Aliases for NDUFB5 Gene
Aliases for NDUFB5 Gene
External Ids for NDUFB5 Gene
- HGNC: 7700
- Entrez Gene: 4711
- Ensembl: ENSG00000136521
- OMIM: 603841
- UniProtKB: O43674
Previous GeneCards Identifiers for NDUFB5 Gene
- GC03P176087
- GC03P180165
- GC03P180724
- GC03P180643
- GC03P180805
- GC03P179322
- GC03P176726
Summaries for NDUFB5 Gene
-
The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
GeneCards Summary for NDUFB5 Gene
NDUFB5 (NADH:Ubiquinone Oxidoreductase Subunit B5) is a Protein Coding gene. Among its related pathways are Metabolism and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. Gene Ontology (GO) annotations related to this gene include NADH dehydrogenase (ubiquinone) activity.
UniProtKB/Swiss-Prot for NDUFB5 Gene
-
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Additional gene information for NDUFB5 Gene
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NDUFB5 Gene
Genomics for NDUFB5 Gene
GeneHancer (GH) Regulatory Elements for NDUFB5 Gene
Promoters and enhancers for NDUFB5 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH03J179603 | Promoter/Enhancer | 2 | EPDnew Ensembl ENCODE | 659.6 | -0.1 | -93 | 2.4 | PKNOX1 SMAD1 ARNT ARID4B SIN3A DMAP1 ZNF2 IRF4 YY1 POLR2B | NDUFB5 MRPL47 TTC14 USP13 ACTL6A MFN1 ENSG00000272660 | |
| GH03J179612 | Enhancer | 0.9 | ENCODE | 9.7 | +9.8 | 9774 | 3.2 | HDAC1 ATF1 ARNT NCOA2 CHAMP1 TCF12 ATF7 CREM CEBPB NCOA1 | ENSG00000239096 USP13 NDUFB5 | |
| GH03J179608 | Enhancer | 0.8 | Ensembl ENCODE | 6.5 | +4.4 | 4411 | 1.2 | CBFA2T3 ELF1 BATF NFATC1 ZFP91 KDM1A ZBTB33 ATF7 RUNX3 SPI1 | USP13 MRPL47 NDUFB5 ENSG00000239096 | |
| GH03J179525 | Enhancer | 0.9 | Ensembl ENCODE | 4.8 | -77.8 | -77764 | 2.3 | CEBPG ZIC2 RAD21 YY1 ETS1 POLR2A ZNF143 CHD2 NANOG L3MBTL2 | ENSG00000239255 GNB4 NDUFB5 ACTL6A PIR62273 | |
| GH03J179626 | Enhancer | 0.4 | ENCODE | 8.8 | +22.6 | 22593 | 1.1 | ATF4 ATF2 | GC03P179625 USP13 NDUFB5 MRPL47 GC03P179640 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around NDUFB5 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the NDUFB5 gene promoter:
-
- Nkx2-2
- MIF-1
- HFH-1
- COMP1
- Evi-1
- HOXA9
- HOXA9B
- Meis-1b
- Meis-1
Regulatory Element Products
Genomic Locations for NDUFB5 Gene
Genomic Locations for NDUFB5 Gene
- chr3:179,604,690-179,627,647
- (GRCh38/hg38)
- Size:
- 22,958 bases
- Orientation:
- Plus strand
- chr3:179,322,478-179,345,435
- (GRCh37/hg19)
- Size:
- 22,958 bases
- Orientation:
- Plus strand
Genomic View for NDUFB5 Gene
Genes around NDUFB5 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 3q26.33 by Entrez Gene
- 3q26.33 by HGNC
- 3q26.33 by Ensembl
NDUFB5 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for NDUFB5 Gene
Proteins for NDUFB5 Gene
-
Protein details for NDUFB5 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O43674-NDUB5_HUMAN
- Recommended name:
- NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial
- Protein Accession:
- O43674
- Q561V6
Protein attributes for NDUFB5 Gene
- Size:
- 189 amino acids
- Molecular mass:
- 21750 Da
- Quaternary structure:
-
- Complex I is composed of 45 different subunits.
