Aliases for NCAPD3 Gene
External Ids for NCAPD3 Gene
Previous GeneCards Identifiers for NCAPD3 Gene
Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Both condensins contain 2 invariant structural maintenance of chromosome (SMC) subunits, SMC2 (MIM 605576) and SMC4 (MIM 605575), but they contain different sets of non-SMC subunits. NCAPD3 is 1 of 3 non-SMC subunits that define condensin II (Ono et al., 2003 [PubMed 14532007]).[supplied by OMIM, Mar 2008]
GeneCards Summary for NCAPD3 Gene
NCAPD3 (Non-SMC Condensin II Complex Subunit D3) is a Protein Coding gene. Diseases associated with NCAPD3 include Microcephaly 22, Primary, Autosomal Recessive. Among its related pathways are Cell Cycle, Mitotic and Cell cycle_Chromosome condensation in prometaphase. Gene Ontology (GO) annotations related to this gene include binding and methylated histone binding.
UniProtKB/Swiss-Prot for NCAPD3 Gene
Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis.