Aliases for NCBP2AS2 Gene

Aliases for NCBP2AS2 Gene

  • NCBP2 Antisense 2 (Head To Head) 2 3 5
  • Hypoxia-Induced Angiogenesis Regulator 2 3 4
  • HIAR 2 3 4
  • NCBP2 Antisense RNA 2 (Head To Head) 2 3
  • NCBP2 Antisense Gene Protein 2 3 4
  • KRAS-Interacting Microprotein 2 3
  • Protein NCBP2AS2 3 4
  • KRASIM 2 3
  • NCBP2-AS2 3
  • NCBP2AS2 5

External Ids for NCBP2AS2 Gene

Previous HGNC Symbols for NCBP2AS2 Gene

  • NCBP2-AS2

Summaries for NCBP2AS2 Gene

GeneCards Summary for NCBP2AS2 Gene

NCBP2AS2 (NCBP2 Antisense 2 (Head To Head)) is a Protein Coding gene.

Additional gene information for NCBP2AS2 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for NCBP2AS2 Gene

Genomics for NCBP2AS2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for NCBP2AS2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03J196938 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas 635.7 -0.3 -273 7.6 SP1 HNRNPL CREB1 GATAD2A CTCF PRDM10 ZNF629 TFE3 SIX5 LEF1 NCBP2AS2 NCBP2 NONHSAG037132.2 SDHAP1 RPL17P18 PIGZ SENP5 ENSG00000214135 NCBP2-AS1 ENSG00000230732
GH03J196866 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 29.1 -74.0 -73975 3.8 SP1 CREB1 HNRNPL SIX5 IKZF1 POLR2A BACH1 JUND LARP7 MTA2 SENP5 lnc-NCBP2-1 NCBP2AS2 RPL36P7 NCBP2 NCBP2-AS1 CEP19 HE856253
GH03J196919 Enhancer 0.6 Ensembl 32 -22.2 -22173 2.2 IKZF2 TRIM22 PKNOX1 NBN ESR1 NR2F1 SPI1 BATF MTA2 HNF4A NCBP2AS2 NCBP2-AS1 HSALNG0031973 ENSG00000230732 NCBP2 SENP5
GH03J196968 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 6.9 +26.4 26427 3 HNRNPL CTCF BACH1 TARDBP LARP7 MTA2 ZNF143 ZIC2 RBFOX2 PATZ1 PIGZ MN298070 lnc-PIGZ-1 SDHAP1 ENSG00000214135 LRCH3 UBXN7 RPL17P18 SENP5 RPL35A
GH03J196939 Enhancer 0.3 Ensembl 34.1 -4.4 -4373 0.2 NFE2 EMSY NCBP2-AS1 NCBP2AS2 NCBP2 piR-36886 SENP5
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around NCBP2AS2 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for NCBP2AS2

Genomic Locations for NCBP2AS2 Gene

Genomic Locations for NCBP2AS2 Gene
chr3:196,942,674-196,943,543
(GRCh38/hg38)
Size:
870 bases
Orientation:
Plus strand
chr3:196,669,494-196,670,884
(GRCh37/hg19)
Size:
1,391 bases
Orientation:
Plus strand

Genomic View for NCBP2AS2 Gene

Genes around NCBP2AS2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NCBP2AS2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NCBP2AS2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NCBP2AS2 Gene

Proteins for NCBP2AS2 Gene

  • Protein details for NCBP2AS2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q69YL0-NCAS2_HUMAN
    Recommended name:
    Protein NCBP2AS2
    Protein Accession:
    Q69YL0

    Protein attributes for NCBP2AS2 Gene

    Size:
    99 amino acids
    Molecular mass:
    10891 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • Induced by hypoxia in cancer-associated fibroblasts and promotes tumor angiogenesis by causing increased secretion of VEGFA which leads to endothelial sprouting.

neXtProt entry for NCBP2AS2 Gene

Post-translational modifications for NCBP2AS2 Gene

No Post-translational modifications

Other Protein References for NCBP2AS2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for NCBP2AS2 Gene

Domains & Families for NCBP2AS2 Gene

Gene Families for NCBP2AS2 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for NCBP2AS2 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with NCBP2AS2: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for NCBP2AS2 Gene

Function for NCBP2AS2 Gene

Phenotypes From GWAS Catalog for NCBP2AS2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NCBP2AS2 Gene

Localization for NCBP2AS2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for NCBP2AS2 Gene

Pathways & Interactions for NCBP2AS2 Gene

PathCards logo

SuperPathways for NCBP2AS2 Gene

No Data Available

Interacting Proteins for NCBP2AS2 Gene

Gene Ontology (GO) - Biological Process for NCBP2AS2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for NCBP2AS2 Gene

Drugs & Compounds for NCBP2AS2 Gene

No Compound Related Data Available

Transcripts for NCBP2AS2 Gene

mRNA/cDNA for NCBP2AS2 Gene

1 REFSEQ mRNAs :
6 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for NCBP2AS2 Gene

No ASD Table

Relevant External Links for NCBP2AS2 Gene

GeneLoc Exon Structure for
NCBP2AS2

Expression for NCBP2AS2 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for NCBP2AS2

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NCBP2AS2 Gene

Orthologs for NCBP2AS2 Gene

Evolution for NCBP2AS2 Gene

ENSEMBL:
Gene Tree for NCBP2AS2 (if available)
TreeFam:
Gene Tree for NCBP2AS2 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for NCBP2AS2: view image

No data available for Orthologs for NCBP2AS2 Gene

Paralogs for NCBP2AS2 Gene

No data available for Paralogs for NCBP2AS2 Gene

Variants for NCBP2AS2 Gene

Additional dbSNP identifiers (rs#s) for NCBP2AS2 Gene

Structural Variations from Database of Genomic Variants (DGV) for NCBP2AS2 Gene

Variant ID Type Subtype PubMed ID
esv2763775 CNV gain+loss 21179565
esv3599293 CNV gain 21293372
nsv1003135 CNV gain 25217958
nsv593086 CNV loss 21841781

Additional Variant Information for NCBP2AS2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
NCBP2AS2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for NCBP2AS2 Gene

Disorders for NCBP2AS2 Gene

No disorders were found for NCBP2AS2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NCBP2AS2 Gene

Publications for NCBP2AS2 Gene

  1. Hypoxic cancer-associated fibroblasts increase NCBP2-AS2/HIAR to promote endothelial sprouting through enhanced VEGF signaling. (PMID: 30723174) Kugeratski FG … Zanivan S (Science signaling 2019) 2 3 4
  2. Ribosome profiling analysis identified a KRAS-interacting microprotein that represses oncogenic signaling in hepatocellular carcinoma cells. (PMID: 31240521) Xu W … Qu L (Science China. Life sciences 2020) 2 3
  3. A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
  4. H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids. (PMID: 30804502) Nakamura K … Groth A (Nature cell biology 2019) 3
  5. N-terminome analysis of the human mitochondrial proteome. (PMID: 25944712) Vaca Jacome AS … Carapito C (Proteomics 2015) 4

Products for NCBP2AS2 Gene

Sources for NCBP2AS2 Gene