Aliases for NDUFB7 Gene
External Ids for NDUFB7 Gene
Previous GeneCards Identifiers for NDUFB7 Gene
The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. It is located at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. [provided by RefSeq, Jul 2008]
GeneCards Summary for NDUFB7 Gene
NDUFB7 (NADH:Ubiquinone Oxidoreductase Subunit B7) is a Protein Coding gene. Diseases associated with NDUFB7 include Codas Syndrome and Mitochondrial Dna Depletion Syndrome 9. Among its related pathways are GABAergic synapse and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. Gene Ontology (GO) annotations related to this gene include NADH dehydrogenase (ubiquinone) activity and NADH dehydrogenase activity.
UniProtKB/Swiss-Prot Summary for NDUFB7 Gene
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.