NCBP2AS2 Gene (Protein Coding)

NCBP2 Antisense 2 (Head To Head)

GC03P196944
GIFtS:
15

Aliases for NCBP2AS2 Gene

Aliases for NCBP2AS2 Gene

  • NCBP2 Antisense 2 (Head To Head) 2 3 5
  • Hypoxia-Induced Angiogenesis Regulator 2 3 4
  • NCBP2 Antisense RNA 2 (Head To Head) 2 3
  • NCBP2 Antisense Gene Protein 2 3 4
  • KRAS-Interacting Microprotein 2 3
  • Protein NCBP2AS2 3 4
  • HIAR 3 4
  • NCBP2-AS2 3
  • KRASIM 3

External Ids for NCBP2AS2 Gene

Previous HGNC Symbols for NCBP2AS2 Gene

  • NCBP2-AS2

Summaries for NCBP2AS2 Gene

GeneCards Summary for NCBP2AS2 Gene

NCBP2AS2 (NCBP2 Antisense 2 (Head To Head)) is a Protein Coding gene.

Additional gene information for NCBP2AS2 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for NCBP2AS2 Gene

Genomics for NCBP2AS2 Gene

GeneHancer (GH) Regulatory Elements for NCBP2AS2 Gene

Promoters and enhancers for NCBP2AS2 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH03J196938 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas 785.6 -0.2 -222 7.6 ZNF24 SP1 ZBTB40 CTCF SIX5 MLX SMARCE1 RBPJ POLR2A USF2 NCBP2AS2 NCBP2 NONHSAG037132.2 SDHAP1 ENSG00000234742 RNF168 SENP5 LRCH3 ENSG00000230732 UBXN7
GH03J196866 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 29.1 -73.9 -73924 3.8 SP1 ZBTB40 SIX5 RBPJ POLR2A ATF1 CREB1 HCFC1 MYC NFYC SENP5 lnc-NCBP2-1 NCBP2AS2 RNF168 RPL36P7 SDHAP1 NCBP2 ENSG00000234742 NCBP2-AS1 PCYT1A
GH03J196919 Enhancer 0.5 Ensembl 32 -22.1 -22122 2.2 ZNF217 IKZF1 IKZF2 PKNOX1 TRIM22 NR2F1 NBN BATF HNF4A NCBP2AS2 NCBP2-AS1 ENSG00000230732 HSALNG0031973 SENP5
GH03J196968 Promoter/Enhancer 2.3 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 6.9 +26.5 26478 3 ZBTB40 CTCF POLR2A MYC L3MBTL2 MAX RAD21 MNT ZKSCAN8 NKRF PIGZ lnc-PIGZ-1 UBXN7 SDHAP1 ENSG00000214135 LRCH3 UBXN7-AS1 ENSG00000234742 SENP5 WDR53
GH03J196939 Enhancer 0.3 Ensembl 34.1 -4.3 -4322 0.2 NFE2 EMSY NCBP2-AS1 NCBP2AS2 NCBP2 piR-36886
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around NCBP2AS2 on UCSC Golden Path with GeneCards custom track

Genomic Locations for NCBP2AS2 Gene

Genomic Locations for NCBP2AS2 Gene
chr3:196,942,623-196,944,013
(GRCh38/hg38)
Size:
1,391 bases
Orientation:
Plus strand
chr3:196,669,494-196,670,884
(GRCh37/hg19)
Size:
1,391 bases
Orientation:
Plus strand

Genomic View for NCBP2AS2 Gene

Genes around NCBP2AS2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NCBP2AS2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NCBP2AS2 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for NCBP2AS2 Gene

Proteins for NCBP2AS2 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for NCBP2AS2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q69YL0-NCAS2_HUMAN
    Recommended name:
    Protein NCBP2AS2
    Protein Accession:
    Q69YL0

    Protein attributes for NCBP2AS2 Gene

    Size:
    99 amino acids
    Molecular mass:
    10891 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • Induced by hypoxia in cancer-associated fibroblasts and promotes tumor angiogenesis by causing increased secretion of VEGFA which leads to endothelial sprouting.

neXtProt entry for NCBP2AS2 Gene

Post-translational modifications for NCBP2AS2 Gene

No Post-translational modifications

Other Protein References for NCBP2AS2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for NCBP2AS2 Gene

Domains & Families for NCBP2AS2 Gene

Gene Families for NCBP2AS2 Gene

Human Protein Atlas (HPA):
  • Predicted secreted proteins

Protein Domains for NCBP2AS2 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with NCBP2AS2: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for NCBP2AS2 Gene

Function for NCBP2AS2 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Phenotypes From GWAS Catalog for NCBP2AS2 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NCBP2AS2 Gene

Localization for NCBP2AS2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for NCBP2AS2 Gene

Pathways & Interactions for NCBP2AS2 Gene

PathCards logo

SuperPathways for NCBP2AS2 Gene

No Data Available

Interacting Proteins for NCBP2AS2 Gene

Selected Interacting proteins: Q69YL0-NCAS2_HUMAN for NCBP2AS2 Gene via IID

GPS-Prot Interaction Network for NCBP2AS2

Gene Ontology (GO) - Biological Process for NCBP2AS2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for NCBP2AS2 Gene

Drugs & Compounds for NCBP2AS2 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for NCBP2AS2 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for NCBP2AS2 Gene

(1) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(100) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for NCBP2AS2 Gene

No ASD Table

Relevant External Links for NCBP2AS2 Gene

GeneLoc Exon Structure for
NCBP2AS2
ECgene alternative splicing isoforms for
NCBP2AS2

Expression for NCBP2AS2 Gene

Products:

  1. Primer
No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NCBP2AS2 Gene

Orthologs for NCBP2AS2 Gene

Evolution for NCBP2AS2 Gene

ENSEMBL:
Gene Tree for NCBP2AS2 (if available)
TreeFam:
Gene Tree for NCBP2AS2 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for NCBP2AS2: view image

No data available for Orthologs for NCBP2AS2 Gene

Paralogs for NCBP2AS2 Gene

No data available for Paralogs for NCBP2AS2 Gene

Variants for NCBP2AS2 Gene

Sequence variations from dbSNP and Humsavar for NCBP2AS2 Gene

SNP ID Clin Chr 03 pos Variation AA Info Type
rs1000108563 -- 196,941,161(+) G/A/T upstream_transcript_variant
rs1000807537 -- 196,940,812(+) T/G upstream_transcript_variant
rs1000859702 -- 196,941,070(+) T/G upstream_transcript_variant
rs1001237265 -- 196,941,428(+) C/G upstream_transcript_variant
rs1001268638 -- 196,941,693(+) C/G/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for NCBP2AS2 Gene

Variant ID Type Subtype PubMed ID
esv2763775 CNV gain+loss 21179565
esv3599293 CNV gain 21293372
nsv1003135 CNV gain 25217958
nsv593086 CNV loss 21841781

Additional Variant Information for NCBP2AS2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
NCBP2AS2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for NCBP2AS2 Gene

Disorders for NCBP2AS2 Gene

No disorders were found for NCBP2AS2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for NCBP2AS2 Gene

Publications for NCBP2AS2 Gene

  1. Hypoxic cancer-associated fibroblasts increase NCBP2-AS2/HIAR to promote endothelial sprouting through enhanced VEGF signaling. (PMID: 30723174) Kugeratski FG … Zanivan S (Science signaling 2019) 2 3 4 56
  2. Ribosome profiling analysis identified a KRAS-interacting microprotein that represses oncogenic signaling in hepatocellular carcinoma cells. (PMID: 31240521) Xu W … Qu L (Science China. Life sciences 2019) 2 3 56
  3. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein MY … Mann M (Cell 2015) 3 56
  4. N-terminome analysis of the human mitochondrial proteome. (PMID: 25944712) Vaca Jacome AS … Carapito C (Proteomics 2015) 4 56
  5. An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells. (PMID: 21319273) Neganova I … Lako M (Stem cells (Dayton, Ohio) 2011) 3 56

ExternalLinks

View latest publications for NCBP2AS2 gene in Mastermind

Products for NCBP2AS2 Gene

Sources for NCBP2AS2 Gene