Aliases for NCMAP Gene

Aliases for NCMAP Gene

  • Non-Compact Myelin Associated Protein 2 3 5
  • Myelin Protein Of 11 KDa 2 3 4
  • Noncompact Myelin-Associated Protein 3 4
  • C1orf130 3 4
  • MP11 3 4
  • Chromosome 1 Open Reading Frame 130 2

External Ids for NCMAP Gene

Previous HGNC Symbols for NCMAP Gene

  • C1orf130

Previous GeneCards Identifiers for NCMAP Gene

  • GC01P024883

Summaries for NCMAP Gene

GeneCards Summary for NCMAP Gene

NCMAP (Non-Compact Myelin Associated Protein) is a Protein Coding gene. Diseases associated with NCMAP include Dieulafoy Lesion. Gene Ontology (GO) annotations related to this gene include structural constituent of myelin sheath.

UniProtKB/Swiss-Prot Summary for NCMAP Gene

Additional gene information for NCMAP Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for NCMAP Gene

Genomics for NCMAP Gene

GeneHancer (GH) Regulatory Elements for NCMAP Gene

Promoters and enhancers for NCMAP Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J024555 Promoter/Enhancer 1.6 EPDnew Ensembl ENCODE dbSUPER 520.2 +0.8 847 3.5 POLR2G ZIC2 ZBTB26 EZH2 CTCF SRSF1 CREB1 SAP130 MXD4 HDAC1 NCMAP NCMAP-DT RCAN3 RPL26P8
GH01J024589 Promoter 0.5 EPDnew 512 +33.4 33421 0.1 ZNF341 EGR2 NCMAP SRRM1 RCAN3 piR-50437-021 ENSG00000239106
GH01J024641 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas 15.3 +87.3 87260 4.3 HNRNPK ZNF217 EP300 NRF1 POLR2G USF1 SP1 PHF8 ZFX ZNF639 SRRM1 SRSF10 SYF2 RPL11 PNRC2 ELOA NCMAP ENSG00000261349 FUCA1 RUNX3
GH01J024501 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 11.4 -51.0 -50993 7.9 EP300 HNRNPK NRF1 POLR2G USF1 GTF2E2 PHF8 ZNF10 POLR2A ZBTB10 RCAN3 NCMAP SYF2 CLIC4 NIPAL3 STPG1 GRHL3 RUNX3 SRRM1 lnc-STPG1-4
GH01J024587 Enhancer 1 Ensembl ENCODE 25.7 +31.2 31236 0.6 ZNF217 CTCF REST ZBTB25 RAD21 TRIM22 SMC3 SAP130 MIER3 NR2F2 NCMAP SRRM1 RCAN3 piR-50437-021 ENSG00000239106
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around NCMAP on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for NCMAP

Genomic Locations for NCMAP Gene

Genomic Locations for NCMAP Gene
chr1:24,556,076-24,609,328
(GRCh38/hg38)
Size:
53,253 bases
Orientation:
Plus strand
chr1:24,882,602-24,935,819
(GRCh37/hg19)
Size:
53,218 bases
Orientation:
Plus strand

Genomic View for NCMAP Gene

Genes around NCMAP on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NCMAP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NCMAP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NCMAP Gene

Proteins for NCMAP Gene

  • Protein details for NCMAP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T1S8-NCMAP_HUMAN
    Recommended name:
    Noncompact myelin-associated protein
    Protein Accession:
    Q5T1S8
    Secondary Accessions:
    • A0PK04
    • B2RV34

    Protein attributes for NCMAP Gene

    Size:
    102 amino acids
    Molecular mass:
    11082 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NCMAP Gene

Post-translational modifications for NCMAP Gene

Other Protein References for NCMAP Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for NCMAP Gene

Domains & Families for NCMAP Gene

Gene Families for NCMAP Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for NCMAP Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with NCMAP: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for NCMAP Gene

Function for NCMAP Gene

Molecular function for NCMAP Gene

UniProtKB/Swiss-Prot Function:
Plays a role in myelin formation.

Phenotypes From GWAS Catalog for NCMAP Gene

Gene Ontology (GO) - Molecular Function for NCMAP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0019911 structural constituent of myelin sheath ISS --
genes like me logo Genes that share ontologies with NCMAP: view
genes like me logo Genes that share phenotypes with NCMAP: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for NCMAP Gene

Localization for NCMAP Gene

Subcellular locations from UniProtKB/Swiss-Prot for NCMAP Gene

Cell membrane; Single-pass type I membrane protein. Note=Localized mainly in the Schmidt-Lanterman incisures and paranodes of noncompact peripheral nerve myelin. {ECO:0000250}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for NCMAP gene
Compartment Confidence
plasma membrane 4
nucleus 2
cytosol 2
extracellular 1
mitochondrion 1
golgi apparatus 1
peroxisome 0

