Aliases for NARFL Gene
External Ids for NARFL Gene
Previous GeneCards Identifiers for NARFL Gene
GeneCards Summary for NARFL Gene
NARFL (Nuclear Prelamin A Recognition Factor Like) is a Protein Coding gene. Diseases associated with NARFL include Commensal Bacterial Infectious Disease and Blood Group, Globoside System. Among its related pathways are Metabolism and Cytosolic iron-sulfur cluster assembly. Gene Ontology (GO) annotations related to this gene include 4 iron, 4 sulfur cluster binding and NADH dehydrogenase activity. An important paralog of this gene is NARF.
UniProtKB/Swiss-Prot for NARFL Gene
Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect.