Aliases for NFIB Gene
External Ids for NFIB Gene
Previous GeneCards Identifiers for NFIB Gene
GeneCards Summary for NFIB Gene
NFIB (Nuclear Factor I B) is a Protein Coding gene. Diseases associated with NFIB include Breast Adenoid Cystic Carcinoma and Lacrimal System Cancer. Among its related pathways are RNA Polymerase III Transcription Initiation and FOXA1 transcription factor network. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding. An important paralog of this gene is NFIA.
UniProtKB/Swiss-Prot for NFIB Gene
Recognizes and binds the palindromic sequence 5-TTGGCNNNNNGCCAA-3 present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.