Aliases for MYO9A Gene
External Ids for MYO9A Gene
Previous GeneCards Identifiers for MYO9A Gene
This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9). Unconventional myosins contain the basic domains of conventional myosins and are further distinguished from class members by their tail domains. They function as actin-based molecular motors. Mutations in this gene have been associated with Bardet-Biedl Syndrome. [provided by RefSeq, Dec 2011]
GeneCards Summary for MYO9A Gene
MYO9A (Myosin IXA) is a Protein Coding gene. Diseases associated with MYO9A include Myasthenic Syndrome, Congenital, 24, Presynaptic and Presynaptic Congenital Myasthenic Syndromes. Among its related pathways are p75 NTR receptor-mediated signalling and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include actin binding and motor activity. An important paralog of this gene is MYO9B.
UniProtKB/Swiss-Prot Summary for MYO9A Gene
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Regulates Rho by stimulating it's GTPase activity in neurons. Required for the regulation of neurite branching and motor neuron axon guidance (By similarity).