Aliases for NARS2 Gene
External Ids for NARS2 Gene
Previous HGNC Symbols for NARS2 Gene
Previous GeneCards Identifiers for NARS2 Gene
This gene encodes a putative member of the class II family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of asparagine to tRNA molecules. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency 24 (COXPD24). [provided by RefSeq, Mar 2015]
GeneCards Summary for NARS2 Gene
NARS2 (Asparaginyl-TRNA Synthetase 2, Mitochondrial) is a Protein Coding gene. Diseases associated with NARS2 include Combined Oxidative Phosphorylation Deficiency 24 and Deafness, Autosomal Recessive 94. Among its related pathways are tRNA Aminoacylation and Ectoderm Differentiation. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and aminoacyl-tRNA ligase activity. An important paralog of this gene is NARS1.