Three dimensional structures from OCA and Proteopedia for NDUFB5 Gene
Protein Expression for NDUFB5 Gene
Post-translational modifications for NDUFB5 Gene
Other Protein References for NDUFB5 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for NDUFB5
- Novus Biologicals Antibodies for NDUFB5
-
Abcam antibodies for NDUFB5
- Invitrogen Antibodies for NDUFB5 (AFLGC-NDUFB5)
- GeneTex NDUFB5 Antibody for NDUFB5
-
Boster Bio Antibodies for NDUFB5
-
Santa Cruz Biotechnology (SCBT) Antibodies for NDUFB5
Protein Products
-
OriGene Purified Proteins for NDUFB5
- Search Origene for MassSpec and Protein Over-expression Lysates for NDUFB5
- Origene Custom Protein Services for NDUFB5
- antibodies-online: Search results for 4 available NDUFB5 Proteins ranked by validation data
- Compare Top NDUFB5 Proteins
-
Quality Products:
- Search GeneTex for Proteins for NDUFB5
-
Abcam proteins for NDUFB5
Assay Products
No data available for DME Specific Peptides for NDUFB5 Gene
Domains & Families for NDUFB5 Gene
Gene Families for NDUFB5 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Predicted membrane proteins
- Predicted secreted proteins
Protein Domains for NDUFB5 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for NDUFB5 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
O43674- Family:
-
- Belongs to the complex I NDUFB5 subunit family.
Function for NDUFB5 Gene
Molecular function for NDUFB5 Gene
- UniProtKB/Swiss-Prot Function:
- Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0008137 | NADH dehydrogenase (ubiquinone) activity | NAS,TAS | 9878551 |
Phenotypes for NDUFB5 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for NDUFB5
-
CRISPR Products
-
OriGene CRISPR knockouts for NDUFB5
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for NDUFB5
- genomics-online: gRNA clones - Search results for 114 available NDUFB5 gene related products
- Overview of 114 available NDUFB5 gene related products
- Applied Biological Materials CRISPR for NDUFB5
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for NDUFB5
- GenScript: Design CRISPR guide RNA sequences for NDUFB5
miRNA for NDUFB5 Gene
- miRTarBase miRNAs that target NDUFB5
-
- hsa-mir-590-3p (MIRT016164)
- hsa-mir-221-3p (MIRT024139)
- hsa-mir-26b-5p (MIRT028994)
- hsa-mir-571 (MIRT377479)
- hsa-mir-659-3p (MIRT377480)
- hsa-mir-1303 (MIRT377481)
- hsa-mir-302c-5p (MIRT486392)
- hsa-mir-218-1-3p (MIRT486393)
- hsa-mir-3143 (MIRT486394)
- hsa-mir-3688-3p (MIRT486395)
- hsa-mir-543 (MIRT486396)
- hsa-mir-607 (MIRT549921)
- hsa-mir-3671 (MIRT549922)
- hsa-mir-591 (MIRT549923)
- hsa-mir-29a-5p (MIRT549924)
- hsa-mir-4528 (MIRT549925)
- hsa-mir-6074 (MIRT549926)
- hsa-mir-4272 (MIRT549927)
- hsa-mir-10b-5p (MIRT549928)
- hsa-mir-10a-5p (MIRT549929)
- hsa-mir-6512-5p (MIRT549930)
- hsa-mir-504-5p (MIRT549931)
- hsa-mir-6736-5p (MIRT617568)
- hsa-mir-4701-3p (MIRT617569)
- hsa-mir-1262 (MIRT617570)
- hsa-mir-7703 (MIRT617571)
- hsa-mir-6720-5p (MIRT617572)
- hsa-mir-6512-3p (MIRT617573)
- hsa-mir-661 (MIRT617574)
- hsa-mir-4696 (MIRT617575)
- hsa-mir-642b-3p (MIRT617576)
- hsa-mir-642a-3p (MIRT617577)
- hsa-mir-6776-5p (MIRT617578)
- hsa-mir-4793-3p (MIRT617579)
- hsa-mir-766-3p (MIRT617580)
- hsa-mir-372-5p (MIRT617581)
- hsa-mir-371a-5p (MIRT617582)
- hsa-mir-616-5p (MIRT617583)
- hsa-mir-373-5p (MIRT617584)
- hsa-mir-371b-5p (MIRT617585)
- hsa-mir-6742-3p (MIRT617586)
- hsa-mir-6849-3p (MIRT617587)
- hsa-mir-451b (MIRT617588)
- hsa-mir-508-5p (MIRT617589)
- hsa-mir-3120-3p (MIRT617590)
- hsa-mir-4432 (MIRT617591)
- hsa-mir-4776-3p (MIRT643089)
- hsa-mir-4642 (MIRT643090)
- hsa-mir-6805-3p (MIRT643091)
- hsa-mir-5691 (MIRT643092)
- hsa-mir-4659b-5p (MIRT643093)
- hsa-mir-4659a-5p (MIRT643094)
- hsa-mir-5590-5p (MIRT643095)
- hsa-mir-6873-3p (MIRT643096)
- hsa-mir-4279 (MIRT643097)
- hsa-mir-6792-3p (MIRT643098)
- hsa-mir-4691-5p (MIRT643099)
- hsa-mir-891a-3p (MIRT643100)
- hsa-mir-3688-5p (MIRT643101)
- hsa-mir-6817-3p (MIRT643102)
- hsa-mir-7110-3p (MIRT643103)
- hsa-mir-6769b-3p (MIRT643104)
- hsa-mir-4723-3p (MIRT643105)
- hsa-mir-3183 (MIRT643106)
- hsa-mir-3607-5p (MIRT643107)
- hsa-mir-6800-3p (MIRT643108)
- hsa-mir-187-3p (MIRT783996)
- hsa-mir-3177-5p (MIRT784743)
- hsa-mir-574-5p (MIRT787872)
- hsa-mir-6867-5p (MIRT789212)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for NDUFB5
- Browse OriGene Inhibitory RNA Products For NDUFB5
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NDUFB5
- genomics-online: shRNA clones - Search results for 114 available NDUFB5 gene related products
- Overview of 114 available NDUFB5 gene related products
Clone Products
- Sino Biological Human cDNA Clone for NDUFB5
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for NDUFB5
- Applied Biological Materials Clones for NDUFB5
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for NDUFB5
No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for NDUFB5 Gene
Localization for NDUFB5 Gene
Subcellular locations from UniProtKB/Swiss-Prot for NDUFB5 Gene
- Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
| Compartment | Confidence |
|---|---|
| mitochondrion | 5 |
| nucleus | 5 |
| cytosol | 2 |
- Mitochondria (3)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0005739 | mitochondrion | IDA | -- |
| GO:0005743 | mitochondrial inner membrane | TAS | -- |
| GO:0005747 | mitochondrial respiratory chain complex I | NAS | 9878551 |
| GO:0016020 | membrane | IEA | -- |
Pathways & Interactions for NDUFB5 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
.40
|
|
| 2 | Metabolism |
.37
|
|
| 3 | GABAergic synapse | ||
Pathways by source for NDUFB5 Gene
2 BioSystems pathways for NDUFB5 Gene
8 KEGG pathways for NDUFB5 Gene
Interacting Proteins for NDUFB5 Gene
GPS-Prot Interaction Network for NDUFB5
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006120 | mitochondrial electron transport, NADH to ubiquinone | TAS | -- |
| GO:0032981 | mitochondrial respiratory chain complex I assembly | TAS | -- |
| GO:0055114 | oxidation-reduction process | IEA | -- |
No data available for SIGNOR curated interactions for NDUFB5 Gene
Drugs & Compounds for NDUFB5 Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| Fe2+ |
|
15438-31-0 |
|
|||
| QH2 |
|
56275-39-9 |
|
|||
| Sulfide |
|
18496-25-8 |
|
Drug Products
Transcripts for NDUFB5 Gene
mRNA/cDNA for NDUFB5 Gene
- (3) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (690) Selected AceView cDNA sequences:
- (16) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000488002 842 bps (uc062qfp.1)
- ENST00000259037 1141 bps (uc003fkc.4)
- ENST00000493866 4046 bps (uc003fke.4)
- ENST00000472629 744 bps (uc062qfq.1)
- ENST00000468210 824 bps (uc062qfr.1)
Unigene Clusters for NDUFB5 Gene
CRISPR Products
-
OriGene CRISPR knockouts for NDUFB5
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for NDUFB5
- genomics-online: gRNA clones - Search results for 114 available NDUFB5 gene related products
- Overview of 114 available NDUFB5 gene related products
- Applied Biological Materials CRISPR for NDUFB5
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for NDUFB5
- GenScript: Design CRISPR guide RNA sequences for NDUFB5
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for NDUFB5
- Browse OriGene Inhibitory RNA Products For NDUFB5
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NDUFB5
- genomics-online: shRNA clones - Search results for 114 available NDUFB5 gene related products
- Overview of 114 available NDUFB5 gene related products
Clone Products
- Sino Biological Human cDNA Clone for NDUFB5
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for NDUFB5
- Applied Biological Materials Clones for NDUFB5
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | · | 1f | · | 1g | · | 1h | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | · | 8c | · | 8d | · | 8e | · | 8f | · | 8g | · | 8h |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP10: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | - | - |
Expression for NDUFB5 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
- Intestine (Gastrointestinal Tract)
-
Colon (Gastrointestinal Tract)
-
Prostate (Endocrine System)
-
Placenta (Extraembryonic Tissues)
-
Spleen (Hematopoietic System)
-
Thyroid (Endocrine System)
-
Gall Bladder (Hepatobiliary System)
-
Kidney (Urinary System)
-
Testis (Reproductive System)
-
Adrenal Gland (Endocrine System)
-
Esophagus (Gastrointestinal Tract)
-
Stomach (Gastrointestinal Tract)
-
Liver (Hepatobiliary System)
-
Ovary (Reproductive System)
-
Adipose (Muscoskeletal System)
This gene is overexpressed in Nasal epithelium (16.0), Heart (8.2), and Peripheral blood mononuclear cells (6.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for NDUFB5 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of NDUFB5 Gene:
NDUFB5SOURCE GeneReport for Unigene cluster for NDUFB5 Gene:
Hs.730674Evidence on tissue expression from TISSUES for NDUFB5 Gene
- Nervous system(4.9)
- Heart(4.6)
- Skin(4.5)
