Aliases for NCR3LG1 Gene
External Ids for NCR3LG1 Gene
Previous GeneCards Identifiers for NCR3LG1 Gene
B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity (Brandt et al., 2009 [PubMed 19528259]).[supplied by OMIM, Jan 2011]
GeneCards Summary for NCR3LG1 Gene
NCR3LG1 (Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1) is a Protein Coding gene. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. Gene Ontology (GO) annotations related to this gene include structural molecule activity. An important paralog of this gene is TAPBPL.
UniProtKB/Swiss-Prot Summary for NCR3LG1 Gene
Triggers NCR3-dependent natural killer cell activation.