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This gene encodes a member of a large, diverse group of A-kinase anchor proteins that target the activity of protein kinase A to specific subcellular sites by binding to its type II regulatory subunits. Brain-specific expression and coat protein-like membrane recruitment of a highly similar protein in mouse suggest an involvement in neuronal post-Golgi membrane traffic. Mutatio... See more...
Aliases for NBEA Gene
Aliases for NBEA Gene
External Ids for NBEA Gene
- HGNC: 7648
- Entrez Gene: 26960
- Ensembl: ENSG00000172915
- OMIM: 604889
- UniProtKB: Q8NFP9
Previous GeneCards Identifiers for NBEA Gene
- GC13P033850
- GC13P029502
- GC13P034453
- GC13P033314
- GC13P034414
- GC13P035516
- GC13P016329
Summaries for NBEA Gene
-
This gene encodes a member of a large, diverse group of A-kinase anchor proteins that target the activity of protein kinase A to specific subcellular sites by binding to its type II regulatory subunits. Brain-specific expression and coat protein-like membrane recruitment of a highly similar protein in mouse suggest an involvement in neuronal post-Golgi membrane traffic. Mutations in this gene may be associated with a form of autism. This gene and its expression are frequently disrupted in patients with multiple myeloma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants may exist, but their full-length nature has not been determined.[provided by RefSeq, Feb 2011]
GeneCards Summary for NBEA Gene
NBEA (Neurobeachin) is a Protein Coding gene. Diseases associated with NBEA include Cerebellar, Ocular, Craniofacial, And Genital Syndrome and Autism. Gene Ontology (GO) annotations related to this gene include binding and phospholipid binding. An important paralog of this gene is LRBA.
UniProtKB/Swiss-Prot Summary for NBEA Gene
-
Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins (By similarity).
Additional gene information for NBEA Gene
- HGNC(7648)
- Entrez Gene(26960)
- Ensembl(ENSG00000172915)
- OMIM(604889)
- UniProtKB(Q8NFP9)
- Open Targets Platform(ENSG00000172915)
- Monarch Initiative
- Search for NBEA at DataMed
- Search for NBEA at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for NBEA Gene
Genomics for NBEA Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for NBEA Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH13J034941 | Promoter/Enhancer | 1.9 | EPDnew Ensembl ENCODE CraniofacialAtlas | 606.9 | +0.8 | 831 | 4.2 | PRDM10 KDM1A LARP7 PRDM1 ZNF143 ZIC2 RBFOX2 POLR2A PATZ1 ZNF501 | NBEA ENSG00000261728 piR-37972-153 MAB21L1 | |
| GH13J034913 | Enhancer | 0.7 | Ensembl ENCODE | 11.5 | -27.0 | -26970 | 5.4 | TEAD4 REST KDM1A YY1 SPI1 ETS1 SIN3A ZNF143 MIER2 NANOG | NBEA ENSG00000273886 ENSG00000261728 | |
| GH13J035198 | Enhancer | 0.8 | VISTA UCNEbase | 10.4 | +256.9 | 256939 | 2.1 | POLR2A | NBEA SCAND3P1 lnc-RFC3-11 HSALNG0096345 MAB21L1 | |
| GH13J034968 | Enhancer | 0.7 | Ensembl ENCODE | 11.3 | +25.9 | 25931 | 0.4 | PRDM1 ZNF341 OSR2 ZNF189 ZNF335 PRDM4 ZNF366 ZFP37 SP7 | NBEA piR-37972-153 MAB21L1 | |
| GH13J034155 | Enhancer | 1 | ENCODE dbSUPER | 6 | -785.6 | -785631 | 3.2 | CREB1 PRDM10 ZNF629 ZNF692 STAT3 PRDM1 RFX1 PATZ1 ZNF501 SCRT2 | lnc-STARD13-7 ENSG00000199196 NBEA lnc-STARD13-6 RFC3 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around NBEA on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for NBEA
- Top Transcription factor binding sites by QIAGEN in the NBEA gene promoter:
-
- AREB6
- ATF-2
- CRE-BP1
- E47
- NRSF form 1
- NRSF form 2
- Pax-2a
- TGIF
Genomic Locations for NBEA Gene
Genomic Locations for NBEA Gene
- chr13:34,942,270-35,673,022
- (GRCh38/hg38)
- Size:
- 730,753 bases
- Orientation:
- Plus strand
- chr13:35,516,424-36,247,159
- (GRCh37/hg19)
- Size:
- 730,736 bases
- Orientation:
- Plus strand
Genomic View for NBEA Gene
Genes around NBEA on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 13q13.3 by HGNC
- 13q13.3 by Entrez Gene
- 13q13.3 by Ensembl
NBEA Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for NBEA Gene
Proteins for NBEA Gene
-
Protein details for NBEA Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8NFP9-NBEA_HUMAN
- Recommended name:
- Neurobeachin
- Protein Accession:
- Q8NFP9
- B7Z2H9
- Q5T320
- Q9HCM8
- Q9NSU1
- Q9NW98
- Q9Y6J1
Protein attributes for NBEA Gene
- Size:
- 2946 amino acids
- Molecular mass:
- 327822 Da
- Quaternary structure:
-
- Interacts with RII subunit of PKA.
- SequenceCaution:
-
- Sequence=AAD41633.1; Type=Frameshift; Evidence={ECO:0000305}; Sequence=BAA91485.1; Type=Erroneous termination; Note=Truncated C-terminus.; Evidence={ECO:0000305};
Protein Expression for NBEA Gene
Selected DME Specific Peptides for NBEA Gene
- Q8NFP9:
-
- NLVTGGD
- AKLERAL
Post-translational modifications for NBEA Gene
Other Protein References for NBEA Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Creative Diagnostics Anti-NBEA monoclonal antibody, clone 4G22
- Creative Biolabs Mouse Anti-NBEA Recombinant Antibody (3F11)
- Novus Biologicals Antibodies for NBEA
-
Abcam antibodies for NBEA
- Invitrogen Antibodies for NBEA (AFLGC-NBEA)
Protein Products
-
OriGene Purified Proteins for NBEA
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-
Abcam proteins for NBEA
Assay Products
- antibodies-online: Show 5 available Neurobeachin Elisa Kits ranked by validation data
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-
Quality Products:
-
Signalway ELISA kits for NBEA
Domains & Families for NBEA Gene
Gene Families for NBEA Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
- Predicted membrane proteins
Protein Domains for NBEA Gene
- InterPro:
- Blocks:
-
- Beige/BEACH domain
- ProtoNet:
Suggested Antigen Peptide Sequences for NBEA Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ53986, highly similar to Protein neurobeachin (B7Z2H9_HUMAN)
- cDNA FLJ52700, highly similar to Protein neurobeachin (B7Z4S7_HUMAN)
- Protein BCL8B (NBEA_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q8NFP9UniProtKB/Swiss-Prot:
NBEA_HUMAN :- RII-alpha binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer.
- Belongs to the WD repeat neurobeachin family.
- Domain:
-
- RII-alpha binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer.
- Family:
-
- Belongs to the WD repeat neurobeachin family.
Function for NBEA Gene
Molecular function for NBEA Gene
- UniProtKB/Swiss-Prot Function:
- Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins (By similarity).
- GENATLAS Biochemistry:
- neurobeachin,cytosolic protein,specifically expressed in brain,peripherally associated with several membrane compartments including trans-Golgi network and endosome-like structures,may be involved in membrane trafficking events
Enzyme Numbers (IUBMB) for NBEA Gene
Phenotypes From GWAS Catalog for NBEA Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IEA | -- |
| GO:0019901 | protein kinase binding | IEA | -- |
Phenotypes for NBEA Gene
- MGI mutant phenotypes for NBEA:
-
inferred from 2 alleles
- nervous system phenotype
- respiratory system phenotype
- cardiovascular system phenotype
- behavior/neurological phenotype
- mortality/aging
- muscle phenotype
- homeostasis/metabolism phenotype
- growth/size/body region phenotype
- endocrine/exocrine gland phenotype
- integument phenotype
- embryo phenotype
- adipose tissue phenotype
- GenomeRNAi human phenotypes for NBEA:
-
- Increased vaccinia virus (VACV) infection
- no effect
- Resistant to vaccinia virus (VACV-A4L) infection
- shRNA abundance <= 50%
- Decreased viability ratio
- Decreased human papilloma virus 16 (HPV16) pseudovirus infection
- Increased S DNA content
- Increased G1 length
- Increased S length
- Increased viability
- Increased G1 length, increased S length, increased G2 length
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for NBEA - Select products 50% OFF >
- * NBEA CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
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-
OriGene CRISPR knockouts for NBEA
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for NBEA
-
Santa Cruz Biotechnology (SCBT) CRISPR for NBEA
miRNA for NBEA Gene
- miRTarBase miRNAs that target NBEA
-
- mmu-miR-17-5p (MIRT009986)
- mmu-miR-19b-3p (MIRT012402)
- hsa-miR-548b-3p (MIRT016246)
- hsa-miR-335-5p (MIRT016751)
- hsa-miR-9-5p (MIRT021372)
- hsa-miR-128-3p (MIRT021882)
- hsa-miR-21-5p (MIRT030706)
- hsa-miR-935 (MIRT036648)
- hsa-miR-18a-5p (MIRT050693)
- hsa-miR-377-3p (MIRT440139)
- hsa-miR-485-3p (MIRT440140)
- hsa-miR-127-3p (MIRT440141)
- hsa-miR-409-5p (MIRT440143)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for NBEA
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Clone Products
- Applied Biological Materials (abm): Clones for NBEA - Select products 50% OFF >
- * NBEA as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
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- Sino Biological Human cDNA Clone for NBEA
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for NBEA
Cell Line Products
-
Horizon Cell Lines for NBEA
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for NBEA Gene
Localization for NBEA Gene
Subcellular locations from UniProtKB/Swiss-Prot for NBEA Gene
- Cytoplasm. Membrane. Peripheral membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| cytosol | 5 |
| golgi apparatus | 4 |
| nucleus | 3 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
- Cytosol (3)
- Golgi apparatus (3)
- Nucleoli (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005802 | trans-Golgi network | IEA,ISS | -- |
| GO:0005829 | cytosol | IEA,ISS | -- |
| GO:0005886 | plasma membrane | IEA,ISS | -- |
Pathways & Interactions for NBEA Gene
Interacting Proteins for NBEA Gene
GPS-Prot Interaction Network for NBEA
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0008104 | protein localization | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for NBEA Gene
Transcripts for NBEA Gene
mRNA/cDNA for NBEA Gene
- 3 REFSEQ mRNAs :
- 14 NCBI additional mRNA sequence :
- 8 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000310336 10794 nts (view in UCSC)
- ENST00000379922 3794 nts (view in UCSC)
- ENST00000379939 10738 nts (view in UCSC)
- ENST00000400445 11119 nts (view in UCSC)
- ENST00000461581 410 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for NBEA - Select products 50% OFF >
- * NBEA CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for NBEA
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for NBEA
-
Santa Cruz Biotechnology (SCBT) CRISPR for NBEA
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for NBEA
- Browse OriGene Inhibitory RNA Products For NBEA
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NBEA
Clone Products
- Applied Biological Materials (abm): Clones for NBEA - Select products 50% OFF >
- * NBEA as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for NBEA
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for NBEA
Relevant External Links for NBEA Gene
- GeneLoc Exon Structure for
- NBEA
Expression for NBEA Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
-
Testis (Reproductive System)
- Leydig Cells Testis Interstitium
-
Limb (Muscoskeletal System)
- Prechondrocytic Mesenchymal Cells Zeugopod
-
Bone (Muscoskeletal System)
- Prechondrocytic Mesenchymal Cells Zeugopod
-
Cartilage (Muscoskeletal System)
- Prechondrocytic Mesenchymal Cells Zeugopod
-
Blood (Hematopoietic System)
- Hematopoietic Stem Cells Hematopoietic Bone Marrow
- Thyroid (Endocrine System)
- Pancreas (Endocrine System)
mRNA differential expression in normal tissues according to GTEx for NBEA Gene
This gene is overexpressed in Brain - Cerebellar Hemisphere (x4.0).
This gene is overexpressed in Fetal Brain (24.9), Urine (16.9), and Heart (8.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for NBEA Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for NBEA
SOURCE GeneReport for Unigene cluster for NBEA Gene:
Hs.491172mRNA Expression by UniProt/SwissProt for NBEA Gene:
Q8NFP9-NBEA_HUMAN
Tissue specificity:
Predominant in many brain structures. Also expressed at medium levels in spleen, thymus, prostate, testis and ovary. Low level expression is seen in heart, kidney, pancreas, skeletal muscle and intestine.
