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NDUFB1 (NADH:Ubiquinone Oxidoreductase Subunit B1) is a Protein Coding gene. Diseases associated with NDUFB1 include Bacterial Gastritis and Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis. Among its related pathways are GABAergic synapse and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. Gene Ontology (GO) annotations related to this gene include NADH dehydrogenase (ubiquinone) activity and NADH dehydrogenase activity.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003954 | NADH dehydrogenase activity | IEA | -- |
GO:0008137 | NADH dehydrogenase (ubiquinone) activity | TAS,NAS | 9878551 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005739 | mitochondrion | IDA | -- |
GO:0005743 | mitochondrial inner membrane | TAS | -- |
GO:0005747 | mitochondrial respiratory chain complex I | NAS | 9878551 |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
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2 | Parkinson disease | ||
3 | Metabolism |
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4 | GABAergic synapse |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006120 | mitochondrial electron transport, NADH to ubiquinone | TAS | -- |
GO:0032981 | mitochondrial respiratory chain complex I assembly | TAS | -- |
GO:0055114 | oxidation-reduction process | IEA | -- |
Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
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QH2 |
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56275-39-9 |
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Sulfide |
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18496-25-8 |
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This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
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Chimpanzee (Pan troglodytes) |
Mammalia | NDUFB1 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | NDUFB1 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | LOC102631912 30 |
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Ndufb1 17 |
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Dog (Canis familiaris) |
Mammalia | LOC102156783 30 |
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Oppossum (Monodelphis domestica) |
Mammalia | NDUFB1 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | NDUFB1 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | NDUFB1 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | NDUFB1 31 |
|
OneToOne | |
African clawed frog (Xenopus laevis) |
Amphibia | Xl.6643 30 |
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Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | Str.3020 30 |
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Zebrafish (Danio rerio) |
Actinopterygii | NDUFB1 31 |
|
OneToOne |
Disorder | Aliases | PubMed IDs |
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bacterial gastritis |
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sensory ataxic neuropathy, dysarthria, and ophthalmoparesis |
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visual epilepsy |
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