Free for academic non-profit institutions. Other users need a Commercial license
Aliases for NAA40 Gene
Aliases for NAA40 Gene
- NatD 3 4
- N(Alpha)-Acetyltransferase 40, NatD Catalytic Subunit, Homolog (S. Cerevisiae) 2
- N(Alpha)-Acetyltransferase 40, NatD Catalytic Subunit, Homolog 3
- N(Alpha)-Acetyltransferase 40, NatD Catalytic Subunit 2
- N-Alpha Acetyl Transferase 40 3
- NatD Catalytic Subunit 3
- EC 2.3.1.257 4
- FLJ13848 2
- NAA40 5
External Ids for NAA40 Gene
- HGNC: 25845
- NCBI Entrez Gene: 79829
- Ensembl: ENSG00000110583
- UniProtKB/Swiss-Prot: Q86UY6
Previous HGNC Symbols for NAA40 Gene
- NAT11
Previous GeneCards Identifiers for NAA40 Gene
- GC11P063706
- GC11P060036
Summaries for NAA40 Gene
GeneCards Summary for NAA40 Gene
NAA40 (N-Alpha-Acetyltransferase 40, NatD Catalytic Subunit) is a Protein Coding gene. Diseases associated with NAA40 include Ogden Syndrome and Microphthalmia, Syndromic 1. Among its related pathways are Cytochrome P450 - arranged by substrate type. Gene Ontology (GO) annotations related to this gene include N-acetyltransferase activity.
UniProtKB/Swiss-Prot Summary for NAA40 Gene
-
N-alpha-acetyltransferase that specifically mediates the acetylation of the N-terminal residues of histones H4 and H2A (PubMed:21935442, PubMed:25619998). In contrast to other N-alpha-acetyltransferase, has a very specific selectivity for histones H4 and H2A N-terminus and specifically recognizes the 'Ser-Gly-Arg-Gly sequence' (PubMed:21935442, PubMed:25619998). Acts as a negative regulator of apoptosis (PubMed:26666750). May play a role in hepatic lipid metabolism (By similarity).
Additional gene information for NAA40 Gene
- HGNC (25845)
- NCBI Entrez Gene (79829)
- Ensembl (ENSG00000110583)
- UniProtKB/Swiss-Prot (Q86UY6)
- Open Targets Platform(ENSG00000110583)
- Search for NAA40 at DataMed
- Search for NAA40 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for NAA40 Gene
Genomics for NAA40 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for NAA40 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around NAA40 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for NAA40
Genomic Locations for NAA40 Gene
Latest Assembly
- chr11:63,938,959-63,957,322
- (GRCh38/hg38)
- Size:
- 18,364 bases
- Orientation:
- Plus strand
Previous Assembly
- chr11:63,706,474-63,724,791
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 18,318 bases
- Orientation:
- Plus strand
- chr11:63,706,431-63,724,800
- (GRCh37/hg19 by Ensembl)
- Size:
- 18,370 bases
- Orientation:
- Plus strand
Genomic View for NAA40 Gene
Genes around NAA40 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q13.1 by HGNC
- 11q13.1 by Entrez Gene
- 11q13.1 by Ensembl
NAA40 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for NAA40 Gene
Proteins for NAA40 Gene
-
Protein details for NAA40 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q86UY6-NAA40_HUMAN
- Recommended name:
- N-alpha-acetyltransferase 40
- Protein Accession:
- Q86UY6
- B4DR03
- B4DU10
- Q5HYL5
- Q9H897
Protein attributes for NAA40 Gene
- Size:
- 237 amino acids
- Molecular mass:
- 27194 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=CAI46006.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact.; Evidence={ECO:0000305};
Protein Expression for NAA40 Gene
Post-translational modifications for NAA40 Gene
Other Protein References for NAA40 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- LifeSpan BioSciences NAA40 Antibody
-
Custom Antibody ServicesOriGene Antibodies for NAA40
- Novus Biologicals Antibodies for NAA40
-
Abcam antibodies for NAA40
- Invitrogen Antibodies for NAA40 (AFLGC-NAA40)
- antibodies-online: Show 4 available NAA40 Antibodies ranked by validation data
-
Boster Bio Antibodies for NAA40
-
Custom Antibody ServicesProSci Antibodies for NAA40
Protein products for research
- Search Origene for MassSpec and Protein Over-expression Lysates for NAA40
- Origene Custom Protein Services for NAA40
-
Abcam proteins for NAA40
Assay products for research
No data available for DME Specific Peptides for NAA40 Gene
Domains & Families for NAA40 Gene
Gene Families for NAA40 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted intracellular proteins
Protein Domains for NAA40 Gene
- InterPro:
- Blocks:
-
- GCN5-related N-acetyltransferase
- ProtoNet:
Suggested Antigen Peptide Sequences for NAA40 Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ58929 (B4DR03_HUMAN)
- cDNA FLJ57593 (B4DU10_HUMAN)
- N-alpha acetyl transferase 40 (F2YHM7_HUMAN)
- N-acetyltransferase 11 (NAA40_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q86UY6- Family:
-
- Belongs to the acetyltransferase family. NAA40 subfamily.
Function for NAA40 Gene
Molecular function for NAA40 Gene
- UniProtKB/Swiss-Prot Function:
- N-alpha-acetyltransferase that specifically mediates the acetylation of the N-terminal residues of histones H4 and H2A (PubMed:21935442, PubMed:25619998). In contrast to other N-alpha-acetyltransferase, has a very specific selectivity for histones H4 and H2A N-terminus and specifically recognizes the 'Ser-Gly-Arg-Gly sequence' (PubMed:21935442, PubMed:25619998). Acts as a negative regulator of apoptosis (PubMed:26666750). May play a role in hepatic lipid metabolism (By similarity).
- UniProtKB/Swiss-Prot CatalyticActivity:
- Reaction=acetyl-CoA + N-terminal L-seryl-[histone H4] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-seryl-[histone H4]; Xref=Rhea:RHEA:50596, Rhea:RHEA-COMP:12740, Rhea:RHEA-COMP:12743, ChEBI:CHEBI:15378, ChEBI:CHEBI:57287, ChEBI:CHEBI:57288, ChEBI:CHEBI:64738, ChEBI:CHEBI:83690; EC=2.3.1.257; Evidence={ECO:0000269|PubMed:21935442, ECO:0000269|PubMed:25619998};.
- UniProtKB/Swiss-Prot CatalyticActivity:
- Reaction=acetyl-CoA + N-terminal L-seryl-[histone H2A] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-seryl-[histone H2A]; Xref=Rhea:RHEA:50600, Rhea:RHEA-COMP:12742, Rhea:RHEA-COMP:12744, ChEBI:CHEBI:15378, ChEBI:CHEBI:57287, ChEBI:CHEBI:57288, ChEBI:CHEBI:64738, ChEBI:CHEBI:83690; EC=2.3.1.257; Evidence={ECO:0000269|PubMed:21935442, ECO:0000269|PubMed:25619998};.
- UniProtKB/Swiss-Prot Induction:
- Down-regulated in hepatocellular carcinoma tissues.
Enzyme Numbers (IUBMB) for NAA40 Gene
Phenotypes From GWAS Catalog for NAA40 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 32296183 |
| GO:0008080 | N-acetyltransferase activity | IEA | -- |
| GO:0010485 | H4 histone acetyltransferase activity | IDA | 25619998 |
| GO:0016740 | transferase activity | IEA | -- |
| GO:0016746 | transferase activity, transferring acyl groups | IEA | -- |
Phenotypes for NAA40 Gene
- MGI mutant phenotypes for NAA40:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for NAA40:
Animal Models for research
-
Taconic Biosciences Mouse Models for NAA40
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for NAA40 - Starting at $85 >
- * NAA40 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for NAA40
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for NAA40
-
Santa Cruz Biotechnology (SCBT) CRISPR for NAA40
miRNA for NAA40 Gene
- miRTarBase miRNAs that target NAA40
-
- hsa-let-7b-5p (MIRT005239)
- mmu-let-7b-5p (MIRT012254)
- mmu-miR-24-3p (MIRT013923)
- mmu-miR-149-5p (MIRT014817)
- hsa-miR-26b-5p (MIRT029765)
- hsa-miR-4653-3p (MIRT472633)
- hsa-miR-4424 (MIRT472634)
- hsa-miR-383-3p (MIRT472635)
- hsa-miR-3065-3p (MIRT472636)
- hsa-miR-6514-5p (MIRT472637)
- hsa-miR-3617-3p (MIRT472638)
- hsa-miR-4496 (MIRT472639)
- hsa-miR-4662a-3p (MIRT472640)
- hsa-miR-606 (MIRT472641)
- hsa-miR-551b-5p (MIRT472642)
- hsa-miR-29b-3p (MIRT472643)
- hsa-miR-29c-3p (MIRT472644)
- hsa-miR-29a-3p (MIRT472645)
- hsa-miR-561-5p (MIRT515859)
- hsa-miR-190a-3p (MIRT515860)
- hsa-miR-6830-5p (MIRT515861)
- hsa-miR-3074-3p (MIRT515862)
- hsa-miR-5011-5p (MIRT515863)
- hsa-miR-1277-5p (MIRT515864)
- hsa-miR-7151-3p (MIRT701556)
- hsa-miR-5095 (MIRT701557)
- hsa-miR-6504-5p (MIRT701558)
- hsa-miR-3064-5p (MIRT701559)
- hsa-miR-1972 (MIRT701560)
- hsa-miR-6504-3p (MIRT701561)
- hsa-miR-4717-5p (MIRT701562)
- hsa-miR-4438 (MIRT701563)
- hsa-miR-3133 (MIRT740104)
- hsa-miR-3150b-3p (MIRT740316)
- hsa-miR-4446-3p (MIRT744621)
- hsa-miR-4492 (MIRT745290)
- hsa-miR-4498 (MIRT745371)
- hsa-miR-4721 (MIRT747554)
- hsa-miR-4784 (MIRT748833)
- hsa-miR-5001-5p (MIRT749364)
- hsa-miR-6847-5p (MIRT757479)
- hsa-miR-762 (MIRT759506)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for NAA40
