Aliases for NFKBIL1 Gene
External Ids for NFKBIL1 Gene
Previous HGNC Symbols for NFKBIL1 Gene
Previous GeneCards Identifiers for NFKBIL1 Gene
This gene encodes a divergent member of the I-kappa-B family of proteins. Its function has not been determined. The gene lies within the major histocompatibility complex (MHC) class I region on chromosome 6. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2009]
GeneCards Summary for NFKBIL1 Gene
UniProtKB/Swiss-Prot Summary for NFKBIL1 Gene
Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon-regulatory factor (IRF) signaling pathways. Contributes to the negative regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli.