Aliases for MYRIP Gene
External Ids for MYRIP Gene
Previous GeneCards Identifiers for MYRIP Gene
GeneCards Summary for MYRIP Gene
MYRIP (Myosin VIIA And Rab Interacting Protein) is a Protein Coding gene. Diseases associated with MYRIP include Deafness, Autosomal Dominant 50 and Griscelli Syndrome, Type 1. Among its related pathways are Peptide hormone metabolism and Deregulation of Rab and Rab Effector Genes in Bladder Cancer. Gene Ontology (GO) annotations related to this gene include actin binding and protein kinase A binding. An important paralog of this gene is MLPH.
UniProtKB/Swiss-Prot Summary for MYRIP Gene
Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor proteins MYO5A and MYO7A. May link RAB27A-containing vesicles to actin filaments. Functions as a protein kinase A-anchoring protein (AKAP). May act as a scaffolding protein that links PKA to components of the exocytosis machinery, thus facilitating exocytosis, including insulin release (By similarity).