Aliases for NCEH1 Gene
External Ids for NCEH1 Gene
Previous HGNC Symbols for NCEH1 Gene
Previous GeneCards Identifiers for NCEH1 Gene
GeneCards Summary for NCEH1 Gene
NCEH1 (Neutral Cholesterol Ester Hydrolase 1) is a Protein Coding gene. Among its related pathways are Lipoprotein metabolism and Aldosterone synthesis and secretion. Gene Ontology (GO) annotations related to this gene include hydrolase activity and phosphate ion binding. An important paralog of this gene is AADAC.
UniProtKB/Swiss-Prot Summary for NCEH1 Gene
Hydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. May be responsible for cholesterol ester hydrolysis in macrophages, thereby contributing to the development of atherosclerosis. Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds. May contribute to cancer pathogenesis by promoting tumor cell migration.