Gene Ontology (GO) - Cellular Components for NCMAP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005887 integral component of plasma membrane ISS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0033270 paranode region of axon ISS,IBA --
GO:0043220 Schmidt-Lanterman incisure IBA,ISS --
genes like me logo Genes that share ontologies with NCMAP: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for NCMAP Gene

Pathways & Interactions for NCMAP Gene

PathCards logo

SuperPathways for NCMAP Gene

No Data Available

Interacting Proteins for NCMAP Gene

;

Gene Ontology (GO) - Biological Process for NCMAP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0031641 regulation of myelination IEA --
GO:0031643 positive regulation of myelination ISS --
GO:0032290 peripheral nervous system myelin formation ISS,IBA --
genes like me logo Genes that share ontologies with NCMAP: view

No data available for Pathways by source and SIGNOR curated interactions for NCMAP Gene

Drugs & Compounds for NCMAP Gene

No Compound Related Data Available

Transcripts for NCMAP Gene

mRNA/cDNA for NCMAP Gene

1 REFSEQ mRNAs :
6 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for NCMAP Gene

ExUns: 1 ^ 2a · 2b ^ 3a · 3b · 3c
SP1: -
SP2: -
SP3:

Relevant External Links for NCMAP Gene

GeneLoc Exon Structure for
NCMAP

Expression for NCMAP Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for NCMAP Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for NCMAP Gene

This gene is overexpressed in Nerve - Tibial (x31.1) and Pancreas (x4.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for NCMAP Gene



Transcriptomic regulation report from SPP (The Signaling Pathways Project) for NCMAP

SOURCE GeneReport for Unigene cluster for NCMAP Gene:

Hs.200253

Evidence on tissue expression from TISSUES for NCMAP Gene

  • Nervous system(4)
genes like me logo Genes that share expression patterns with NCMAP: view

No data available for Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for NCMAP Gene

Orthologs for NCMAP Gene

This gene was present in the common ancestor of mammals.

Orthologs for NCMAP Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia NCMAP 31 30
  • 99.35 (n)
OneToOne
dog
(Canis familiaris)
Mammalia NCMAP 31 30
  • 89.77 (n)
OneToOne
cow
(Bos Taurus)
Mammalia NCMAP 31 30
  • 88.24 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Ncmap 17 31 30
  • 84.67 (n)
rat
(Rattus norvegicus)
Mammalia Ncmap 30
  • 84 (n)
oppossum
(Monodelphis domestica)
Mammalia NCMAP 31
  • 63 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia NCMAP 31
  • 57 (a)
OneToOne
Species where no ortholog for NCMAP was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NCMAP Gene

ENSEMBL:
Gene Tree for NCMAP (if available)
TreeFam:
Gene Tree for NCMAP (if available)
Aminode:
Evolutionary constrained regions (ECRs) for NCMAP: view image

Paralogs for NCMAP Gene

No data available for Paralogs for NCMAP Gene

Variants for NCMAP Gene

Additional dbSNP identifiers (rs#s) for NCMAP Gene

Structural Variations from Database of Genomic Variants (DGV) for NCMAP Gene

Variant ID Type Subtype PubMed ID
dgv31e199 CNV deletion 23128226
esv1961948 CNV deletion 18987734
esv2665308 CNV deletion 23128226
esv27046 CNV loss 19812545
esv3585506 CNV loss 21293372
nsv1140258 OTHER inversion 24896259
nsv1147629 CNV deletion 26484159
nsv436645 CNV deletion 17901297
nsv545823 CNV gain 21841781
nsv834458 CNV loss 17160897

Variation tolerance for NCMAP Gene

Residual Variation Intolerance Score: 79.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.16; 51.72% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for NCMAP Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
NCMAP

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for NCMAP Gene

Disorders for NCMAP Gene

MalaCards: The human disease database

(1) MalaCards diseases for NCMAP Gene - From: DISEASES

Disorder Aliases PubMed IDs
dieulafoy lesion
  • dieulafoy lesion of intestine
- elite association - COSMIC cancer census association via MalaCards
Search NCMAP in MalaCards View complete list of genes associated with diseases

Additional Disease Information for NCMAP

genes like me logo Genes that share disorders with NCMAP: view

No data available for UniProtKB/Swiss-Prot and Genatlas for NCMAP Gene

Publications for NCMAP Gene

  1. Analysis of peripheral nerve expression profiles identifies a novel myelin glycoprotein, MP11. (PMID: 18650334) Ryu EJ … Milbrandt J (The Journal of neuroscience : the official journal of the Society for Neuroscience 2008) 2 3 54
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 3 4 54
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 54
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3 54
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 54

Products for NCMAP Gene

Sources for NCMAP Gene