam proteins for NFYA
- Abcam assays for NFYA
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- Browse Primary Antibodies
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- Invitrogen Antibodies for NFYA (AFLGC-NFYA)
- VectorBuilder Custom and pre-made DNA vectors for NFYA (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for NFYA (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for NFYA (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for NFYA CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for NFYA
- antibodies-online: Show 42 available NFYA Antibodies ranked by validation data
- antibodies-online: Show 3 available NFYA Elisa Kits ranked by validation data
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- antibodies-online: Show 12 available NFYA Proteins ranked by validation data
- Compare Top NFYA Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for NFYA
- Search Santa Cruz Biotechnology (SCBT) for NFYA siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for NFYA
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for NFYA
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for NFYA
- Search GeneCopoeia for miRNA 3'UTR Target clone products for NFYA
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NFYA
- Biorbyt antibodies for NFYA
Sources for NFYA Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Apr-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) ASD
- (27) SAGE
- (28) SOURCE
- (29) HomoloGene
- (30) PanEnsembl
- (31) euGenes
- (32) SGD
- (33) FlyBase
- (34) WormBase
- (35) Pseudogene
- (36) DGV
- (37) dbSNP
- (38) GenAtlas
- (39) HGMD
- (40) GAD
- (41) BGMUT
- (42) HuGE
- (43) Atlas
- (44) GenBank
- (45) HORDE
- (46) HUGE
- (47) IMGT
- (48) Leiden
- (49) miRBase
- (50) DME
- (51) OriGene
- (52) PubMed
- (53) R&D Systems
- (54) Tocris
- (55) Abcam
- (56) Novus Biologicals
- (57) ProSpec
- (58) Sino Biological
- (59) GenScript
- (60) Qiagen
- (61) OCA
- (62) Proteopedia
- (63) MOPED
- (64) neXtProt
- (65) Reactome
- (66) GeneGo (Thomson Reuters)
- (67) DISEASES
- (68) SIMAP
- (69) GenomeRNAi
- (70) LifeMap
- (71) miRTarBase
- (72) MalaCards
- (73) Invitrogen
- (74) BitterDB
- (75) ESI-BIO
- (76) RefSeq
- (77) BioSystems
- (78) MaxQB
- (79) IUPHAR
- (80) BioGPS
- (81) Illumina
- (82) COMPARTMENTS
- (83) HOMER
- (84) PaxDb
- (85) ApexBio
- (86) Addgene
- (87) antibodies-online
- (88) CYP
- (89) NONCODE
- (90) TreeFam
- (91) PathCards
- (92) GeneReviews
- (93) GeneTex
- (94) Taconic Biosciences
- (95) GTEx
- (96) ProteomicsDB
- (97) SCBT
- (98) DGIdb
- (99) ClinicalTrials
- (100) RVIS
- (101) SIGNOR
- (102) diseasecard
- (103) NIH Rare Diseases
- (104) Orphanet
- (105) UMLS
- (106) GTR
- (107) Disease Ontology
- (108) MedlinePlus Genetics
- (109) MeSH
- (110) MedlinePlus
- (111) CDC
- (112) NINDS
- (113) NCBI Bookshelf
- (114) ClinVar
- (115) Gene Damage Index
- (116) HPO
- (117) UDN
- (118) VISTA
- (119) FANTOM5
- (120) ENCODE
- (121) ProSci
- (122) Horizon
- (123) The Signaling Pathways Project (SPP)
- (124) IID
- (125) VectorBuilder
- (126) SNPedia
- (127) BRCA Exchange
- (128) CIViC
- (129) ProteoGenix
- (130) dbSUPER
- (131) TISSUES
- (132) Gene ORGANizer
- (133) abm
- (134) Human Protein Atlas
- (135) GWAS Catalog
- (136) Monarch Initiative
- (137) DataMed
- (138) HumanCyc
- (139) UCNEbase
- (140) EPDnew
- (141) Applied Biosystems
- (142) GlyConnect
- (143) Aminode
- (144) GeneCopoeia
- (145) GPS-Prot
- (146) RNAcentral
- (147) LncRNADisease
- (148) LOVD
- (149) miR2Disease
- (150) DiseaseEnhancer
- (151) Boster Bio
- (152) Biorbyt
- (153) Biocompare
- (154) Mastermind
- (155) CTD^2 Dashboard
- (156) CraniofacialAtlas
- (157) GeneImprint
- (158) Synthego
- (159) ENA
- (160) GtRNAdb
- (161) LncBase
- (162) LncBook
- (163) LNCipedia
- (164) Modomics
- (165) PDBe
- (166) Rfam
- (167) SILVA
- (168) snOPY
- (169) SRPDB
- (170) GENCODE
- (171) TarBase
- (172) Open Targets Platform
- (173) 5SRRNADB
- (174) snoDB
- (175) MirGeneDB
- (176) Alliance of Genome Resources