Aliases for MYOZ1 Gene
External Ids for MYOZ1 Gene
Previous HGNC Symbols for MYOZ1 Gene
Previous GeneCards Identifiers for MYOZ1 Gene
The protein encoded by this gene is primarily expressed in the skeletal muscle, and belongs to the myozenin family. Members of this family function as calcineurin-interacting proteins that help tether calcineurin to the sarcomere of cardiac and skeletal muscle. They play an important role in modulation of calcineurin signaling. [provided by RefSeq, Apr 2012]
GeneCards Summary for MYOZ1 Gene
MYOZ1 (Myozenin 1) is a Protein Coding gene. Diseases associated with MYOZ1 include Myopathy, Spheroid Body and Cardiomyopathy, Dilated, 3B. Gene Ontology (GO) annotations related to this gene include FATZ binding. An important paralog of this gene is MYOZ2.
UniProtKB/Swiss-Prot Summary for MYOZ1 Gene
Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis.