Aliases for NBPF19 Gene

Aliases for NBPF19 Gene

  • NBPF Member 19 2 3 5
  • Neuroblastoma Breakpoint Family Member 19 3 4
  • Neuroblastoma Breakpoint Family, Member 19 2
  • NBPF19 5

External Ids for NBPF19 Gene

Previous GeneCards Identifiers for NBPF19 Gene

  • GC01U901195
  • GC01P149473
  • GC01P149511

Summaries for NBPF19 Gene

GeneCards Summary for NBPF19 Gene

NBPF19 (NBPF Member 19) is a Protein Coding gene. Diseases associated with NBPF19 include Neuroblastoma and Familial Adult Myoclonic Epilepsy. An important paralog of this gene is ENSG00000286185.

Additional gene information for NBPF19 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for NBPF19 Gene

Genomics for NBPF19 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for NBPF19 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J149475 Enhancer 0.2 Ensembl 600.7 +0.2 202 1.5 NBPF19 piR-34965-014 piR-58037-012 piR-55397-012 HSALNG0006650-010 ENSG00000286185 PPIAL4C
GH01J149428 Promoter 0.3 Ensembl 0.3 -46.2 -46237 0.2 piR-46583-005 piR-40331-005 ENSG00000286185 NOTCH2NLC NBPF19
GH01J149423 Promoter 0.3 Ensembl 0.2 -52.2 -52237 0.2 piR-46583-005 piR-40331-005 ENSG00000286185 NOTCH2NLC NBPF19
GH01J149424 Promoter 0.3 Ensembl 0.2 -51.6 -51637 0.6 piR-46583-005 piR-40331-005 ENSG00000286185 NOTCH2NLC NBPF19
GH01J149463 Enhancer 0.2 Ensembl 0.4 -7.1 -7085 10.1 piR-37475-005 piR-38380-005 piR-47635-005 piR-39259-004 piR-55736-004 piR-49296-005 piR-47741-005 piR-51314-004 NBPF19 NOTCH2NLC
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around NBPF19 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for NBPF19

Genomic Locations for NBPF19 Gene

Genomic Locations for NBPF19 Gene
81,024 bases
Plus strand

Genomic View for NBPF19 Gene

Genes around NBPF19 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NBPF19 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NBPF19 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NBPF19 Gene

Proteins for NBPF19 Gene

  • Protein details for NBPF19 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Neuroblastoma breakpoint family member 19
    Protein Accession:

    Protein attributes for NBPF19 Gene

    3843 amino acids
    Molecular mass:
    440408 Da
    Quaternary structure:
    No Data Available
    • Encoded by one of the numerous copies of NBPF genes clustered in the p36, p12 and q21 region of the chromosome 1.

neXtProt entry for NBPF19 Gene

Post-translational modifications for NBPF19 Gene

Other Protein References for NBPF19 Gene

No data available for DME Specific Peptides for NBPF19 Gene

Domains & Families for NBPF19 Gene

Gene Families for NBPF19 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for NBPF19 Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the NBPF family.
  • Belongs to the NBPF family.
genes like me logo Genes that share domains with NBPF19: view

No data available for Suggested Antigen Peptide Sequences for NBPF19 Gene

Function for NBPF19 Gene

Phenotypes From GWAS Catalog for NBPF19 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NBPF19 Gene

Localization for NBPF19 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NBPF19 Gene

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nuclear bodies (2)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for NBPF19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with NBPF19: view

No data available for Subcellular locations from COMPARTMENTS for NBPF19 Gene

Pathways & Interactions for NBPF19 Gene

PathCards logo

SuperPathways for NBPF19 Gene

No Data Available

Interacting Proteins for NBPF19 Gene

Selected Interacting proteins: A0A087WUL8-NBPFJ_HUMAN for NBPF19 Gene via IID

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for NBPF19 Gene


No data available for Pathways by source and SIGNOR curated interactions for NBPF19 Gene

Drugs & Compounds for NBPF19 Gene

No Compound Related Data Available

Transcripts for NBPF19 Gene

mRNA/cDNA for NBPF19 Gene

6 NCBI additional mRNA sequence :
5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for NBPF19 Gene

No ASD Table

Relevant External Links for NBPF19 Gene

GeneLoc Exon Structure for

Expression for NBPF19 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NBPF19 Gene

Orthologs for NBPF19 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for NBPF19 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC458021 30
  • 83.55 (n)
Species where no ortholog for NBPF19 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for NBPF19 Gene

Gene Tree for NBPF19 (if available)
Gene Tree for NBPF19 (if available)

Paralogs for NBPF19 Gene

genes like me logo Genes that share paralogs with NBPF19: view

Variants for NBPF19 Gene

Additional dbSNP identifiers (rs#s) for NBPF19 Gene

Additional Variant Information for NBPF19 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for NBPF19 Gene

Disorders for NBPF19 Gene

MalaCards: The human disease database

(2) MalaCards diseases for NBPF19 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
  • nb
familial adult myoclonic epilepsy
  • adcme
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for NBPF19

genes like me logo Genes that share disorders with NBPF19: view

No data available for UniProtKB/Swiss-Prot and Genatlas for NBPF19 Gene

Publications for NBPF19 Gene

  1. A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution. (PMID: 16079250) Vandepoele K … van Roy F (Molecular biology and evolution 2005) 2 3
  2. A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
  3. RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. (PMID: 29117863) Choudhury NR … Michlewski G (BMC biology 2017) 3
  4. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 4
  5. Lineage-specific gene duplication and loss in human and great ape evolution. (PMID: 15252450) Fortna A … Sikela JM (PLoS biology 2004) 3

Products for NBPF19 Gene

Sources for NBPF19 Gene