Evidence on tissue expression from TISSUES for NBEA Gene
- Nervous system(4.9)
- Pancreas(2.5)
- Eye(2.4)
Primer Products
-
OriGene qPCR primer pairs for NBEA
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for NBEA Gene
Orthologs for NBEA Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | NBEA 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | NBEA 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | NBEA 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | NBEA 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | NBEA 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Nbea 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | RGD1562629 30 |
|
||
| Chicken (Gallus gallus) |
Aves | NBEA 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
OneToMany | |
| -- 31 |
|
OneToMany | |||
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | nbea 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | nbeaa 31 |
|
OneToMany | |
| nbeab 31 |
|
OneToMany | |||
| LOC565885 30 |
|
||||
| Fruit Fly (Drosophila melanogaster) |
Insecta | rg 30 31 |
|
OneToMany | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP000017 30 |
|
||
| Worm (Caenorhabditis elegans) |
Secernentea | sel-2 30 31 |
|
OneToMany | |
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | BPH1 31 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.9799 31 |
|
OneToMany |
- Species where no ortholog for NBEA was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for NBEA Gene
- ENSEMBL:
- Gene Tree for NBEA (if available)
- TreeFam:
- Gene Tree for NBEA (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for NBEA: view image
Paralogs for NBEA Gene
(5) SIMAP similar genes for NBEA Gene using alignment to 3 proteins:
- NBEA_HUMAN
- F5GXV7_HUMAN
- Q5T321_HUMAN
Pseudogenes.org Pseudogenes for NBEA Gene
Variants for NBEA Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for NBEA Gene
| SNP ID | Clinical significance and condition | Chr 13 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 636250 | Likely Pathogenic: NBEA-related developmental delay and generalized epilepsy | 35,309,588(+) | G/A | MISSENSE_VARIANT | |
| 666336 | Likely Pathogenic: Scrotal hypoplasia | 35,475,401(+) | G/GC | FRAMESHIFT_VARIANT,INTRON_VARIANT | |
| 691451 | Uncertain Significance: Pyloric stenosis; Esophageal atresia | 34,943,031(+) | C/T | MISSENSE_VARIANT | |
| 710184 | Benign: not provided | 35,649,646(+) | A/G | INTRON_VARIANT | |
| 713517 | Benign: not provided | 35,665,194(+) | G/C | INTRON_VARIANT |
Residual Variation Intolerance Score:
0.747% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.97;
74.73% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for NBEA Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NBEA Gene
Disorders for NBEA Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| cerebellar, ocular, craniofacial, and genital syndrome |
|
|
| autism |
|
|
| combined oxidative phosphorylation deficiency 9 |
|
|
| pervasive developmental disorder |
|
|
Search NBEA in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for NBEA
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for NBEA Gene
Publications for NBEA Gene
- Crystal structure of the BEACH domain reveals an unusual fold and extensive association with a novel PH domain. (PMID: 12234919) Jogl G … Tong L (The EMBO journal 2002) 3 4 23
- The neurobeachin gene (Nbea) identifies a new region of homology between mouse central chromosome 3 and human chromosome 13q13. (PMID: 10501977) Gilbert DJ … Kilimann MW (Mammalian genome : official journal of the International Mammalian Genome Society 1999) 2 3 23
- Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey SD … DREAM investigators (Diabetes care 2010) 3 41
- Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. (PMID: 19086053) Gratacòs M … Psychiatric Genetics Network Group (American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009) 3 41
- Neurobeachin (NBEA) is a target of recurrent interstitial deletions at 13q13 in patients with MGUS and multiple myeloma. (PMID: 19135901) O'Neal J … Tomasson MH (Experimental hematology 2009) 3 23
ExternalLinks
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- antibodies-online: Show 11 available Neurobeachin Antibodies ranked by validation data
- Compare Top Neurobeachin Antibodies
- antibodies-online: Show 5 available Neurobeachin Elisa Kits ranked by validation data
- Compare Top Neurobeachin Elisa Kits
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- antibodies-online: Search results for available Neurobeachin related products ranked by validation data
- Horizon Cell Lines for NBEA
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for NBEA
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for NBEA
- Search GeneCopoeia for miRNA 3'UTR Target clone products for NBEA
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NBEA
- Signalway ELISA kits for NBEA
Sources for NBEA Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB