Aliases for NAA15 Gene
External Ids for NAA15 Gene
Previous HGNC Symbols for NAA15 Gene
Previous GeneCards Identifiers for NAA15 Gene
N-alpha-acetylation is among the most common post-translational protein modifications in eukaryotic cells. This process involves the transfer of an acetyl group from acetyl-coenzyme A to the alpha-amino group on a nascent polypeptide and is essential for normal cell function. This gene encodes the auxillary subunit of the N-terminal acetyltransferase A (NatA) complex. [provided by RefSeq, Jan 2017]
GeneCards Summary for NAA15 Gene
NAA15 (N-Alpha-Acetyltransferase 15, NatA Auxiliary Subunit) is a Protein Coding gene. Diseases associated with NAA15 include Mental Retardation, Autosomal Dominant 50 and Ogden Syndrome. Among its related pathways are Mesodermal Commitment Pathway. Gene Ontology (GO) annotations related to this gene include N-acetyltransferase activity. An important paralog of this gene is NAA16.
UniProtKB/Swiss-Prot Summary for NAA15 Gene
Auxillary subunit of the N-terminal acetyltransferase A (NatA) complex which displays alpha (N-terminal) acetyltransferase activity. The NAT activity may be important for vascular, hematopoietic and neuronal growth and development. Required to control retinal neovascularization in adult ocular endothelial cells. In complex with XRCC6 and XRCC5 (Ku80), up-regulates transcription from the osteocalcin promoter.