Aliases for NAP1L4 Gene
External Ids for NAP1L4 Gene
Previous GeneCards Identifiers for NAP1L4 Gene
This gene encodes a member of the nucleosome assembly protein (NAP) family which can interact with both core and linker histones. It can shuttle between the cytoplasm and nucleus, suggesting a role as a histone chaperone. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. [provided by RefSeq, Jul 2008]
GeneCards Summary for NAP1L4 Gene
NAP1L4 (Nucleosome Assembly Protein 1 Like 4) is a Protein Coding gene. Diseases associated with NAP1L4 include Beckwith-Wiedemann Syndrome and Wilms Tumor 5. Gene Ontology (GO) annotations related to this gene include unfolded protein binding. An important paralog of this gene is NAP1L1.
UniProtKB/Swiss-Prot Summary for NAP1L4 Gene
Acts as histone chaperone in nucleosome assembly.