Aliases for NDUFS6 Gene
Aliases for NDUFS6 Gene
- NADH:Ubiquinone Oxidoreductase Subunit S6 2 3 5
- NADH Dehydrogenase (Ubiquinone) Fe-S Protein 6, 13kDa (NADH-Coenzyme Q Reductase) 2 3
- NADH Dehydrogenase [Ubiquinone] Iron-Sulfur Protein 6, Mitochondrial 2 3
- NADH-Ubiquinone Oxidoreductase 13 KDa-A Subunit 3 4
- Complex I 13kDa Subunit A 2 3
- CI-13kD-A 3 4
- NADH Dehydrogenase (Ubiquinone) Fe-S Protein 6 (13kD) (NADH-Coenzyme Q Reductase) 2
External Ids for NDUFS6 Gene
- HGNC: 7713
- Entrez Gene: 4726
- Ensembl: ENSG00000145494
- OMIM: 603848
- UniProtKB: O75380
Previous GeneCards Identifiers for NDUFS6 Gene
- GC05P001942
- GC05P001834
- GC05P001854
Summaries for NDUFS6 Gene
-
This gene encodes a subunit of the NADH:ubiquinone oxidoreductase (complex I), which is the first enzyme complex in the electron transport chain of mitochondria. This complex functions in the transfer of electrons from NADH to the respiratory chain. The subunit encoded by this gene is one of seven subunits in the iron-sulfur protein fraction. Mutations in this gene cause mitochondrial complex I deficiency, a disease that causes a wide variety of clinical disorders, including neonatal disease and adult-onset neurodegenerative disorders.[provided by RefSeq, Oct 2009]
GeneCards Summary for NDUFS6 Gene
NDUFS6 (NADH:Ubiquinone Oxidoreductase Subunit S6) is a Protein Coding gene. Diseases associated with NDUFS6 include Mitochondrial Complex I Deficiency and Leigh Syndrome. Among its related pathways are Metformin Pathway, Pharmacodynamics and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. Gene Ontology (GO) annotations related to this gene include electron transfer activity and NADH dehydrogenase (ubiquinone) activity.
UniProtKB/Swiss-Prot for NDUFS6 Gene
-
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Additional gene information for NDUFS6 Gene
- Monarch Initiative
- Search for NDUFS6 at DataMed
- Search for NDUFS6 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NDUFS6 Gene
Genomics for NDUFS6 Gene
GeneHancer (GH) Regulatory Elements for NDUFS6 Gene
Promoters and enhancers for NDUFS6 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around NDUFS6 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for NDUFS6 Gene
Genomic Locations for NDUFS6 Gene
- chr5:1,801,382-1,816,605
- (GRCh38/hg38)
- Size:
- 15,224 bases
- Orientation:
- Plus strand
- chr5:1,801,496-1,816,719
- (GRCh37/hg19)
Genomic View for NDUFS6 Gene
Genes around NDUFS6 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 5p15.33 by Ensembl
- 5p15.33 by Entrez Gene
- 5p15.33 by HGNC
NDUFS6 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for NDUFS6 Gene
Proteins for NDUFS6 Gene
-
Protein details for NDUFS6 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O75380-NDUS6_HUMAN
- Recommended name:
- NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial
- Protein Accession:
- O75380
Protein attributes for NDUFS6 Gene
- Size:
- 124 amino acids
- Molecular mass:
- 13712 Da
- Quaternary structure:
-
- Mammalian complex I is composed of 45 different subunits (PubMed:12611891, PubMed:27626371). This is a component of the iron-sulfur (IP) fragment of the enzyme (PubMed:12611891).
Protein Expression for NDUFS6 Gene
Post-translational modifications for NDUFS6 Gene
No Post-translational modifications
Other Protein References for NDUFS6 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
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-
Abcam antibodies for NDUFS6
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-
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Assay Products
No data available for DME Specific Peptides for NDUFS6 Gene
Domains & Families for NDUFS6 Gene
Gene Families for NDUFS6 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
Suggested Antigen Peptide Sequences for NDUFS6 Gene
Graphical View of Domain Structure for InterPro Entry
O75380- Family:
-
- Belongs to the complex I NDUFS6 subunit family.
Function for NDUFS6 Gene
Molecular function for NDUFS6 Gene
- GENATLAS Biochemistry:
- NADH ubiquinone oxidoreductase (Q reductase),13kDa,component of the complex I multi-subunit enzyme of the oxidative phosphorylation (OXPHOS),iron-sulfur protein 6,inner mitochondrial membrane
- UniProtKB/Swiss-Prot Function:
- Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0008137 | NADH dehydrogenase (ubiquinone) activity | NAS | 9647766 |
| GO:0009055 | electron transfer activity | NAS | 9647766 |
Phenotypes for NDUFS6 Gene
- MGI mutant phenotypes for NDUFS6:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for NDUFS6:
Animal Model Products
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miRNA for NDUFS6 Gene
- miRTarBase miRNAs that target NDUFS6
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-
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- Mammalian expression: PiggyBac
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- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
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No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Animal Models , Transcription Factor Targets and HOMER Transcription for NDUFS6 Gene
Localization for NDUFS6 Gene
Subcellular locations from UniProtKB/Swiss-Prot for NDUFS6 Gene
- Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
| Compartment | Confidence |
|---|---|
| mitochondrion | 5 |
| plasma membrane | 1 |
| extracellular | 1 |
| nucleus | 1 |
| cytosol | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005743 | mitochondrial inner membrane | TAS | -- |
| GO:0005747 | mitochondrial respiratory chain complex I | NAS | 9878551 |
| GO:0016020 | membrane | IEA | -- |
| GO:0070469 | respiratory chain | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for NDUFS6 Gene
Pathways & Interactions for NDUFS6 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | ||
| 2 | Metabolism |
.37
|
|
| 3 | GABAergic synapse | ||
| 4 | Metformin Pathway, Pharmacodynamics | ||
Pathways by source for NDUFS6 Gene
2 BioSystems pathways for NDUFS6 Gene
1 PharmGKB pathway for NDUFS6 Gene
7 KEGG pathways for NDUFS6 Gene
Interacting Proteins for NDUFS6 Gene
Selected Interacting proteins:
ENSP00000274137
O75380-NDUS6_HUMAN
for NDUFS6 Gene via
STRING
IID
MINT
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006120 | mitochondrial electron transport, NADH to ubiquinone | IBA,TAS | -- |
| GO:0006631 | fatty acid metabolic process | IEA | -- |
| GO:0006936 | muscle contraction | IEA | -- |
| GO:0010259 | multicellular organism aging | IEA | -- |
| GO:0022904 | respiratory electron transport chain | IEA | -- |
No data available for SIGNOR curated interactions for NDUFS6 Gene
Drugs & Compounds for NDUFS6 Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| Fe2+ |
|
15438-31-0 |
|
|||
| QH2 |
|
56275-39-9 |
|
|||
| Sulfide |
|
18496-25-8 |
|
Transcripts for NDUFS6 Gene
mRNA/cDNA for NDUFS6 Gene
- (1) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (234) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for NDUFS6 Gene
CRISPR Products
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Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for NDUFS6
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miRNA Products
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Inhibitory RNA Products
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-
ViGene Biosciences ready-to-package AAV shRNAs for NDUFS6 gene
Clone Products
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available NDUFS6 gene related products
- orf clones - Search results for available NDUFS6 gene related products
- Applied Biological Materials Clones for NDUFS6
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for NDUFS6 Gene
mRNA differential expression in normal tissues according to GTEx for NDUFS6 Gene
This gene is overexpressed in Heart - Left Ventricle (x4.1).
