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Aliases for MYO1D Gene
Aliases for MYO1D Gene
External Ids for MYO1D Gene
- HGNC: 7598
- Entrez Gene: 4642
- Ensembl: ENSG00000176658
- OMIM: 606539
- UniProtKB: O94832
Previous GeneCards Identifiers for MYO1D Gene
- GC17M030586
- GC17M032854
- GC17M030965
- GC17M027844
- GC17M030819
- GC17M027005
Summaries for MYO1D Gene
GeneCards Summary for MYO1D Gene
MYO1D (Myosin ID) is a Protein Coding gene. Diseases associated with MYO1D include Bronchopneumonia and Visceral Heterotaxy. Among its related pathways are Delta508-CFTR traffic / ER-to-Golgi in CF and Actin Nucleation by ARP-WASP Complex. Gene Ontology (GO) annotations related to this gene include actin binding and calmodulin binding. An important paralog of this gene is MYO1G.
UniProtKB/Swiss-Prot Summary for MYO1D Gene
-
Unconventional myosin that functions as actin-based motor protein with ATPase activity (By similarity). Plays a role in endosomal protein trafficking, and especially in the transfer of cargo proteins from early to recycling endosomes (By similarity). Required for normal planar cell polarity in ciliated tracheal cells, for normal rotational polarity of cilia, and for coordinated, unidirectional ciliary movement in the trachea. Required for normal, polarized cilia organization in brain ependymal epithelial cells (By similarity).
Additional gene information for MYO1D Gene
- Monarch Initiative
- Search for MYO1D at DataMed
- Search for MYO1D at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MYO1D Gene
Genomics for MYO1D Gene
GeneHancer (GH) Regulatory Elements for MYO1D Gene
Promoters and enhancers for MYO1D Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around MYO1D on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the MYO1D gene promoter:
-
- E2F
- E2F-1
- E2F-2
- E2F-3a
- E2F-4
- E2F-5
- FAC1
- HOXA5
- Nkx2-5
Genomic Locations for MYO1D Gene
Genomic Locations for MYO1D Gene
- chr17:32,492,522-32,877,177
- (GRCh38/hg38)
- Size:
- 384,656 bases
- Orientation:
- Minus strand
- chr17:30,819,540-31,204,195
- (GRCh37/hg19)
- Size:
- 384,656 bases
- Orientation:
- Minus strand
Genomic View for MYO1D Gene
Genes around MYO1D on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17q11.2 by HGNC
- 17q11.2 by Entrez Gene
- 17q11.2 by Ensembl
MYO1D Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MYO1D Gene
Proteins for MYO1D Gene
-
Protein details for MYO1D Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O94832-MYO1D_HUMAN
- Recommended name:
- Unconventional myosin-Id
- Protein Accession:
- O94832
- A6H8V3
- Q8NHP9
Protein attributes for MYO1D Gene
- Size:
- 1006 amino acids
- Molecular mass:
- 116202 Da
- Quaternary structure:
-
- Interacts (via the two IQ motifs) with calmodulin. Binds an additional calmodulin chain via a third, C-terminal region. Interacts with F-actin.
- SequenceCaution:
-
- Sequence=BAA34447.2; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for MYO1D Gene
Post-translational modifications for MYO1D Gene
Other Protein References for MYO1D Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Creative Biolabs Mouse Anti-MYO1D Recombinant Antibody (CBFYM-2985)
-
Custom Antibody ServicesOriGene Antibodies for MYO1D
- Novus Biologicals Antibodies for MYO1D
-
Abcam antibodies for MYO1D
- Invitrogen Antibodies for MYO1D (AFLGC-MYO1D)
-
Biorbyt antibodies for MYO1D
-
Boster Bio Antibodies for MYO1D
-
Santa Cruz Biotechnology (SCBT) Antibodies for MYO1D
Protein Products
- Creative Biomart Recombinant Human MYO1D cell lysate
-
OriGene Purified Proteins for MYO1D
- Search Origene for MassSpec and Protein Over-expression Lysates for MYO1D
- Origene Custom Protein Services for MYO1D
- antibodies-online: Show 8 available Myosin ID Proteins ranked by validation data
- Compare Top Myosin ID Proteins
-
Quality Products:
-
Abcam proteins for MYO1D
No data available for DME Specific Peptides for MYO1D Gene
Domains & Families for MYO1D Gene
Gene Families for MYO1D Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for MYO1D Gene
- Blocks:
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for MYO1D Gene
- GenScript: Design optimal peptide antigens:
-
- Myosin-Id (MYO1D_HUMAN)
- MYO1D protein (Q8N618_HUMAN)
Graphical View of Domain Structure for InterPro Entry
O94832UniProtKB/Swiss-Prot:
MYO1D_HUMAN :- Binds a calmodulin chain via each of the two IQ domains. IQ domain 1 mediates interaction with calmodulin both in the presence and in the absence of Ca(2+). IQ domain 2 mediates interaction with calmodulin in the presence of Ca(2+).
- Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
- Domain:
-
- Binds a calmodulin chain via each of the two IQ domains. IQ domain 1 mediates interaction with calmodulin both in the presence and in the absence of Ca(2+). IQ domain 2 mediates interaction with calmodulin in the presence of Ca(2+).
- The TH1 domain is required for activity in complementing zebrafish defects in Kupffer's vesicle lumen size.
- Family:
-
- Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
Function for MYO1D Gene
Molecular function for MYO1D Gene
- UniProtKB/Swiss-Prot Function:
- Unconventional myosin that functions as actin-based motor protein with ATPase activity (By similarity). Plays a role in endosomal protein trafficking, and especially in the transfer of cargo proteins from early to recycling endosomes (By similarity). Required for normal planar cell polarity in ciliated tracheal cells, for normal rotational polarity of cilia, and for coordinated, unidirectional ciliary movement in the trachea. Required for normal, polarized cilia organization in brain ependymal epithelial cells (By similarity).
- GENATLAS Biochemistry:
- myosin ID,unconventional,apparently non filamentous,homologous to mouse Myo1f,expressed in cochlea
Phenotypes From GWAS Catalog for MYO1D Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000146 | microfilament motor activity | ISS | -- |
| GO:0000166 | nucleotide binding | IEA | -- |
| GO:0003774 | motor activity | IEA | -- |
| GO:0003779 | actin binding | IEA | -- |
| GO:0005515 | protein binding | IEA | -- |
Phenotypes for MYO1D Gene
- MGI mutant phenotypes for MYO1D:
- inferred from 6 alleles
- GenomeRNAi human phenotypes for MYO1D:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
-
OriGene CRISPR knockouts for MYO1D
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MYO1D
- genomics-online: gRNA clones - Search for available Myosin ID gRNA products
- Overview of 104 available Myosin ID gene related products
- Applied Biological Materials (abm): CRISPR Clones for MYO1D - Select products 50% OFF >
- * MYO1D CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * MYO1D CRISPR applications: KO, Activation, Repression, and more - Browse All
-
Santa Cruz Biotechnology (SCBT) CRISPR for MYO1D
miRNA for MYO1D Gene
- miRTarBase miRNAs that target MYO1D
-
- hsa-mir-155-5p (MIRT020859)
- hsa-mir-615-3p (MIRT040318)
- hsa-mir-193b-3p (MIRT041536)
- hsa-mir-320a (MIRT044717)
- hsa-mir-92a-3p (MIRT049343)
- hsa-mir-31-5p (MIRT049901)
- hsa-mir-218-5p (MIRT440163)
- hsa-mir-2355-3p (MIRT485322)
- hsa-mir-676-3p (MIRT485323)
- hsa-mir-636 (MIRT485324)
- hsa-mir-1914-5p (MIRT485325)
- hsa-mir-499b-3p (MIRT485326)
- hsa-mir-499a-3p (MIRT485327)
- hsa-mir-548t-5p (MIRT485328)
- hsa-mir-548az-5p (MIRT485329)
- hsa-mir-106a-5p (MIRT485330)
- hsa-mir-20a-5p (MIRT485331)
- hsa-mir-20b-5p (MIRT485332)
- hsa-mir-519d-3p (MIRT485333)
- hsa-mir-93-5p (MIRT485334)
- hsa-mir-17-5p (MIRT485335)
- hsa-mir-106b-5p (MIRT485336)
- hsa-mir-526b-3p (MIRT485337)
- hsa-mir-520b (MIRT485338)
- hsa-mir-302a-3p (MIRT485339)
- hsa-mir-302b-3p (MIRT485340)
- hsa-mir-302c-3p (MIRT485341)
- hsa-mir-520c-3p (MIRT485342)
- hsa-mir-302d-3p (MIRT485343)
- hsa-mir-372-3p (MIRT485344)
- hsa-mir-373-3p (MIRT485345)
- hsa-mir-302e (MIRT485346)
- hsa-mir-520e (MIRT485347)
- hsa-mir-520d-3p (MIRT485348)
- hsa-mir-520a-3p (MIRT485349)
- hsa-mir-520f-3p (MIRT485350)
- hsa-mir-32-5p (MIRT727120)
- hsa-mir-92b-3p (MIRT727121)
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for MYO1D
- Browse OriGene Inhibitory RNA Products For MYO1D
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MYO1D
- genomics-online: shRNA clones - Search for available Myosin ID shRNA products
- Overview of 104 available Myosin ID gene related products
Clone Products
- Sino Biological Human cDNA Clone for MYO1D
- Addgene plasmids for MYO1D
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MYO1D
- Applied Biological Materials (abm): Clones for MYO1D - Select products 50% OFF >
- * MYO1D as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * MYO1D tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
Cell Line Products
-
Horizon Cell Lines for MYO1D
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MYO1D Gene
Localization for MYO1D Gene
Subcellular locations from UniProtKB/Swiss-Prot for MYO1D Gene
- Cytoplasm. Perikaryon. Cell projection, dendrite. Early endosome. Cytoplasm, cell cortex. Note=Colocalizes with the actin cytoskeleton in the cell cortex close to the apical cell membrane. Colocalizes with cytoplasmic puncta that are reminiscent of transport vesicles. {ECO:0000250 UniProtKB:Q63357}.
| Compartment | Confidence |
|---|---|
| plasma membrane | 4 |
| cytoskeleton | 4 |
| endoplasmic reticulum | 4 |
| endosome | 4 |
| cytosol | 4 |
| nucleus | 3 |
| peroxisome | 0 |
- Cytosol (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005768 | endosome | ISS | -- |
| GO:0005769 | early endosome | IEA | -- |
| GO:0005790 | smooth endoplasmic reticulum | ISS,IEA | -- |
| GO:0005829 | cytosol | IEA | -- |
Pathways & Interactions for MYO1D Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | PAK Pathway |
Antioxidant Action of Vitamin-C
.56
PAK Pathway
.56
|
Epithelial Adherens Junctions
.36
|
| 2 | Actin Nucleation by ARP-WASP Complex |
Actin Nucleation by ARP-WASP Complex
.66
|
RhoA Pathway
.35
|
| 3 | RhoGDI Pathway |
Fc-GammaR-Mediated Phagocytosis in Macrophages
.33
|
RhoGDI Pathway
.33
|
| 4 | Delta508-CFTR traffic / ER-to-Golgi in CF | ||
| 5 | Pathogenic Escherichia coli infection | ||
Pathways by source for MYO1D Gene
1 KEGG pathway for MYO1D Gene
2 GeneGo (Thomson Reuters) pathways for MYO1D Gene
11 Qiagen pathways for MYO1D Gene
- Actin Nucleation by ARP-WASP Complex
- Antioxidant Action of Vitamin-C
- Cellular Effects of Sildenafil
- Epithelial Adherens Junctions
- Epithelial Tight Junctions
Interacting Proteins for MYO1D Gene
Selected Interacting proteins:
O94832-MYO1D_HUMAN
ENSP00000324527
for MYO1D Gene via
MINT
STRING
IID
GPS-Prot Interaction Network for MYO1D
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0010923 | negative regulation of phosphatase activity | IDA | 19389623 |
| GO:0015031 | protein transport | IEA | -- |
| GO:0030900 | forebrain development | IEA | -- |
| GO:0051641 | cellular localization | ISS,IEA | -- |
| GO:0061502 | early endosome to recycling endosome transport | ISS | -- |
No data available for SIGNOR curated interactions for MYO1D Gene
Drugs & Compounds for MYO1D Gene
No Compound Related Data Available
Drug Products
- Creative Biomart Recombinant Human MYO1D cell lysate
Transcripts for MYO1D Gene
mRNA/cDNA for MYO1D Gene
- (3) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (268) Selected AceView cDNA sequences:
- (16) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000318217 5510 bps (ENST00000318217.9)
- ENST00000394649 5451 bps (ENST00000394649.8)
- ENST00000577576 581 bps (ENST00000577576.1)
- ENST00000577352 1008 bps (ENST00000577352.5)
- ENST00000579584 3500 bps (ENST00000579584.5)
CRISPR Products
-
OriGene CRISPR knockouts for MYO1D
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MYO1D
- genomics-online: gRNA clones - Search for available Myosin ID gRNA products
- Overview of 104 available Myosin ID gene related products
- Applied Biological Materials (abm): CRISPR Clones for MYO1D - Select products 50% OFF >
- * MYO1D CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * MYO1D CRISPR applications: KO, Activation, Repression, and more - Browse All
-
Santa Cruz Biotechnology (SCBT) CRISPR for MYO1D
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for MYO1D
- Browse OriGene Inhibitory RNA Products For MYO1D
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MYO1D
- genomics-online: shRNA clones - Search for available Myosin ID shRNA products
- Overview of 104 available Myosin ID gene related products
Clone Products
- Sino Biological Human cDNA Clone for MYO1D
- Addgene plasmids for MYO1D
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MYO1D
- Applied Biological Materials (abm): Clones for MYO1D - Select products 50% OFF >
- * MYO1D as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * MYO1D tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
Expression for MYO1D Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Bone (Muscoskeletal System)
- Cartilage (Muscoskeletal System)
-
Kidney (Urinary System)
- Presumptive Podocytes Podocyte Layer
- Podocytes Podocyte Layer
-
Epithelial Cells
- Presumptive Podocytes Podocyte Layer
- Podocytes Podocyte Layer
- Inner Cell Mass (Early Embryonic Tissues)
-
Eye (Sensory Organs)
- Glycinergic Amacrine Cells Inner Nuclear Layer
-
Neurons
- Glycinergic Amacrine Cells Inner Nuclear Layer
-
Brain (Nervous System)
- Myelinating Oligodendrocyte Cells Forebrain White Matter
-
Glial Cells
- Myelinating Oligodendrocyte Cells Forebrain White Matter
-
Heart (Cardiovascular System)
- Cardiac Fibroblasts Myocardium
-
Fibroblasts
- Cardiac Fibroblasts Myocardium
- Intestine (Gastrointestinal Tract)
-
Colon (Gastrointestinal Tract)
-
Thyroid (Endocrine System)
-
Gall Bladder (Hepatobiliary System)
-
Esophagus (Gastrointestinal Tract)
mRNA differential expression in normal tissues according to GTEx for MYO1D Gene
This gene is overexpressed in Artery - Aorta (x7.7), Artery - Tibial (x5.5), and Artery - Coronary (x5.0).
This gene is overexpressed in Spinal cord (14.8) and Nasal epithelium (11.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for MYO1D Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of MYO1D Gene:
MYO1DSOURCE GeneReport for Unigene cluster for MYO1D Gene:
Hs.602063mRNA Expression by UniProt/SwissProt for MYO1D Gene:
O94832-MYO1D_HUMAN
Tissue specificity:
Expressed in many tissues. Highest levels in brain, followed by lung and ovary; expression is lowest in spleen.
Evidence on tissue expression from TISSUES for MYO1D Gene
- Nervous system(4.6)
- Intestine(2.9)
- Blood(2.5)
- Pancreas(2.5)
- Skin(2.3)
- Adrenal gland(2)
Primer Products
-
OriGene qPCR primer pairs for MYO1D
- genomics-online: primer clones - Search for available Myosin ID Primer products
- Overview of 104 available Myosin ID gene related products
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for MYO1D Gene
Orthologs for MYO1D Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | MYO1D 33 32 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | MYO1D 33 32 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | MYO1D 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | MYO1D 33 32 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Myo1d 32 |
|
||
| mouse (Mus musculus) |
Mammalia | Myo1d 17 33 32 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | MYO1D 33 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | MYO1D 33 32 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | MYO1D 33 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | myo1d 32 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | MYO1D 33 |
|
OneToOne | |
| si:ch211-94l19.4 32 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | Myo31DF 33 32 |
|
OneToMany | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP010160 32 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | hum-5 33 32 |
|
OneToMany | |
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | MYO3 33 |
|
OneToMany | |
| corn (Zea mays) |
Liliopsida | Zm.442 32 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 33 |
|
OneToMany |
- Species where no ortholog for MYO1D was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Evolution for MYO1D Gene
- ENSEMBL:
- Gene Tree for MYO1D (if available)
- TreeFam:
- Gene Tree for MYO1D (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for MYO1D: view image
Paralogs for MYO1D Gene
Paralogs for MYO1D Gene
- MYO1G 5
- MYO1B 5
- MYO1C 5
- MYO1A 5
- MYO1H 5
- MYO1E 5
- MYO1F 5
- MYO10 5
- MYO7A 5
- MYO15A 5
- MYO5C 5
- MYO7B 5
- MYH7 5
- MYO5A 5
- MYH2 5
- MYH6 5
- MYH4 5
- MYO5B 5
- MYH7B 5
- MYH8 5
- MYH1 5
- MYH11 5
- MYO9A 5
- MYH13 5
- MYH10 5
- MYH9 5
- MYH3 5
- MYH15 5
- MYH14 5
- MYO9B 5
- MYO6 5
- MYO16 5
- MYO3A 5
- MYO3B 5
- MYO19 5
- MYO18B 5
- MYO18A 5
- CCDC158 5
- TMF1 5
- CCDC102A 5
- CGNL1 5
- CCDC102B 5
- CGN 5
- ENSG00000266997 5
(36) SIMAP similar genes for MYO1D Gene using alignment to 6 proteins:
- MYO1D_HUMAN
- J3KRL0_HUMAN
- J3QRN6_HUMAN
- J3QRR2_HUMAN
- K7EIG7_HUMAN
- Q8N618_HUMAN
Variants for MYO1D Gene
| SNP ID | Clin | Chr 17 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000001783 | -- | 32,828,249(-) | G/A | genic_upstream_transcript_variant, intron_variant | |
| rs1000017043 | -- | 32,847,485(-) | G/A | genic_upstream_transcript_variant, intron_variant | |
| rs1000026813 | -- | 32,555,158(-) | T/C | genic_downstream_transcript_variant, intron_variant | |
| rs1000030841 | -- | 32,700,366(-) | C/T | genic_downstream_transcript_variant, intron_variant | |
| rs1000036109 | -- | 32,523,990(-) | T/C | genic_downstream_transcript_variant, intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv568e214 | CNV | gain | 21293372 |
| esv1340589 | CNV | insertion | 17803354 |
| esv2670976 | CNV | deletion | 23128226 |
| esv3306358 | CNV | mobile element insertion | 20981092 |
| esv3342524 | CNV | duplication | 20981092 |
| esv3379868 | CNV | insertion | 20981092 |
| esv3387354 | CNV | insertion | 20981092 |
| esv3388006 | CNV | insertion | 20981092 |
| esv3401653 | CNV | insertion | 20981092 |
| esv3554324 | CNV | deletion | 23714750 |
| esv3582606 | CNV | loss | 25503493 |
| esv3640384 | CNV | loss | 21293372 |
| esv3640385 | CNV | loss | 21293372 |
| esv3640386 | CNV | loss | 21293372 |
| esv3640391 | CNV | loss | 21293372 |
| esv3892994 | CNV | gain | 25118596 |
| nsv1072729 | CNV | deletion | 25765185 |
| nsv1109070 | CNV | deletion | 24896259 |
| nsv1134640 | CNV | deletion | 24896259 |
| nsv472817 | CNV | novel sequence insertion | 20440878 |
| nsv507839 | OTHER | sequence alteration | 20534489 |
| nsv510705 | CNV | deletion | 20534489 |
| nsv519839 | CNV | loss | 19592680 |
| nsv833415 | CNV | gain | 17160897 |
| nsv833416 | CNV | gain | 17160897 |
| nsv833417 | CNV | gain | 17160897 |
Residual Variation Intolerance Score:
10.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.55;
55.82% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for MYO1D Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MYO1D Gene
Disorders for MYO1D Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| bronchopneumonia |
|
|
| visceral heterotaxy |
|
|
Search MYO1D in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for MYO1D
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for MYO1D Gene
Publications for MYO1D Gene
- Genetic association of short sleep duration with hypertension incidence--a 6-year follow-up in the Korean genome and epidemiology study. (PMID: 22322875) Kim SJ … Shin C (Circulation journal : official journal of the Japanese Circulation Society 2012) 3 43 56
- Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey SD … DREAM investigators (Diabetes care 2010) 3 43 56
- Genome-wide association study of pancreatic cancer in Japanese population. (PMID: 20686608) Low SK … Sakamoto H (PloS one 2010) 3 43 56
- High density SNP association study of a major autism linkage region on chromosome 17. (PMID: 17376794) Stone JL … Nelson SF (Human molecular genetics 2007) 3 43 56
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 56
ExternalLinks
Products for MYO1D Gene
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Sources for MYO1D Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
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- (7) GeneLoc
- (8) Gene Wiki
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