Aliases for NEUROG2 Gene
External Ids for NEUROG2 Gene
Previous GeneCards Identifiers for NEUROG2 Gene
This gene encodes a neural-specific basic helix-loop-helix (bHLH) transcription factor that can specify a neuronal fate on ectodermal cells and is expressed in neural progenitor cells within the developing central and peripheral nervous systems. The protein product of this gene also plays a role in the differentiation and survival of midbrain dopaminergic neurons. [provided by RefSeq, Apr 2012]
GeneCards Summary for NEUROG2 Gene
NEUROG2 (Neurogenin 2) is a Protein Coding gene. Diseases associated with NEUROG2 include Retinitis Pigmentosa 58 and Neuropathy, Hereditary Sensory And Autonomic, Type Iii. Among its related pathways are Dopaminergic Neurogenesis and Neuroscience. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding and E-box binding. An important paralog of this gene is NEUROG1.
UniProtKB/Swiss-Prot Summary for NEUROG2 Gene
Transcriptional regulator. Involved in neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3').