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This gene encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to... See more...
Aliases for MYOD1 Gene
Aliases for MYOD1 Gene
External Ids for MYOD1 Gene
- HGNC: 7611
- Entrez Gene: 4654
- Ensembl: ENSG00000129152
- OMIM: 159970
- UniProtKB: P15172
Previous HGNC Symbols for MYOD1 Gene
- MYF3
Previous GeneCards Identifiers for MYOD1 Gene
- GC11P018862
- GC11P018683
- GC11P017780
- GC11P017705
- GC11P017697
- GC11P017425
Summaries for MYOD1 Gene
-
This gene encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis. [provided by RefSeq, Jul 2008]
GeneCards Summary for MYOD1 Gene
MYOD1 (Myogenic Differentiation 1) is a Protein Coding gene. Diseases associated with MYOD1 include Myopathy, Centronuclear, 1 and Distal Arthrogryposis. Among its related pathways are C-MYB transcription factor network and Development NOTCH1-mediated pathway for NF-KB activity modulation. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and protein heterodimerization activity. An important paralog of this gene is MYF5.
UniProtKB/Swiss-Prot Summary for MYOD1 Gene
-
Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity).
Additional gene information for MYOD1 Gene
- Monarch Initiative
- Search for MYOD1 at DataMed
- Search for MYOD1 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MYOD1 Gene
Genomics for MYOD1 Gene
GeneHancer (GH) Regulatory Elements for MYOD1 Gene
Promoters and enhancers for MYOD1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around MYOD1 on UCSC Golden Path with GeneCards custom track
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for MYOD1
- Top Transcription factor binding sites by QIAGEN in the MYOD1 gene promoter:
-
- p300
- PPAR-gamma1
- PPAR-gamma2
Genomic Locations for MYOD1 Gene
Genomic Locations for MYOD1 Gene
- chr11:17,719,563-17,722,136
- (GRCh38/hg38)
- Size:
- 2,574 bases
- Orientation:
- Plus strand
- chr11:17,741,110-17,743,678
- (GRCh37/hg19)
- Size:
- 2,569 bases
- Orientation:
- Plus strand
Genomic View for MYOD1 Gene
Genes around MYOD1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11p15.1 by HGNC
- 11p15.1 by Entrez Gene
- 11p15.1 by Ensembl
MYOD1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MYOD1 Gene
Proteins for MYOD1 Gene
-
Protein details for MYOD1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P15172-MYOD1_HUMAN
- Recommended name:
- Myoblast determination protein 1
- Protein Accession:
- P15172
- O75321
Protein attributes for MYOD1 Gene
- Size:
- 320 amino acids
- Molecular mass:
- 34501 Da
- Quaternary structure:
-
- Efficient DNA binding requires dimerization with another bHLH protein. Seems to form active heterodimers with ITF-2. Interacts with SUV39H1. Interacts with DDX5. Interacts with CHD2. Interacts with TSC22D3 (By similarity). Interacts with SETD3 (By similarity). Interacts with P-TEFB complex; promotes the transcriptional activity of MYOD1 through its CDK9-mediated phosphorylation (By similarity) (PubMed:12037670). Interacts with CSRP3. Interacts with NUPR1 (By similarity).
Protein Expression for MYOD1 Gene
Post-translational modifications for MYOD1 Gene
- Phosphorylated by CDK9. This phosphorylation promotes its function in muscle differentiation.
- Acetylated by a complex containing EP300 and PCAF. The acetylation is essential to activate target genes. Conversely, its deacetylation by SIRT1 inhibits its function (By similarity).
- Ubiquitinated on the N-terminus; which is required for proteasomal degradation.
- Methylation at Lys-104 by EHMT2/G9a inhibits myogenic activity.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for MYOD1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- G Biosciences Immunotag™ MYOD1 Antibody
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-
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- Invitrogen Antibodies for MYOD1 (AFLGC-MYOD1)
- antibodies-online: Show 52 available MYOD1 Antibodies ranked by validation data
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- 25 IHC Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 6 IP Antibodies (anti-human)
- 4 FACS Antibodies (anti-human)
- 1 IC Antibody (anti-human)
- 1 IHC (fro) Antibody (anti-human)
- 99 WB Antibodies (anti-mouse)
- 42 IHC (f) Antibodies (anti-mouse)
- 14 IHC Antibodies (anti-mouse)
- 14 IHC (p) Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 7 IP Antibodies (anti-mouse)
- 2 FACS Antibodies (anti-mouse)
- 1 IHC (fro) Antibody (anti-mouse)
- 87 WB Antibodies (anti-rat)
- 42 IHC (f) Antibodies (anti-rat)
- 13 IHC Antibodies (anti-rat)
- 13 IHC (p) Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 6 IP Antibodies (anti-rat)
- 2 FACS Antibodies (anti-rat)
- 1 IHC (fro) Antibody (anti-rat)
-
Santa Cruz Biotechnology (SCBT) Antibodies for MYOD1
- Sino Biological Antibodies for MYOD1
Protein Products
-
OriGene Purified Proteins for MYOD1
- Search Origene for MassSpec and Protein Over-expression Lysates for MYOD1
- Origene Custom Protein Services for MYOD1
-
Abcam proteins for MYOD1
No data available for DME Specific Peptides for MYOD1 Gene
Domains & Families for MYOD1 Gene
Gene Families for MYOD1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Predicted intracellular proteins
- Transcription factors
Protein Domains for MYOD1 Gene
- Blocks:
-
- Basic helix-loop-helix dimerization domain bHLH
- Myogenic basic muscle-specific protein
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for MYOD1 Gene
- GenScript: Design optimal peptide antigens:
-
- Myogenic factor 3 (MYOD1_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MYOD1 Gene
Function for MYOD1 Gene
Molecular function for MYOD1 Gene
- UniProtKB/Swiss-Prot Function:
- Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity).
- GENATLAS Biochemistry:
- myogenic differentiation 1,transcription activator of muscle specific genes,promoting cell cycle exit by inducing CDKNIA
Phenotypes From GWAS Catalog for MYOD1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | IDA | 11076940 |
| GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding | IEA,IBA | 21873635 |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | NAS,TAS | 19274049 |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific | IDA,IEA | 11076940 |
| GO:0003677 | DNA binding | IEA | -- |
Phenotypes for MYOD1 Gene
- MGI mutant phenotypes for MYOD1:
- inferred from 9 alleles
- GenomeRNAi human phenotypes for MYOD1:
-
- Decreased HPV16-GFP infection
- Negative genetic interaction between BLM-/- and BLM+/+
- Negative genetic interaction between PTEN-/- and PTEN+/+
- Decreased viability in esophageal squamous lineage
- Decreased viability
- no effect
- Increased vaccinia virus (VACV) infection
- Decreased influenza A H1N1 (A/WSN/33) virus numbers
- Decreased influenza A/WSN/33 replication
Animal Models for MYOD1 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for MYOD1 - Select products 50% OFF >
- * MYOD1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
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-
OriGene CRISPR knockouts for MYOD1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MYOD1
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-
Santa Cruz Biotechnology (SCBT) CRISPR for MYOD1
miRNA for MYOD1 Gene
- miRTarBase miRNAs that target MYOD1
Transcription Factor Targets for MYOD1 Gene
Targeted motifs for MYOD1 Gene
HOMER Transcription Factor Regulatory Elements motif MYOD1
- Consensus sequence: AGCAGCTGCTGC Submotif: canonical Cell Type: Myotube GEO ID: GSE21614
miRNA Products
Inhibitory RNA Products
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- genomics-online: shRNA clones - Search results for available MYOD1 gene related products
Clone Products
- Applied Biological Materials (abm): Clones for MYOD1 - Select products 50% OFF >
- * MYOD1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * MYOD1 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
- Sino Biological Human cDNA Clone for MYOD1
- Addgene plasmids for MYOD1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MYOD1
- genomics-online: cdna clones - Search results for available MYOD1 gene related products
- orf clones - Search results for available MYOD1 gene related products
Cell Line Products
-
Horizon Cell Lines for MYOD1
No data available for Enzyme Numbers (IUBMB) for MYOD1 Gene
Localization for MYOD1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for MYOD1 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| plasma membrane | 3 |
| extracellular | 3 |
| cytoskeleton | 3 |
| cytosol | 3 |
| mitochondrion | 2 |
| endoplasmic reticulum | 2 |
| lysosome | 2 |
| peroxisome | 1 |
| endosome | 1 |
| golgi apparatus | 1 |
- Nucleoplasm (4)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000790 | nuclear chromatin | ISS,IEA | -- |
| GO:0005634 | nucleus | TAS,IBA | 21873635 |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005667 | transcription factor complex | IEA,ISS | -- |
| GO:0005737 | cytoplasm | IEA | -- |
Pathways & Interactions for MYOD1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Myogenesis |
1.00
|
1.00
|
| 2 | TGF-beta Signaling Pathways | ||
| 3 | Developmental Biology | ||
| 4 | Development NOTCH1-mediated pathway for NF-KB activity modulation |
Development Notch Signaling Pathway
.55
|
|
| 5 | Immune response Function of MEF2 in T lymphocytes |
Development Role of HDAC and calcium/calmodulin-dependent kinase (CaMK) in control of skeletal myogenesis
.36
|
|
Pathways by source for MYOD1 Gene
8 BioSystems pathways for MYOD1 Gene
3 Reactome pathways for MYOD1 Gene
2 GeneGo (Thomson Reuters) pathways for MYOD1 Gene
- Development Notch Signaling Pathway
- Development Role of HDAC and calcium/calmodulin-dependent kinase (CaMK) in control of skeletal myogenesis
1 R&D Systems pathway for MYOD1 Gene
Interacting Proteins for MYOD1 Gene
Selected Interacting proteins:
P15172-MYOD1_HUMAN
ENSP00000250003
for MYOD1 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for MYOD1
SIGNOR curated interactions for MYOD1 Gene
- Activates:
- Inactivates:
- Is activated by:
- Is inactivated by:
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000381 | regulation of alternative mRNA splicing, via spliceosome | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0006357 | regulation of transcription by RNA polymerase II | TAS,IEA | 1846704 |
| GO:0006468 | protein phosphorylation | TAS | 3175662 |
| GO:0007275 | multicellular organism development | IEA | -- |
Transcripts for MYOD1 Gene
mRNA/cDNA for MYOD1 Gene
- 1 REFSEQ mRNAs :
- 8 NCBI additional mRNA sequence :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000250003 1803 bps (ENST00000250003.4)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for MYOD1 - Select products 50% OFF >
- * MYOD1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * MYOD1 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
OriGene CRISPR knockouts for MYOD1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MYOD1
- genomics-online: gRNA clones - Search results for available MYOD1 gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for MYOD1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MYOD1
- Browse OriGene Inhibitory RNA Products For MYOD1
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Clone Products
- Applied Biological Materials (abm): Clones for MYOD1 - Select products 50% OFF >
- * MYOD1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * MYOD1 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
- Sino Biological Human cDNA Clone for MYOD1
- Addgene plasmids for MYOD1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MYOD1
- genomics-online: cdna clones - Search results for available MYOD1 gene related products
- orf clones - Search results for available MYOD1 gene related products
Relevant External Links for MYOD1 Gene
- GeneLoc Exon Structure for
- MYOD1
Expression for MYOD1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Skeletal Muscle (Muscoskeletal System)
- Somite (Muscoskeletal System)
-
Limb (Muscoskeletal System)
- Myoblasts Hindlimb Ventral Muscle
- Mononuclear Myocytes Hindlimb Ventral Muscle
- Mononuclear Myocytes Forelimb Dorsal Muscles
- Myoblasts Forelimb Ventral Muscles
- Mononuclear Myocytes Hindlimb Dorsal Muscle
- NULL (Uncategorized)
-
Eye (Sensory Organs)
- Glycinergic Amacrine Cells Inner Nuclear Layer
-
Neurons
- Glycinergic Amacrine Cells Inner Nuclear Layer
-
Inner Cell Mass (Early Embryonic Tissues)
- Inner Cell Mass Cells Inner Cell Mass
- Gut Tube (Gastrointestinal Tract)
- Adipose (Muscoskeletal System)
- Mesenchymal Stem Cells
mRNA differential expression in normal tissues according to GTEx for MYOD1 Gene
This gene is overexpressed in Muscle - Skeletal (x50.3).
This gene is overexpressed in Platelet (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for MYOD1 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MYOD1
SOURCE GeneReport for Unigene cluster for MYOD1 Gene:
Hs.181768Evidence on tissue expression from TISSUES for MYOD1 Gene
- Muscle(4.9)
- Eye(4.1)
- Nervous system(3.8)
- Liver(3.7)
- Intestine(2.1)
- Pancreas(2)
Primer Products
-
OriGene qPCR primer pairs for MYOD1
-
OriGene qPCR primer pairs and template standards for MYOD1
- genomics-online: primer clones - Search results for available MYOD1 gene related products
Gene Expression Assay Products
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for MYOD1 Gene
Orthologs for MYOD1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | MYOD1 31 30 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | MYOD1 31 30 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | MYOD1 31 30 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Myod1 17 31 30 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Myod1 30 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | MYOD1 31 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | MYOD1 31 30 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | MYOD1 31 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | myod1 30 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | myod1 31 30 |
|
OneToOne | |
| fruit fly (Drosophila melanogaster) |
Insecta | nau 31 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | hlh-1 31 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
- Species where no ortholog for MYOD1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Evolution for MYOD1 Gene
- ENSEMBL:
- Gene Tree for MYOD1 (if available)
- TreeFam:
- Gene Tree for MYOD1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for MYOD1: view image
Paralogs for MYOD1 Gene
Variants for MYOD1 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MYOD1 Gene
| SNP ID | Clinical significance and condition | Chr 11 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 631486 | Pathogenic: Arthrogryposis multiplex congenita; Myopathy, centronuclear, 1 | 17,720,334(+) | G/GC | FRAMESHIFT_VARIANT | |
| rs1471293207 | A breast cancer sample | p.Ala309Val | |||
| rs1554986153 | Uncertain Significance: not provided | 17,721,399(+) | C/A | MISSENSE_VARIANT | |
| rs930939009 | A breast cancer sample | p.Glu262Lys |
Residual Variation Intolerance Score:
32.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.32;
26.12% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for MYOD1 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MYOD1 Gene
Disorders for MYOD1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| myopathy, centronuclear, 1 |
|
|
| distal arthrogryposis |
|
|
| arthrogryposis, distal, type 1a |
|
|
| fetal akinesia deformation sequence 1 |
|
|
| pleomorphic rhabdomyosarcoma |
|
|
Search MYOD1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for MYOD1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- Tumor Gene Database
- (TGDB)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for MYOD1 Gene
Publications for MYOD1 Gene
- Genomewide linkage and peakwide association analyses of carotid plaque in Caribbean Hispanics. (PMID: 20966410) Dong C … Sacco RL (Stroke 2010) 3 41 54
- High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. (PMID: 19453261) Yerges LM … MrOS Research Group (Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2009) 3 41 54
- MyoD and E-protein heterodimers switch rhabdomyosarcoma cells from an arrested myoblast phase to a differentiated state. (PMID: 19299559) Yang Z … Tapscott SJ (Genes & development 2009) 3 23 54
- Estrogen receptor (ER) beta or p53 attenuates ERalpha-mediated transcriptional activation on the BRCA2 promoter. (PMID: 18765668) Jin W … Shao ZM (The Journal of biological chemistry 2008) 3 23 54
- Histone methyltransferase Suv39h1 represses MyoD-stimulated myogenic differentiation. (PMID: 16858404) Mal AK (The EMBO journal 2006) 3 4 54
ExternalLinks
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- 42 IHC (f) Antibodies (anti-rat)
- 13 IHC Antibodies (anti-rat)
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- 12 IF (p) Antibodies (anti-rat)
- 6 IP Antibodies (anti-rat)
- 2 FACS Antibodies (anti-rat)
- 1 IHC (fro) Antibody (anti-rat)
- antibodies-online: Show 20 available MYOD1 Elisa Kits ranked by validation data
- Compare Top MYOD1 Elisa Kits
- antibodies-online: Show 13 available MYOD1 Proteins ranked by validation data
- Compare Top MYOD1 Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for MYOD1
- Search Santa Cruz Biotechnology (SCBT) for MYOD1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for MYOD1
- Horizon Cell Lines for MYOD1
- genomics-online: cdna clones - Search results for available MYOD1 gene related products
- orf clones - Search results for available MYOD1 gene related products
- genomics-online: gRNA clones - Search results for available MYOD1 gene related products
- genomics-online: primer clones - Search results for available MYOD1 gene related products
- genomics-online: shRNA clones - Search results for available MYOD1 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MYOD1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MYOD1
- Search GeneCopoeia for miRNA 3'UTR Target clone products for MYOD1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MYOD1
Sources for MYOD1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) H-invDB
- (47) HORDE
- (48) HUGE
- (49) IMGT
- (50) Leiden
- (51) miRBase
- (52) DME
- (53) OriGene
- (54) PubMed
- (55) R&D Systems
- (56) TGDB
- (57) Tocris
- (58) Abcam
- (59) Novus Biologicals
- (60) ProSpec
- (61) Sino Biological
- (62) GenScript
- (63) Qiagen
- (64) OCA
- (65) Proteopedia
- (66) MOPED
- (67) neXtProt
- (68) Reactome
- (69) GeneGo (Thomson Reuters)
- (70) DISEASES
- (71) SIMAP
- (72) GenomeRNAi
- (73) LifeMap
- (74) miRTarBase
- (75) MalaCards
- (76) Invitrogen
- (77) BitterDB
- (78) ESI-BIO
- (79) RefSeq
- (80) BioSystems
- (81) MaxQB
- (82) IUPHAR
- (83) BioGPS
- (84) Illumina
- (85) COMPARTMENTS
- (86) HOMER
- (87) PaxDb
- (88) ApexBio
- (89) Addgene
- (90) antibodies-online
- (91) CYP
- (92) NONCODE
- (93) TreeFam
- (94) PathCards
- (95) GeneReviews
- (96) GeneTex
- (97) Taconic Biosciences
- (98) GTEx
- (99) ProteomicsDB
- (100) SCBT
- (101) DGIdb
- (102) ClinicalTrials
- (103) RVIS
- (104) SIGNOR
- (105) diseasecard
- (106) NIH Rare Diseases
- (107) Orphanet
- (108) UMLS
- (109) GTR
- (110) Disease Ontology
- (111) Genetics Home Reference
- (112) MeSH
- (113) MedlinePlus
- (114) CDC
- (115) NINDS
- (116) NCBI Bookshelf
- (117) ClinVar
- (118) Gene Damage Index
- (119) HPO
- (120) UDN
- (121) VISTA
- (122) FANTOM5
- (123) ENCODE
- (124) ProSci
- (125) Horizon
- (126) The Signaling Pathways Project (SPP)
- (127) IID
- (128) VectorBuilder
- (129) SNPedia
- (130) BRCA Exchange
- (131) CIViC
- (132) ProteoGenix
- (133) dbSUPER
- (134) TISSUES
- (135) Gene ORGANizer
- (136) abm
- (137) Human Protein Atlas
- (138) GWAS Catalog
- (139) Monarch Initiative
- (140) DataMed
- (141) HumanCyc
- (142) genomics-online
- (143) UCNEbase
- (144) EPDnew
- (145) Applied Biosystems
- (146) GlyConnect
- (147) Aminode
- (148) GeneCopoeia
- (149) GPS-Prot
- (150) RNACentral
- (151) LncRNADisease
- (152) LOVD
- (153) miR2Disease
- (154) DiseaseEnhancer
- (155) Boster Bio
- (156) Biorbyt
- (157) Biocompare
- (158) Mastermind
- (159) CTD^2 Dashboard
- (160) CraniofacialAtlas
- (161) GeneImprint
- (162) Synthego
- (163) Bio Basic
- (164) ENA
- (165) GtRNAdb
- (166) LncBase
- (167) LncBook
- (168) LNCipedia
- (169) LncRNAdb
- (170) Modomics
- (171) PDBe
- (172) Rfam
- (173) SILVA
- (174) snOPY
- (175) SRPDB
- (176) GENCODE
- (177) TarBase
- (178) MyBioSource