This gene is overexpressed in Heart (11.2), Peripheral blood mononuclear cells (7.4), and Brain (7.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for NDUFS6 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of NDUFS6 Gene:
NDUFS6SOURCE GeneReport for Unigene cluster for NDUFS6 Gene:
Hs.408257Evidence on tissue expression from TISSUES for NDUFS6 Gene
- Liver(4.4)
- Lung(4.3)
- Skin(4.3)
- Heart(2.3)
- Muscle(2.2)
Phenotype-based relationships between genes and organs from Gene ORGANizer for NDUFS6 Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- cardiovascular
- digestive
- endocrine
- integumentary
- nervous
- respiratory
- skeletal muscle
- skeleton
Regions:
Head and neck:
- brain
- cerebellum
- cerebrospinal fluid
- cranial nerve
- ear
- eye
- eyelid
- face
- head
- meninges
- neck
- skull
Thorax:
- esophagus
- heart
- heart valve
- lung
Abdomen:
- adrenal gland
- liver
- stomach
Limb:
- foot
- lower limb
General:
- peripheral nerve
- peripheral nervous system
- skin
- spinal cord
- sweat gland
Primer Products
-
OriGene qPCR primer pairs and template standards for NDUFS6
-
OriGene qPCR primer pairs for NDUFS6
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No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for NDUFS6 Gene
Orthologs for NDUFS6 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | NDUFS6 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | NDUFS6 34 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | NDUFS6 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Ndufs6 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | LOC679739 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | -- 34 |
|
OneToMany | |
| -- 34 |
|
OneToMany | |||
| -- 34 |
|
OneToMany | |||
| platypus (Ornithorhynchus anatinus) |
Mammalia | NDUFS6 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | NDUFS6 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | NDUFS6 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | ndufs6 33 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.7070 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | ndufs6 33 34 |
|
||
| Dr.15123 33 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | CG8680 33 34 |
|
||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP009072 33 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | nduf-6 33 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.5753 34 |
|
OneToOne |
- Species where no ortholog for NDUFS6 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for NDUFS6 Gene
Pseudogenes.org Pseudogenes for NDUFS6 Gene
No data available for Paralogs for NDUFS6 Gene
Variants for NDUFS6 Gene
| SNP ID | Clin | Chr 05 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs10058270 | likely-benign, Mitochondrial complex I deficiency | 1,815,836(+) | T/C | intron_variant | |
| rs140887831 | uncertain-significance, Mitochondrial complex I deficiency | 1,814,350(+) | C/T | coding_sequence_variant, synonymous_variant | |
| rs145747389 | benign, uncertain-significance, not specified, Mitochondrial complex I deficiency | 1,801,406(+) | C/T | 5_prime_UTR_variant | |
| rs200445799 | uncertain-significance, likely-benign, Mitochondrial complex I deficiency, not specified | 1,815,931(+) | C/T | 3_prime_UTR_variant | |
| rs267606913 | pathogenic, Mitochondrial complex I deficiency, Mitochondrial complex I deficiency (MT-C1D) [MIM:252010] | 1,815,885(+) | G/A | coding_sequence_variant, missense_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1140355 | OTHER | inversion | 24896259 |
| nsv1033147 | CNV | gain | 25217958 |
| esv3603817 | CNV | gain | 21293372 |
Residual Variation Intolerance Score:
49.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.68;
14.47% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for NDUFS6 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NDUFS6 Gene
Disorders for NDUFS6 Gene
(4) MalaCards diseases for NDUFS6 Gene - From: HGMD, OMIM, ClinVar, GTR, Swiss-Prot, DISEASES, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| mitochondrial complex i deficiency |
|
|
| leigh syndrome |
|
|
| leber hereditary optic neuropathy |
|
|
| mitochondrial metabolism disease |
|
|
Search NDUFS6 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
NDUS6_HUMAN- Mitochondrial complex I deficiency (MT-C1D) [MIM:252010]: A disorder of the mitochondrial respiratory chain that causes a wide range of clinical manifestations from lethal neonatal disease to adult-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease. {ECO:0000269 PubMed:15372108, ECO:0000269 PubMed:19259137}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for NDUFS6
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for Genatlas for NDUFS6 Gene
Publications for NDUFS6 Gene
- Accessory subunits are integral for assembly and function of human mitochondrial complex I. (PMID: 27626371) Stroud DA … Ryan MT (Nature 2016) 3 4 58
- Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson SL … O'Brien SJ (PloS one 2010) 3 44 58
- Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. (PMID: 19343046) Saito A … Kamatani N (Journal of human genetics 2009) 3 44 58
- Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey. (PMID: 18977241) Starr JM … Deary IJ (Mechanisms of ageing and development 2008) 3 44 58
- Polymorphisms in mitochondrial genes and prostate cancer risk. (PMID: 19064571) Wang L … Thibodeau SN (Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008) 3 44 58
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- Search GeneTex for Proteins for NDUFS6
- ViGene Biosciences adenoviral particle packaged cDNA for NDUFS6 gene
- ViGene Biosciences lentiviral particle packaged cDNA for NDUFS6 gene
- ViGene Biosciences ready-to-package AAV shRNAs for NDUFS6 gene
- Search ViGene Biosciences for NDUFS6
- Horizon Cell Lines for NDUFS6
- genomics-online: cdna clones - Search results for available NDUFS6 gene related products
- orf clones - Search results for available NDUFS6 gene related products
- genomics-online: gRNA clones - Search results for available NDUFS6 gene related products
- genomics-online: primer clones - Search results for available NDUFS6 gene related products
- genomics-online: shRNA clones - Search results for available NDUFS6 gene related products
Sources for NDUFS6 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew