Aliases for NAPEPLD Gene
External Ids for NAPEPLD Gene
Previous GeneCards Identifiers for NAPEPLD Gene
NAPEPLD is a phospholipase D type enzyme that catalyzes the release of N-acylethanolamine (NAE) from N-acyl-phosphatidylethanolamine (NAPE) in the second step of the biosynthesis of N-acylethanolamine (Okamoto et al., 2004 [PubMed 14634025]).[supplied by OMIM, Oct 2008]
GeneCards Summary for NAPEPLD Gene
NAPEPLD (N-Acyl Phosphatidylethanolamine Phospholipase D) is a Protein Coding gene. Among its related pathways are HIV Life Cycle and Retinoid cycle disease events. Gene Ontology (GO) annotations related to this gene include phospholipase activity and N-acylphosphatidylethanolamine-specific phospholipase D activity.
UniProtKB/Swiss-Prot for NAPEPLD Gene
Hydrolyzes N-acyl-phosphatidylethanolamines (NAPEs) to produce N-acylethanolamines (NAEs) and phosphatidic acid. Responsible for the generation of anandamide (N-arachidonoylethanolamine), the ligand of cannabinoid and vanilloid receptors (By similarity).