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NAB1 (NGFI-A Binding Protein 1) is a Protein Coding gene. Diseases associated with NAB1 include Neuropathy, Congenital Hypomyelinating, 1, Autosomal Recessive and Hypertrophic Neuropathy Of Dejerine-Sottas. Among its related pathways are Integrated Breast Cancer Pathway. Gene Ontology (GO) annotations related to this gene include transcription factor binding. An important paralog of this gene is NAB2.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003712 | transcription coregulator activity | IEA | -- |
GO:0008134 | transcription factor binding | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IEA,NAS | 8668170 |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Integrated Breast Cancer Pathway |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0001958 | endochondral ossification | IEA | -- |
GO:0006355 | regulation of transcription, DNA-templated | IEA,NAS | 8668170 |
GO:0014037 | Schwann cell differentiation | IEA | -- |
GO:0042552 | myelination | IEA | -- |
GO:0045682 | regulation of epidermis development | IEA | -- |
ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d | · | 6e | · | 6f | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13a | · | 13b | · | 13c |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
SP2: | |||||||||||||||||||||||||||||||||||||||||||||||
SP3: | - | ||||||||||||||||||||||||||||||||||||||||||||||
SP4: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
SP5: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
SP6: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
SP7: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
SP8: | |||||||||||||||||||||||||||||||||||||||||||||||
SP9: | - | ||||||||||||||||||||||||||||||||||||||||||||||
SP10: | - | - | - | - | - |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | NAB1 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | NAB1 30 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | NAB1 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Nab1 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Nab1 30 |
|
||
Dog (Canis familiaris) |
Mammalia | NAB1 30 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | NAB1 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | NAB1 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | nab1 30 |
|
||
Str.19373 30 |
|
||||
African clawed frog (Xenopus laevis) |
Amphibia | Xl.15920 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | nab1b 30 31 |
|
OneToMany | |
nab1a 31 |
|
OneToMany | |||
Fruit Fly (Drosophila melanogaster) |
Insecta | nab 31 |
|
OneToMany | |
Worm (Caenorhabditis elegans) |
Secernentea | mab-10 31 |
|
OneToMany | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.6864 31 |
|
OneToMany | |
Sea Vase (Ciona intestinalis) |
Ascidiacea | Cin.11359 30 |
|
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv1200e212 | CNV | loss | 25503493 |
esv3584252 | CNV | loss | 25503493 |
nsv1072472 | CNV | deletion | 25765185 |
nsv3082 | CNV | insertion | 18451855 |
nsv834492 | CNV | gain | 17160897 |
Disorder | Aliases | PubMed IDs |
---|---|---|
neuropathy, congenital hypomyelinating, 1, autosomal recessive |
|
|
hypertrophic neuropathy of dejerine-sottas |
|
|