- Browse OriGene Inhibitory RNA Products For NAA40
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NAA40
Clone products for research
- Applied Biological Materials (abm): Clones for NAA40 - Starting at $45 >
- * NAA40 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for NAA40
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for NAA40
Cell Lines for research
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for NAA40 Gene
Localization for NAA40 Gene
Subcellular locations from UniProtKB/Swiss-Prot for NAA40 Gene
- Cytoplasm. Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 4 |
| extracellular | 2 |
| cytosol | 2 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| golgi apparatus | 1 |
| peroxisome | 0 |
| endoplasmic reticulum | 0 |
- Cytosol (3)
- Nucleoplasm (3)
- Centriolar satellite (1)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA,IBA | 21873635 |
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005829 | cytosol | IDA | -- |
| GO:0034451 | centriolar satellite | IDA | -- |
Pathways & Interactions for NAA40 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Cytochrome P450 - arranged by substrate type | ||
Pathways by source for NAA40 Gene
1 BioSystems pathway for NAA40 Gene
Interacting Proteins for NAA40 Gene
Selected Interacting proteins:
Q86UY6-NAA40_HUMAN
ENSP00000367024
for NAA40 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for NAA40
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006474 | N-terminal protein amino acid acetylation | IBA,IDA | 25619998 |
| GO:0006629 | lipid metabolic process | IEA | -- |
| GO:0043967 | histone H4 acetylation | IDA | 25619998 |
| GO:0043968 | histone H2A acetylation | IDA | 25619998 |
| GO:0061187 | regulation of chromatin silencing at rDNA | IBA | -- |
No data available for SIGNOR curated interactions for NAA40 Gene
Transcripts for NAA40 Gene
mRNA/cDNA for NAA40 Gene
- 2 REFSEQ mRNAs :
- 13 NCBI additional mRNA sequence :
- 10 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000338447 4707 nts (view in UCSC)
- ENST00000377793 3649 nts (view in UCSC)
- ENST00000534965 958 nts (view in UCSC)
- ENST00000536939 567 nts (view in UCSC)
- ENST00000539656 577 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for NAA40 - Starting at $85 >
- * NAA40 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for NAA40
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for NAA40
-
Santa Cruz Biotechnology (SCBT) CRISPR for NAA40
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for NAA40
- Browse OriGene Inhibitory RNA Products For NAA40
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NAA40
Clone products for research
- Applied Biological Materials (abm): Clones for NAA40 - Starting at $45 >
- * NAA40 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for NAA40
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for NAA40
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | ||||||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | |||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | |||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||
| SP6: | - | - | |||||||||||||||||||||||||||||||
| SP7: | |||||||||||||||||||||||||||||||||
| SP8: |
Relevant External Links for NAA40 Gene
- GeneLoc Exon Structure for
- NAA40
Expression for NAA40 Gene
This gene is overexpressed in Fetal heart (42.0) and Fetal testis (21.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for NAA40 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for NAA40
SOURCE GeneReport for Unigene cluster for NAA40 Gene:
Hs.523753mRNA Expression by UniProt/SwissProt for NAA40 Gene:
Q86UY6-NAA40_HUMAN
Tissue specificity:
Widely expressed; with the highest expression level in liver and the lowest expression in brain (at protein level).
Evidence on tissue expression from TISSUES for NAA40 Gene
- Thyroid gland(4.2)
- Eye(4)
- Nervous system(3.2)
Primer products for research
-
OriGene qPCR primer pairs for NAA40
-
OriGene qPCR primer pairs and template standards for NAA40
Gene Expression Assays for research
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for NAA40 Gene
Orthologs for NAA40 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | NAA40 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | NAT11 31 |
|
OneToOne | |
| NAA40 30 |
|
||||
| Dog (Canis familiaris) |
Mammalia | NAA40 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Naa40 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Naa40 30 17 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | NAA40 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | NAA40 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | NAA40 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | NAA40 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | naa40 30 |
|
||
| Str.2069 30 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.16373 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | naa40 30 31 31 |
|
OneToMany | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP008428 30 |
|
||
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG7593 30 31 |
|
OneToOne | |
| Worm (Caenorhabditis elegans) |
Secernentea | Y38A10A.7 30 31 |
|
OneToOne | |
| Thale Cress (Arabidopsis thaliana) |
eudicotyledons | AT1G18335 30 |
|
||
| Rice (Oryza sativa) |
Liliopsida | Os05g0387800 30 |
|
||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToOne |
- Species where no ortholog for NAA40 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for NAA40 Gene
- ENSEMBL:
- Gene Tree for NAA40 (if available)
- TreeFam:
- Gene Tree for NAA40 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for NAA40: view image
Paralogs for NAA40 Gene
Pseudogenes.org Pseudogenes for NAA40 Gene
No data available for Paralogs for NAA40 Gene
Variants for NAA40 Gene
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
Residual Variation Intolerance Score:
33.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.02;
37.17% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for NAA40 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- NAA40
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for NAA40 Gene
Disorders for NAA40 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| ogden syndrome |
|
|
| microphthalmia, syndromic 1 |
|
|
| hepatocellular carcinoma |
|
|
Search NAA40 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for NAA40
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for NAA40 Gene
Publications for NAA40 Gene
- The human N-alpha-acetyltransferase 40 (hNaa40p/hNatD) is conserved from yeast and N-terminally acetylates histones H2A and H4. (PMID: 21935442) Hole K … Arnesen T (PloS one 2011) 2 3 4
- A synopsis of eukaryotic Nalpha-terminal acetyltransferases: nomenclature, subunits and substrates. (PMID: 19660095) Polevoda B … Sherman F (BMC proceedings 2009) 2 3 4
- Depletion of histone N-terminal-acetyltransferase Naa40 induces p53-independent apoptosis in colorectal cancer cells via the mitochondrial pathway. (PMID: 26666750) Pavlou D … Kirmizis A (Apoptosis : an international journal on programmed cell death 2016) 3 4
- The molecular basis for histone H4- and H2A-specific amino-terminal acetylation by NatD. (PMID: 25619998) Magin RS … Marmorstein R (Structure (London, England : 1993) 2015) 3 4
- Structure of Patt1 human proapoptotic histone acetyltransferase. (PMID: 24248912) Jędrzejewski RP … Kaźmierkiewicz R (Journal of molecular modeling 2013) 3 4
ExternalLinks
Products for NAA40 Gene
- Custom Antibody ServicesOriGene Antibodies for NAA40
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for NAA40
- Origene Custom Protein Services for NAA40
- Origene shrna, sirna, and RNAi products in human, mouse, rat for NAA40
- Browse OriGene Inhibitory RNA Products For NAA40
- OriGene qPCR primer pairs for NAA40
- OriGene qPCR primer pairs and template standards for NAA40
- OriGene CRISPR knockouts for NAA40
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For NAA40
- Sino Biological Human cDNA Clone for NAA40
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for NAA40
- Novus Biologicals proteins and lysates for NAA40
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for NAA40
- Abcam proteins for NAA40
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Taconic Biosciences Mouse Models for NAA40
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for NAA40 (AFLGC-NAA40)
- VectorBuilder Custom and pre-made DNA vectors for NAA40 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for NAA40 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for NAA40 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for NAA40 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for NAA40
- antibodies-online: Show 4 available NAA40 Antibodies ranked by validation data
- antibodies-online: Search results for available NAA40 related products ranked by validation data
- antibodies-online: Search results for available NAA40 related products ranked by validation data
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for NAA40
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for NAA40
- Search GeneCopoeia for miRNA 3'UTR Target clone products for NAA40
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NAA40
- Boster Bio Antibodies for NAA40
- Browse Boster Bio ELISA Kits
Sources for NAA40 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB