Aliases for NEU2 Gene
External Ids for NEU2 Gene
Previous GeneCards Identifiers for NEU2 Gene
This gene belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. Expression studies in COS7 cells confirmed that this gene encodes a functional sialidase. Its cytosolic localization was demonstrated by cell fractionation experiments. [provided by RefSeq, Jul 2008]
GeneCards Summary for NEU2 Gene
NEU2 (Neuraminidase 2) is a Protein Coding gene. Diseases associated with NEU2 include Discrete Subaortic Stenosis and Cardiomyopathy, Dilated, 1G. Among its related pathways are Metabolism of proteins and Sphingolipid metabolism. Gene Ontology (GO) annotations related to this gene include exo-alpha-(2->3)-sialidase activity and exo-alpha-(2->8)-sialidase activity. An important paralog of this gene is NEU4.
UniProtKB/Swiss-Prot Summary for NEU2 Gene
Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moieties from glycoproteins, oligosaccharides and gangliosides.