Aliases for MYO9A Gene
External Ids for MYO9A Gene
Previous GeneCards Identifiers for MYO9A Gene
This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9). Unconventional myosins contain the basic domains of conventional myosins and are further distinguished from class members by their tail domains. They function as actin-based molecular motors. Mutations in this gene have been associated with Bardet-Biedl Syndrome. [provided by RefSeq, Dec 2011]
GeneCards Summary for MYO9A Gene
MYO9A (Myosin IXA) is a Protein Coding gene. Diseases associated with MYO9A include Presynaptic Congenital Myasthenic Syndromes and Congenital Myasthenic Syndrome. Among its related pathways are ERK Signaling and Actin Nucleation by ARP-WASP Complex. Gene Ontology (GO) annotations related to this gene include actin binding and motor activity. An important paralog of this gene is MYO9B.
UniProtKB/Swiss-Prot for MYO9A Gene
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Regulates Rho activity in neurons, has a role in the regulation of neuronal morphology and function (By similarity).