Aliases for NCAPG Gene
External Ids for NCAPG Gene
Previous GeneCards Identifiers for NCAPG Gene
This gene encodes a subunit of the condensin complex, which is responsible for the condensation and stabilization of chromosomes during mitosis and meiosis. Phosphorylation of the encoded protein activates the condensin complex. There are pseudogenes for this gene on chromosomes 8 and 15. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
GeneCards Summary for NCAPG Gene
NCAPG (Non-SMC Condensin I Complex Subunit G) is a Protein Coding gene. Diseases associated with NCAPG include Uterine Corpus Endometrial Carcinoma. Among its related pathways are Mitotic Prometaphase and Aurora B signaling. Gene Ontology (GO) annotations related to this gene include binding.
UniProtKB/Swiss-Prot for NCAPG Gene
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.