Aliases for NCAPG2 Gene
External Ids for NCAPG2 Gene
Previous HGNC Symbols for NCAPG2 Gene
Previous GeneCards Identifiers for NCAPG2 Gene
This gene encodes a protein that belongs to the Condensin2nSMC family of proteins. The encoded protein is a regulatory subunit of the condensin II complex which, along with the condensin I complex, plays a role in chromosome assembly and segregation during mitosis. A similar protein in mouse is required for early development of the embryo. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
GeneCards Summary for NCAPG2 Gene
NCAPG2 (Non-SMC Condensin II Complex Subunit G2) is a Protein Coding gene. Diseases associated with NCAPG2 include Khan-Khan-Katsanis Syndrome and Pleural Empyema. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and Mesodermal Commitment Pathway. Gene Ontology (GO) annotations related to this gene include binding and methylated histone binding.
UniProtKB/Swiss-Prot Summary for NCAPG2 Gene
Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis.