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Aliases for NBDY Gene

Aliases for NBDY Gene

  • Negative Regulator Of P-Body Association 2 3 3 5
  • Non-Annotated P-Body Dissociating Polypeptide 2 3
  • Long Intergenic Non-Protein Coding RNA 1420 2 3
  • P-Body Dissociating Protein 3 4
  • Protein NoBody 3 4
  • LINC01420 3 4
  • NoBody 3

External Ids for NBDY Gene

Previous HGNC Symbols for NBDY Gene

  • LINC01420

Summaries for NBDY Gene

GeneCards Summary for NBDY Gene

NBDY (Negative Regulator Of P-Body Association) is a Protein Coding gene.

UniProtKB/Swiss-Prot for NBDY Gene

  • Promotes dispersal of P-body components and is likely to play a role in the mRNA decapping process.

Additional gene information for NBDY Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NBDY Gene

Genomics for NBDY Gene

GeneHancer (GH) Regulatory Elements for NBDY Gene

Promoters and enhancers for NBDY Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0XJ056728 Promoter/Enhancer 2.1 EPDnew FANTOM5 Ensembl ENCODE 650.7 +0.7 660 2.6 HDGF PKNOX1 SIN3A YY1 ZNF335 POLR3A EGR1 ZNF366 ZSCAN5C ZNF143 NBDY SPIN2B MTHFD1P1 UBQLN2 ENSG00000226310 GC0XP056733
GH0XJ056562 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 650.1 -164.2 -164247 4.8 HDGF PKNOX1 ATF1 ARNT ARID4B SIN3A DMAP1 ZNF48 YY1 POLR2B UBQLN2 NBDY SPIN2B ENSG00000230105
GH0XJ056618 Promoter 0.6 EPDnew 650.1 -110.9 -110869 0.1 POLR2A ENSG00000230105 NBDY UBQLN2
GH0XJ057335 Enhancer 0.7 ENCODE 4.9 +606.6 606647 1.6 SOX13 FOXA2 RARA CTBP1 FOSL2 FOS MIXL1 GATAD2A SOX5 FOXA3 MTHFD1P1 SPIN2B NBDY GC0XP057239 FAAH2
GH0XJ056503 Enhancer 0.4 ENCODE 5.1 -225.0 -224985 1.5 CTCF STAT1 SPIN2B UBQLN2 NBDY GC0XP056286
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around NBDY on UCSC Golden Path with GeneCards custom track

Genomic Locations for NBDY Gene

Genomic Locations for NBDY Gene
chrX:56,729,241-56,818,380
(GRCh38/hg38)
Size:
89,140 bases
Orientation:
Plus strand
chrX:56,755,692-56,844,813
(GRCh37/hg19)
Size:
89,122 bases
Orientation:
Plus strand

Genomic View for NBDY Gene

Genes around NBDY on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NBDY Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NBDY Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NBDY Gene

Proteins for NBDY Gene

  • Protein details for NBDY Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A0A0U1RRE5-NBDY_HUMAN
    Recommended name:
    Negative regulator of P-body association
    Protein Accession:
    A0A0U1RRE5

    Protein attributes for NBDY Gene

    Size:
    68 amino acids
    Molecular mass:
    7025 Da
    Quaternary structure:
    • Interacts with mRNA decapping proteins DCP1A, DCP2 and EDC4.

neXtProt entry for NBDY Gene

Post-translational modifications for NBDY Gene

No Post-translational modifications

Other Protein References for NBDY Gene

No data available for DME Specific Peptides for NBDY Gene

Domains & Families for NBDY Gene

Gene Families for NBDY Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for NBDY Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with NBDY: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for NBDY Gene

Function for NBDY Gene

Molecular function for NBDY Gene

UniProtKB/Swiss-Prot Function:
Promotes dispersal of P-body components and is likely to play a role in the mRNA decapping process.

Phenotypes From GWAS Catalog for NBDY Gene

Gene Ontology (GO) - Molecular Function for NBDY Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 27918561
genes like me logo Genes that share ontologies with NBDY: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NBDY Gene

Localization for NBDY Gene

Subcellular locations from UniProtKB/Swiss-Prot for NBDY Gene

Cytoplasm, P-body. Note=Localizes to P-bodies at low concentrations without dissociating them. {ECO:0000269 PubMed:27918561}.

Gene Ontology (GO) - Cellular Components for NBDY Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000932 P-body IDA 27918561
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with NBDY: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for NBDY Gene

Pathways & Interactions for NBDY Gene

No Data Available

Interacting Proteins for NBDY Gene

Gene Ontology (GO) - Biological Process for NBDY Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000956 nuclear-transcribed mRNA catabolic process IDA 27918561
GO:0006397 mRNA processing IEA --
GO:0010607 negative regulation of cytoplasmic mRNA processing body assembly IDA 27918561
genes like me logo Genes that share ontologies with NBDY: view

No data available for Pathways by source and SIGNOR curated interactions for NBDY Gene

Drugs & Compounds for NBDY Gene

No Compound Related Data Available

Transcripts for NBDY Gene

mRNA/cDNA for NBDY Gene

(2) REFSEQ mRNAs :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for NBDY Gene

No ASD Table

Relevant External Links for NBDY Gene

GeneLoc Exon Structure for
NBDY
ECgene alternative splicing isoforms for
NBDY

Expression for NBDY Gene

NURSA nuclear receptor signaling pathways regulating expression of NBDY Gene:

NBDY
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NBDY Gene

Orthologs for NBDY Gene

Evolution for NBDY Gene

ENSEMBL:
Gene Tree for NBDY (if available)
TreeFam:
Gene Tree for NBDY (if available)
Aminode:
Evolutionary constrained regions (ECRs) for NBDY: view image

No data available for Orthologs for NBDY Gene

Paralogs for NBDY Gene

No data available for Paralogs for NBDY Gene

Variants for NBDY Gene

Sequence variations from dbSNP and Humsavar for NBDY Gene

SNP ID Clin Chr 0X pos Variation AA Info Type
rs1000056284 -- 56,798,872(+) T/C intron_variant
rs1000081165 -- 56,727,421(+) A/C upstream_transcript_variant
rs1000193511 -- 56,799,277(+) G/A intron_variant
rs1000206498 -- 56,761,688(+) G/A intron_variant
rs1000360368 -- 56,784,183(+) C/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for NBDY Gene

Variant ID Type Subtype PubMed ID
dgv4243n106 CNV duplication 24896259
dgv4593e59 CNV duplication 20981092
esv1000400 CNV insertion 20482838
esv22149 CNV gain+loss 19812545
esv2758867 CNV gain+loss 17122850
esv32659 CNV loss 17666407
esv3302637 CNV tandem duplication 20981092
esv3410049 CNV duplication 20981092
esv3573990 CNV loss 25503493
nsv1075322 CNV deletion 25765185
nsv1145828 CNV duplication 26484159
nsv1148553 CNV duplication 26484159
nsv206 CNV insertion 15895083
nsv508777 CNV insertion 20534489
nsv510833 CNV deletion 20534489
nsv515207 CNV gain 21397061
nsv527262 CNV gain 19592680
nsv6917 CNV deletion 18451855
nsv6918 CNV insertion 18451855
nsv953417 CNV duplication 24416366
nsv9944 CNV gain 18304495
nsv9945 CNV gain 18304495

Additional Variant Information for NBDY Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
NBDY

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for NBDY Gene

Disorders for NBDY Gene

No disorders were found for NBDY Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NBDY Gene

Publications for NBDY Gene

  1. A human microprotein that interacts with the mRNA decapping complex. (PMID: 27918561) D'Lima NG … Slavoff SA (Nature chemical biology 2017) 2 3 4 58
  2. Genome-wide association study identifies loci affecting blood copper, selenium and zinc. (PMID: 23720494) Evans DM … Whitfield JB (Human molecular genetics 2013) 3 58
  3. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross MT … Bentley DR (Nature 2005) 4 58
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for NBDY Gene

Sources for NBDY Gene

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