- Liver(4.3)
- Muscle(2.9)
- Kidney(2.8)
- Lung(2.5)
Primer Products
-
OriGene qPCR primer pairs for NDUFB5
-
OriGene qPCR primer pairs and template standards for NDUFB5
- genomics-online: primer clones - Search results for 114 available NDUFB5 gene related products
- Overview of 114 available NDUFB5 gene related products
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for NDUFB5 Gene
Orthologs for NDUFB5 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | NDUFB5 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | NDUFB5 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | NDUFB5 34 33 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Ndufb5 16 34 33 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Ndufb5 33 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | NDUFB5 34 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | NDUFB5 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | NDUFB5 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | NDUFB5 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | ndufb5 33 |
|
||
| Str.1944 33 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | ndufb5-prov 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | ndufb5 34 33 |
|
OneToOne | |
| -- 33 |
|
||||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.8572 33 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | l(3)neo18 34 33 |
|
OneToOne | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP007297 33 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.3719 34 |
|
OneToOne |
- Species where no ortholog for NDUFB5 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for NDUFB5 Gene
- ENSEMBL:
- Gene Tree for NDUFB5 (if available)
- TreeFam:
- Gene Tree for NDUFB5 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for NDUFB5: view image
Paralogs for NDUFB5 Gene
Pseudogenes.org Pseudogenes for NDUFB5 Gene
No data available for Paralogs for NDUFB5 Gene
Variants for NDUFB5 Gene
| SNP ID | Clin | Chr 03 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000033690 | -- | 179,616,149(+) | A/T | intron_variant | |
| rs1000149418 | -- | 179,615,856(+) | T/C | intron_variant | |
| rs1000396752 | -- | 179,608,837(+) | T/A | intron_variant | |
| rs1000456215 | -- | 179,615,778(+) | T/C | intron_variant | |
| rs1000504213 | -- | 179,622,315(+) | T/C | intron_variant |
Residual Variation Intolerance Score:
65.6% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for NDUFB5 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- NDUFB5
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for NDUFB5 Gene
Disorders for NDUFB5 Gene
Additional Disease Information for NDUFB5
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for NDUFB5 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NDUFB5 Gene
Publications for NDUFB5 Gene
- Identification and primary structure of five human NADH-ubiquinone oxidoreductase subunits. (PMID: 9425316) Ton C … Liew CC (Biochemical and biophysical research communications 1997) 2 3 4 58
- Accessory subunits are integral for assembly and function of human mitochondrial complex I. (PMID: 27626371) Stroud DA … Ryan MT (Nature 2016) 3 4 58
- Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson SL … O'Brien SJ (PloS one 2010) 3 44 58
- Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. (PMID: 19343046) Saito A … Kamatani N (Journal of human genetics 2009) 3 44 58
- Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey. (PMID: 18977241) Starr JM … Deary IJ (Mechanisms of ageing and development 2008) 3 44 58
Products for NDUFB5 Gene
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- antibodies-online: Search results for 22 available NDUFB5 Antibodies ranked by validation data
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- Quality Products:
- GeneTex NDUFB5 Antibody for NDUFB5
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- Santa Cruz Biotechnology (SCBT) Antibodies for NDUFB5
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- genomics-online: cdna clones - Search results for 114 available NDUFB5 gene related products
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- Overview of 114 available NDUFB5 gene related products
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Sources for NDUFB5 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
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- (123) CDC
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- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt